| Full name: dipeptidyl peptidase like 10 | Alias Symbol: DPRP3|DPL2|DPPY | ||
| Type: protein-coding gene | Cytoband: 2q14.1 | ||
| Entrez ID: 57628 | HGNC ID: HGNC:20823 | Ensembl Gene: ENSG00000175497 | OMIM ID: 608209 |
| Drug and gene relationship at DGIdb | |||
Expression of DPP10:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DPP10 | 57628 | 228598_at | -0.4123 | 0.7268 | |
| GSE26886 | DPP10 | 57628 | 228598_at | -0.0927 | 0.2916 | |
| GSE45670 | DPP10 | 57628 | 228598_at | -0.0882 | 0.5827 | |
| GSE53622 | DPP10 | 57628 | 117406 | -0.5238 | 0.0450 | |
| GSE53624 | DPP10 | 57628 | 117406 | -0.2776 | 0.0995 | |
| GSE63941 | DPP10 | 57628 | 228598_at | 0.0752 | 0.9167 | |
| GSE77861 | DPP10 | 57628 | 228598_at | -0.0868 | 0.1809 | |
| TCGA | DPP10 | 57628 | RNAseq | -3.2433 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by DPP10 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DPP10:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DPP10 | 57628 | 4 | 4 | 22 | |
| GSE20123 | DPP10 | 57628 | 4 | 4 | 22 | |
| GSE43470 | DPP10 | 57628 | 3 | 1 | 39 | |
| GSE46452 | DPP10 | 57628 | 1 | 4 | 54 | |
| GSE47630 | DPP10 | 57628 | 6 | 0 | 34 | |
| GSE54993 | DPP10 | 57628 | 0 | 6 | 64 | |
| GSE54994 | DPP10 | 57628 | 11 | 0 | 42 | |
| GSE60625 | DPP10 | 57628 | 0 | 3 | 8 | |
| GSE74703 | DPP10 | 57628 | 3 | 1 | 32 | |
| GSE74704 | DPP10 | 57628 | 2 | 4 | 14 | |
| TCGA | DPP10 | 57628 | 31 | 8 | 57 |
Total number of gains: 65; Total number of losses: 35; Total Number of normals: 388.
Somatic mutations of DPP10:
Generating mutation plots.
Highly correlated genes for DPP10:
Showing top 20/37 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DPP10 | CDHR3 | 0.756509 | 3 | 0 | 3 |
| DPP10 | SH3GL2 | 0.720146 | 4 | 0 | 4 |
| DPP10 | DPP10-AS1 | 0.67386 | 4 | 0 | 4 |
| DPP10 | GPM6A | 0.654237 | 4 | 0 | 4 |
| DPP10 | SYT4 | 0.641607 | 5 | 0 | 3 |
| DPP10 | BRINP3 | 0.640001 | 4 | 0 | 3 |
| DPP10 | RYR2 | 0.635733 | 3 | 0 | 3 |
| DPP10 | PLB1 | 0.630817 | 3 | 0 | 3 |
| DPP10 | STMN2 | 0.626348 | 5 | 0 | 4 |
| DPP10 | NPY | 0.613091 | 4 | 0 | 3 |
| DPP10 | LDHAL6A | 0.593745 | 3 | 0 | 3 |
| DPP10 | NECAB1 | 0.587915 | 5 | 0 | 3 |
| DPP10 | ENOX1 | 0.587647 | 4 | 0 | 3 |
| DPP10 | CA4 | 0.585622 | 4 | 0 | 3 |
| DPP10 | SMAD9 | 0.584242 | 4 | 0 | 3 |
| DPP10 | CCDC136 | 0.581553 | 4 | 0 | 3 |
| DPP10 | VIP | 0.576354 | 5 | 0 | 3 |
| DPP10 | SLC35F1 | 0.574868 | 5 | 0 | 3 |
| DPP10 | CARTPT | 0.573814 | 5 | 0 | 3 |
| DPP10 | ACTN2 | 0.57029 | 6 | 0 | 3 |
For details and further investigation, click here
