| Full name: ATP binding cassette subfamily D member 4 | Alias Symbol: PMP69|P70R|EST352188 | ||
| Type: protein-coding gene | Cytoband: 14q24.3 | ||
| Entrez ID: 5826 | HGNC ID: HGNC:68 | Ensembl Gene: ENSG00000119688 | OMIM ID: 603214 |
| Drug and gene relationship at DGIdb | |||
Expression of ABCD4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ABCD4 | 5826 | 203981_s_at | 0.2021 | 0.5181 | |
| GSE20347 | ABCD4 | 5826 | 203981_s_at | 0.2350 | 0.0422 | |
| GSE23400 | ABCD4 | 5826 | 203982_s_at | -0.0720 | 0.0914 | |
| GSE26886 | ABCD4 | 5826 | 203981_s_at | 0.6231 | 0.0047 | |
| GSE29001 | ABCD4 | 5826 | 203981_s_at | 0.3201 | 0.2256 | |
| GSE38129 | ABCD4 | 5826 | 203981_s_at | 0.1130 | 0.2257 | |
| GSE45670 | ABCD4 | 5826 | 203981_s_at | 0.1775 | 0.1308 | |
| GSE53622 | ABCD4 | 5826 | 106001 | -0.0258 | 0.8035 | |
| GSE53624 | ABCD4 | 5826 | 106001 | 0.1452 | 0.0166 | |
| GSE63941 | ABCD4 | 5826 | 203981_s_at | -0.2624 | 0.5138 | |
| GSE77861 | ABCD4 | 5826 | 203981_s_at | 0.0543 | 0.8099 | |
| GSE97050 | ABCD4 | 5826 | A_33_P3399598 | 0.0009 | 0.9975 | |
| SRP007169 | ABCD4 | 5826 | RNAseq | -0.0625 | 0.9031 | |
| SRP064894 | ABCD4 | 5826 | RNAseq | 0.6929 | 0.0000 | |
| SRP133303 | ABCD4 | 5826 | RNAseq | -0.0954 | 0.5988 | |
| SRP159526 | ABCD4 | 5826 | RNAseq | 0.0613 | 0.8721 | |
| SRP193095 | ABCD4 | 5826 | RNAseq | -0.0170 | 0.8830 | |
| SRP219564 | ABCD4 | 5826 | RNAseq | 0.1622 | 0.4767 | |
| TCGA | ABCD4 | 5826 | RNAseq | -0.0726 | 0.2018 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ABCD4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ABCD4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ABCD4 | 5826 | 8 | 3 | 19 | |
| GSE20123 | ABCD4 | 5826 | 8 | 3 | 19 | |
| GSE43470 | ABCD4 | 5826 | 8 | 3 | 32 | |
| GSE46452 | ABCD4 | 5826 | 16 | 3 | 40 | |
| GSE47630 | ABCD4 | 5826 | 11 | 8 | 21 | |
| GSE54993 | ABCD4 | 5826 | 3 | 8 | 59 | |
| GSE54994 | ABCD4 | 5826 | 19 | 4 | 30 | |
| GSE60625 | ABCD4 | 5826 | 0 | 2 | 9 | |
| GSE74703 | ABCD4 | 5826 | 7 | 3 | 26 | |
| GSE74704 | ABCD4 | 5826 | 3 | 3 | 14 | |
| TCGA | ABCD4 | 5826 | 32 | 16 | 48 |
Total number of gains: 115; Total number of losses: 56; Total Number of normals: 317.
Somatic mutations of ABCD4:
Generating mutation plots.
Highly correlated genes for ABCD4:
Showing top 20/551 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ABCD4 | MRPL9 | 0.800605 | 3 | 0 | 3 |
| ABCD4 | CHCHD7 | 0.778076 | 3 | 0 | 3 |
| ABCD4 | ACBD6 | 0.772165 | 3 | 0 | 3 |
| ABCD4 | RBM14 | 0.76593 | 3 | 0 | 3 |
| ABCD4 | U2AF2 | 0.76477 | 3 | 0 | 3 |
| ABCD4 | CPNE1 | 0.760625 | 3 | 0 | 3 |
| ABCD4 | PTPN4 | 0.759501 | 3 | 0 | 3 |
| ABCD4 | DNAJC2 | 0.758617 | 3 | 0 | 3 |
| ABCD4 | SLC2A4RG | 0.758352 | 3 | 0 | 3 |
| ABCD4 | RICTOR | 0.756868 | 3 | 0 | 3 |
| ABCD4 | ZNF121 | 0.753493 | 3 | 0 | 3 |
| ABCD4 | EPRS | 0.753129 | 3 | 0 | 3 |
| ABCD4 | CPLX1 | 0.74386 | 3 | 0 | 3 |
| ABCD4 | KLC1 | 0.743029 | 3 | 0 | 3 |
| ABCD4 | WDR37 | 0.742597 | 3 | 0 | 3 |
| ABCD4 | TDG | 0.7387 | 3 | 0 | 3 |
| ABCD4 | SAMD1 | 0.729397 | 3 | 0 | 3 |
| ABCD4 | SNRPE | 0.728717 | 3 | 0 | 3 |
| ABCD4 | ARFRP1 | 0.725033 | 3 | 0 | 3 |
| ABCD4 | PITRM1 | 0.724073 | 3 | 0 | 3 |
For details and further investigation, click here
