| Full name: calcium dependent secretion activator 2 | Alias Symbol: CAPS2 | ||
| Type: protein-coding gene | Cytoband: 7q31.32 | ||
| Entrez ID: 93664 | HGNC ID: HGNC:16018 | Ensembl Gene: ENSG00000081803 | OMIM ID: 609978 |
| Drug and gene relationship at DGIdb | |||
Expression of CADPS2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CADPS2 | 93664 | 219572_at | -0.5810 | 0.6837 | |
| GSE20347 | CADPS2 | 93664 | 219572_at | 0.3642 | 0.2269 | |
| GSE23400 | CADPS2 | 93664 | 219572_at | 0.0284 | 0.8633 | |
| GSE26886 | CADPS2 | 93664 | 219572_at | 1.5342 | 0.0038 | |
| GSE29001 | CADPS2 | 93664 | 219572_at | 0.1722 | 0.6808 | |
| GSE38129 | CADPS2 | 93664 | 219572_at | 0.0425 | 0.9306 | |
| GSE45670 | CADPS2 | 93664 | 219572_at | -1.0290 | 0.0099 | |
| GSE53622 | CADPS2 | 93664 | 130557 | -0.3628 | 0.0272 | |
| GSE53624 | CADPS2 | 93664 | 130557 | -0.0169 | 0.9167 | |
| GSE63941 | CADPS2 | 93664 | 219572_at | -2.1152 | 0.0122 | |
| GSE77861 | CADPS2 | 93664 | 219572_at | 0.1240 | 0.4318 | |
| GSE97050 | CADPS2 | 93664 | A_33_P3354001 | -0.1288 | 0.6840 | |
| SRP007169 | CADPS2 | 93664 | RNAseq | 1.8510 | 0.0004 | |
| SRP008496 | CADPS2 | 93664 | RNAseq | 2.0303 | 0.0000 | |
| SRP064894 | CADPS2 | 93664 | RNAseq | 1.1591 | 0.0006 | |
| SRP133303 | CADPS2 | 93664 | RNAseq | 0.1815 | 0.2289 | |
| SRP159526 | CADPS2 | 93664 | RNAseq | 1.2465 | 0.0286 | |
| SRP193095 | CADPS2 | 93664 | RNAseq | 0.0127 | 0.9738 | |
| SRP219564 | CADPS2 | 93664 | RNAseq | -0.0827 | 0.9338 | |
| TCGA | CADPS2 | 93664 | RNAseq | -0.7640 | 0.0000 |
Upregulated datasets: 5; Downregulated datasets: 2.
Survival by CADPS2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CADPS2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CADPS2 | 93664 | 7 | 2 | 21 | |
| GSE20123 | CADPS2 | 93664 | 8 | 2 | 20 | |
| GSE43470 | CADPS2 | 93664 | 2 | 4 | 37 | |
| GSE46452 | CADPS2 | 93664 | 8 | 1 | 50 | |
| GSE47630 | CADPS2 | 93664 | 7 | 4 | 29 | |
| GSE54993 | CADPS2 | 93664 | 3 | 5 | 62 | |
| GSE54994 | CADPS2 | 93664 | 10 | 6 | 37 | |
| GSE60625 | CADPS2 | 93664 | 0 | 0 | 11 | |
| GSE74703 | CADPS2 | 93664 | 2 | 4 | 30 | |
| GSE74704 | CADPS2 | 93664 | 5 | 2 | 13 | |
| TCGA | CADPS2 | 93664 | 28 | 21 | 47 |
Total number of gains: 80; Total number of losses: 51; Total Number of normals: 357.
Somatic mutations of CADPS2:
Generating mutation plots.
Highly correlated genes for CADPS2:
Showing top 20/1016 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CADPS2 | AFF3 | 0.763858 | 3 | 0 | 3 |
| CADPS2 | CELF6 | 0.755901 | 3 | 0 | 3 |
| CADPS2 | C12orf65 | 0.750961 | 3 | 0 | 3 |
| CADPS2 | FUNDC2 | 0.750831 | 3 | 0 | 3 |
| CADPS2 | MYCT1 | 0.734106 | 3 | 0 | 3 |
| CADPS2 | SGCE | 0.701003 | 11 | 0 | 9 |
| CADPS2 | DCHS1 | 0.693597 | 9 | 0 | 8 |
| CADPS2 | SLIT2 | 0.690225 | 9 | 0 | 8 |
| CADPS2 | HS6ST3 | 0.686689 | 3 | 0 | 3 |
| CADPS2 | ITIH5 | 0.682885 | 5 | 0 | 5 |
| CADPS2 | SLC35F1 | 0.682275 | 4 | 0 | 3 |
| CADPS2 | AQP1 | 0.676078 | 6 | 0 | 5 |
| CADPS2 | FOXF1 | 0.675034 | 8 | 0 | 7 |
| CADPS2 | PEG3 | 0.670886 | 6 | 0 | 6 |
| CADPS2 | PRKACA | 0.668167 | 4 | 0 | 3 |
| CADPS2 | MGARP | 0.66719 | 3 | 0 | 3 |
| CADPS2 | IDS | 0.666025 | 6 | 0 | 6 |
| CADPS2 | RSPO3 | 0.665723 | 8 | 0 | 7 |
| CADPS2 | ILDR2 | 0.663202 | 4 | 0 | 3 |
| CADPS2 | FGL2 | 0.663074 | 9 | 0 | 7 |
For details and further investigation, click here
