| Full name: limb and CNS expressed 1 | Alias Symbol: Lft | ||
| Type: protein-coding gene | Cytoband: 5q15 | ||
| Entrez ID: 167410 | HGNC ID: HGNC:18581 | Ensembl Gene: ENSG00000145721 | OMIM ID: 610466 |
| Drug and gene relationship at DGIdb | |||
Expression of LIX1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LIX1 | 167410 | 236163_at | -0.0139 | 0.9738 | |
| GSE26886 | LIX1 | 167410 | 236163_at | 0.5110 | 0.1263 | |
| GSE45670 | LIX1 | 167410 | 236163_at | -0.1953 | 0.0401 | |
| GSE53622 | LIX1 | 167410 | 138590 | -0.3802 | 0.0679 | |
| GSE53624 | LIX1 | 167410 | 138590 | 0.1283 | 0.3352 | |
| GSE63941 | LIX1 | 167410 | 236163_at | 0.0489 | 0.7927 | |
| GSE77861 | LIX1 | 167410 | 236163_at | -0.0513 | 0.6999 | |
| SRP133303 | LIX1 | 167410 | RNAseq | 0.4357 | 0.0312 | |
| TCGA | LIX1 | 167410 | RNAseq | -2.0209 | 0.0067 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by LIX1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LIX1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LIX1 | 167410 | 1 | 13 | 16 | |
| GSE20123 | LIX1 | 167410 | 1 | 13 | 16 | |
| GSE43470 | LIX1 | 167410 | 3 | 9 | 31 | |
| GSE46452 | LIX1 | 167410 | 0 | 28 | 31 | |
| GSE47630 | LIX1 | 167410 | 0 | 20 | 20 | |
| GSE54993 | LIX1 | 167410 | 8 | 1 | 61 | |
| GSE54994 | LIX1 | 167410 | 1 | 18 | 34 | |
| GSE60625 | LIX1 | 167410 | 0 | 0 | 11 | |
| GSE74703 | LIX1 | 167410 | 2 | 7 | 27 | |
| GSE74704 | LIX1 | 167410 | 1 | 7 | 12 | |
| TCGA | LIX1 | 167410 | 3 | 43 | 50 |
Total number of gains: 20; Total number of losses: 159; Total Number of normals: 309.
Somatic mutations of LIX1:
Generating mutation plots.
Highly correlated genes for LIX1:
Showing all 16 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LIX1 | NPTX2 | 0.694639 | 3 | 0 | 3 |
| LIX1 | CNGA3 | 0.634411 | 3 | 0 | 3 |
| LIX1 | MEIS2 | 0.597615 | 3 | 0 | 3 |
| LIX1 | ANKRD40 | 0.597404 | 3 | 0 | 3 |
| LIX1 | DLEU7 | 0.587499 | 4 | 0 | 3 |
| LIX1 | AMBN | 0.582072 | 3 | 0 | 3 |
| LIX1 | NPY | 0.579954 | 5 | 0 | 3 |
| LIX1 | ACACB | 0.563507 | 5 | 0 | 3 |
| LIX1 | CADPS2 | 0.558598 | 3 | 0 | 3 |
| LIX1 | PRKCQ | 0.544386 | 3 | 0 | 3 |
| LIX1 | SMARCA1 | 0.535167 | 3 | 0 | 3 |
| LIX1 | VAT1L | 0.531391 | 3 | 0 | 3 |
| LIX1 | ACTR1B | 0.52762 | 3 | 0 | 3 |
| LIX1 | SOBP | 0.512401 | 3 | 0 | 3 |
| LIX1 | GFRA4 | 0.510671 | 5 | 0 | 3 |
| LIX1 | DPP10 | 0.510263 | 5 | 0 | 3 |
For details and further investigation, click here
