| Full name: sidekick cell adhesion molecule 1 | Alias Symbol: FLJ31425 | ||
| Type: protein-coding gene | Cytoband: 7p22.2 | ||
| Entrez ID: 221935 | HGNC ID: HGNC:19307 | Ensembl Gene: ENSG00000146555 | OMIM ID: 607216 |
| Drug and gene relationship at DGIdb | |||
Expression of SDK1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SDK1 | 221935 | 229912_at | 0.4973 | 0.6051 | |
| GSE26886 | SDK1 | 221935 | 229912_at | 2.6710 | 0.0000 | |
| GSE45670 | SDK1 | 221935 | 229407_at | 0.2341 | 0.4705 | |
| GSE53622 | SDK1 | 221935 | 154141 | 1.5880 | 0.0000 | |
| GSE53624 | SDK1 | 221935 | 68751 | 1.2143 | 0.0000 | |
| GSE63941 | SDK1 | 221935 | 229912_at | -1.5631 | 0.1410 | |
| GSE77861 | SDK1 | 221935 | 229912_at | 0.5545 | 0.0071 | |
| GSE97050 | SDK1 | 221935 | A_23_P93727 | 0.3176 | 0.2027 | |
| SRP007169 | SDK1 | 221935 | RNAseq | 4.7854 | 0.0000 | |
| SRP008496 | SDK1 | 221935 | RNAseq | 5.9036 | 0.0000 | |
| SRP064894 | SDK1 | 221935 | RNAseq | 1.7430 | 0.0000 | |
| SRP133303 | SDK1 | 221935 | RNAseq | 1.5871 | 0.0000 | |
| SRP159526 | SDK1 | 221935 | RNAseq | 2.6385 | 0.0000 | |
| SRP193095 | SDK1 | 221935 | RNAseq | 3.0152 | 0.0000 | |
| SRP219564 | SDK1 | 221935 | RNAseq | 2.3801 | 0.0000 | |
| TCGA | SDK1 | 221935 | RNAseq | 0.4320 | 0.0061 |
Upregulated datasets: 10; Downregulated datasets: 0.
Survival by SDK1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SDK1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SDK1 | 221935 | 16 | 1 | 13 | |
| GSE20123 | SDK1 | 221935 | 16 | 1 | 13 | |
| GSE43470 | SDK1 | 221935 | 6 | 2 | 35 | |
| GSE46452 | SDK1 | 221935 | 13 | 1 | 45 | |
| GSE47630 | SDK1 | 221935 | 10 | 1 | 29 | |
| GSE54993 | SDK1 | 221935 | 0 | 6 | 64 | |
| GSE54994 | SDK1 | 221935 | 21 | 2 | 30 | |
| GSE60625 | SDK1 | 221935 | 0 | 0 | 11 | |
| GSE74703 | SDK1 | 221935 | 6 | 1 | 29 | |
| GSE74704 | SDK1 | 221935 | 9 | 0 | 11 | |
| TCGA | SDK1 | 221935 | 54 | 9 | 33 |
Total number of gains: 151; Total number of losses: 24; Total Number of normals: 313.
Somatic mutations of SDK1:
Generating mutation plots.
Highly correlated genes for SDK1:
Showing top 20/484 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SDK1 | HOXC9 | 0.821978 | 3 | 0 | 3 |
| SDK1 | PAX6 | 0.785225 | 3 | 0 | 3 |
| SDK1 | TMC8 | 0.768899 | 3 | 0 | 3 |
| SDK1 | TFE3 | 0.766022 | 3 | 0 | 3 |
| SDK1 | SHISA8 | 0.749494 | 3 | 0 | 3 |
| SDK1 | LMF1 | 0.748528 | 3 | 0 | 3 |
| SDK1 | PDE4A | 0.741809 | 3 | 0 | 3 |
| SDK1 | RUNX2 | 0.728474 | 4 | 0 | 4 |
| SDK1 | TTYH3 | 0.728323 | 5 | 0 | 5 |
| SDK1 | SYT1 | 0.725738 | 3 | 0 | 3 |
| SDK1 | ASMTL | 0.720429 | 3 | 0 | 3 |
| SDK1 | ADAP1 | 0.71984 | 3 | 0 | 3 |
| SDK1 | ST8SIA1 | 0.716006 | 4 | 0 | 3 |
| SDK1 | ZFPM1 | 0.715769 | 4 | 0 | 4 |
| SDK1 | POLD1 | 0.711946 | 4 | 0 | 3 |
| SDK1 | HSD17B14 | 0.711887 | 3 | 0 | 3 |
| SDK1 | PRR18 | 0.711762 | 3 | 0 | 3 |
| SDK1 | NAT14 | 0.704471 | 7 | 0 | 6 |
| SDK1 | RELB | 0.704338 | 5 | 0 | 5 |
| SDK1 | ZNF446 | 0.702639 | 3 | 0 | 3 |
For details and further investigation, click here
