| Full name: lymphocyte antigen 86 | Alias Symbol: MD-1|dJ80N2.1 | ||
| Type: protein-coding gene | Cytoband: 6p25.1 | ||
| Entrez ID: 9450 | HGNC ID: HGNC:16837 | Ensembl Gene: ENSG00000112799 | OMIM ID: 605241 |
| Drug and gene relationship at DGIdb | |||
Expression of LY86:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LY86 | 9450 | 205859_at | 0.1647 | 0.8416 | |
| GSE20347 | LY86 | 9450 | 205859_at | -0.0599 | 0.6273 | |
| GSE23400 | LY86 | 9450 | 205859_at | 0.0483 | 0.3643 | |
| GSE26886 | LY86 | 9450 | 205859_at | -0.3362 | 0.1218 | |
| GSE29001 | LY86 | 9450 | 205859_at | -0.0789 | 0.6609 | |
| GSE38129 | LY86 | 9450 | 205859_at | -0.0178 | 0.9289 | |
| GSE45670 | LY86 | 9450 | 205859_at | -0.0120 | 0.9545 | |
| GSE53622 | LY86 | 9450 | 135178 | 0.2344 | 0.0443 | |
| GSE53624 | LY86 | 9450 | 135178 | 0.1036 | 0.3552 | |
| GSE63941 | LY86 | 9450 | 205859_at | 0.2404 | 0.1111 | |
| GSE77861 | LY86 | 9450 | 205859_at | -0.0555 | 0.7805 | |
| GSE97050 | LY86 | 9450 | A_23_P70688 | 0.6032 | 0.1927 | |
| SRP064894 | LY86 | 9450 | RNAseq | 1.6185 | 0.0000 | |
| SRP133303 | LY86 | 9450 | RNAseq | 0.3190 | 0.3044 | |
| SRP159526 | LY86 | 9450 | RNAseq | -1.2086 | 0.1227 | |
| SRP219564 | LY86 | 9450 | RNAseq | 1.4198 | 0.0443 | |
| TCGA | LY86 | 9450 | RNAseq | 0.5344 | 0.0224 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by LY86 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LY86:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LY86 | 9450 | 3 | 6 | 21 | |
| GSE20123 | LY86 | 9450 | 3 | 6 | 21 | |
| GSE43470 | LY86 | 9450 | 8 | 2 | 33 | |
| GSE46452 | LY86 | 9450 | 1 | 10 | 48 | |
| GSE47630 | LY86 | 9450 | 7 | 8 | 25 | |
| GSE54993 | LY86 | 9450 | 1 | 1 | 68 | |
| GSE54994 | LY86 | 9450 | 10 | 3 | 40 | |
| GSE60625 | LY86 | 9450 | 0 | 1 | 10 | |
| GSE74703 | LY86 | 9450 | 7 | 2 | 27 | |
| GSE74704 | LY86 | 9450 | 2 | 2 | 16 | |
| TCGA | LY86 | 9450 | 15 | 29 | 52 |
Total number of gains: 57; Total number of losses: 70; Total Number of normals: 361.
Somatic mutations of LY86:
Generating mutation plots.
Highly correlated genes for LY86:
Showing top 20/271 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LY86 | FAM78A | 0.744718 | 3 | 0 | 3 |
| LY86 | PARVG | 0.734201 | 6 | 0 | 6 |
| LY86 | DPEP2 | 0.701713 | 5 | 0 | 5 |
| LY86 | CD48 | 0.696886 | 11 | 0 | 11 |
| LY86 | GJA4 | 0.694811 | 3 | 0 | 3 |
| LY86 | FERMT3 | 0.685689 | 4 | 0 | 3 |
| LY86 | TBC1D10C | 0.685361 | 6 | 0 | 6 |
| LY86 | CD53 | 0.669406 | 8 | 0 | 7 |
| LY86 | LAPTM5 | 0.661597 | 9 | 0 | 8 |
| LY86 | LST1 | 0.660845 | 9 | 0 | 8 |
| LY86 | NCKAP1L | 0.659771 | 9 | 0 | 7 |
| LY86 | ZC3H12D | 0.657694 | 4 | 0 | 4 |
| LY86 | CD37 | 0.651701 | 9 | 0 | 8 |
| LY86 | SNX20 | 0.649372 | 5 | 0 | 3 |
| LY86 | ZBTB32 | 0.645855 | 4 | 0 | 3 |
| LY86 | CD52 | 0.644482 | 11 | 0 | 9 |
| LY86 | FMNL1 | 0.642378 | 6 | 0 | 4 |
| LY86 | KLHL6 | 0.640172 | 7 | 0 | 6 |
| LY86 | TNFSF8 | 0.633835 | 5 | 0 | 4 |
| LY86 | IL21R | 0.633261 | 9 | 0 | 7 |
For details and further investigation, click here
