| Full name: LIM domain containing 2 | Alias Symbol: MGC10986 | ||
| Type: protein-coding gene | Cytoband: 17q23.3 | ||
| Entrez ID: 80774 | HGNC ID: HGNC:28142 | Ensembl Gene: ENSG00000136490 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LIMD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LIMD2 | 80774 | 218600_at | 0.1529 | 0.6342 | |
| GSE20347 | LIMD2 | 80774 | 218600_at | 0.0523 | 0.4344 | |
| GSE23400 | LIMD2 | 80774 | 218600_at | -0.0461 | 0.3108 | |
| GSE26886 | LIMD2 | 80774 | 218600_at | 0.4439 | 0.0067 | |
| GSE29001 | LIMD2 | 80774 | 218600_at | -0.2162 | 0.0690 | |
| GSE38129 | LIMD2 | 80774 | 218600_at | 0.0003 | 0.9979 | |
| GSE45670 | LIMD2 | 80774 | 218600_at | -0.0135 | 0.9044 | |
| GSE53622 | LIMD2 | 80774 | 66138 | -0.5240 | 0.0000 | |
| GSE53624 | LIMD2 | 80774 | 66138 | -0.2904 | 0.0000 | |
| GSE63941 | LIMD2 | 80774 | 218600_at | 0.1732 | 0.3568 | |
| GSE77861 | LIMD2 | 80774 | 218600_at | -0.1152 | 0.4092 | |
| GSE97050 | LIMD2 | 80774 | A_24_P159635 | 0.0190 | 0.9544 | |
| SRP007169 | LIMD2 | 80774 | RNAseq | 1.6752 | 0.0012 | |
| SRP008496 | LIMD2 | 80774 | RNAseq | 1.1282 | 0.0024 | |
| SRP064894 | LIMD2 | 80774 | RNAseq | 1.4645 | 0.0000 | |
| SRP133303 | LIMD2 | 80774 | RNAseq | -0.0686 | 0.7888 | |
| SRP159526 | LIMD2 | 80774 | RNAseq | 0.5537 | 0.2819 | |
| SRP193095 | LIMD2 | 80774 | RNAseq | 0.7037 | 0.0071 | |
| SRP219564 | LIMD2 | 80774 | RNAseq | 1.3174 | 0.0016 | |
| TCGA | LIMD2 | 80774 | RNAseq | 0.5552 | 0.0000 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by LIMD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LIMD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LIMD2 | 80774 | 3 | 1 | 26 | |
| GSE20123 | LIMD2 | 80774 | 3 | 1 | 26 | |
| GSE43470 | LIMD2 | 80774 | 4 | 0 | 39 | |
| GSE46452 | LIMD2 | 80774 | 31 | 0 | 28 | |
| GSE47630 | LIMD2 | 80774 | 7 | 1 | 32 | |
| GSE54993 | LIMD2 | 80774 | 2 | 5 | 63 | |
| GSE54994 | LIMD2 | 80774 | 9 | 4 | 40 | |
| GSE60625 | LIMD2 | 80774 | 4 | 0 | 7 | |
| GSE74703 | LIMD2 | 80774 | 4 | 0 | 32 | |
| GSE74704 | LIMD2 | 80774 | 3 | 1 | 16 | |
| TCGA | LIMD2 | 80774 | 31 | 9 | 56 |
Total number of gains: 101; Total number of losses: 22; Total Number of normals: 365.
Somatic mutations of LIMD2:
Generating mutation plots.
Highly correlated genes for LIMD2:
Showing top 20/531 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LIMD2 | STAT5A | 0.801582 | 3 | 0 | 3 |
| LIMD2 | TRIM47 | 0.79436 | 3 | 0 | 3 |
| LIMD2 | HERC1 | 0.784481 | 3 | 0 | 3 |
| LIMD2 | GNG7 | 0.760131 | 3 | 0 | 3 |
| LIMD2 | GPR31 | 0.753237 | 3 | 0 | 3 |
| LIMD2 | DAB2IP | 0.752853 | 3 | 0 | 3 |
| LIMD2 | FHL3 | 0.751914 | 3 | 0 | 3 |
| LIMD2 | POLR2A | 0.749914 | 3 | 0 | 3 |
| LIMD2 | LYVE1 | 0.748426 | 3 | 0 | 3 |
| LIMD2 | NINJ1 | 0.738517 | 3 | 0 | 3 |
| LIMD2 | SSNA1 | 0.733232 | 3 | 0 | 3 |
| LIMD2 | VASH1 | 0.731988 | 3 | 0 | 3 |
| LIMD2 | SLC25A27 | 0.726815 | 3 | 0 | 3 |
| LIMD2 | CTDSP1 | 0.726742 | 3 | 0 | 3 |
| LIMD2 | C3orf18 | 0.72674 | 3 | 0 | 3 |
| LIMD2 | MAST2 | 0.724496 | 4 | 0 | 3 |
| LIMD2 | RPL19 | 0.724352 | 3 | 0 | 3 |
| LIMD2 | MIA3 | 0.722674 | 3 | 0 | 3 |
| LIMD2 | LILRB5 | 0.711318 | 4 | 0 | 4 |
| LIMD2 | LIN37 | 0.70916 | 3 | 0 | 3 |
For details and further investigation, click here
