| Full name: leiomodin 2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7q31.32 | ||
| Entrez ID: 442721 | HGNC ID: HGNC:6648 | Ensembl Gene: ENSG00000170807 | OMIM ID: 608006 |
| Drug and gene relationship at DGIdb | |||
Expression of LMOD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LMOD2 | 442721 | 239057_at | -0.1646 | 0.5069 | |
| GSE26886 | LMOD2 | 442721 | 239057_at | 0.1477 | 0.1325 | |
| GSE45670 | LMOD2 | 442721 | 239057_at | 0.0967 | 0.3624 | |
| GSE53622 | LMOD2 | 442721 | 95487 | 0.0632 | 0.7208 | |
| GSE53624 | LMOD2 | 442721 | 95487 | 0.1264 | 0.2551 | |
| GSE63941 | LMOD2 | 442721 | 239057_at | 0.2257 | 0.1850 | |
| GSE77861 | LMOD2 | 442721 | 239057_at | -0.0856 | 0.5005 | |
| GSE97050 | LMOD2 | 442721 | A_24_P249253 | -1.1588 | 0.2502 | |
| TCGA | LMOD2 | 442721 | RNAseq | -2.6613 | 0.0035 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by LMOD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LMOD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LMOD2 | 442721 | 6 | 2 | 22 | |
| GSE20123 | LMOD2 | 442721 | 7 | 2 | 21 | |
| GSE43470 | LMOD2 | 442721 | 2 | 4 | 37 | |
| GSE46452 | LMOD2 | 442721 | 8 | 1 | 50 | |
| GSE47630 | LMOD2 | 442721 | 7 | 4 | 29 | |
| GSE54993 | LMOD2 | 442721 | 3 | 5 | 62 | |
| GSE54994 | LMOD2 | 442721 | 9 | 7 | 37 | |
| GSE60625 | LMOD2 | 442721 | 0 | 0 | 11 | |
| GSE74703 | LMOD2 | 442721 | 2 | 4 | 30 | |
| GSE74704 | LMOD2 | 442721 | 5 | 2 | 13 | |
| TCGA | LMOD2 | 442721 | 27 | 21 | 48 |
Total number of gains: 76; Total number of losses: 52; Total Number of normals: 360.
Somatic mutations of LMOD2:
Generating mutation plots.
Highly correlated genes for LMOD2:
Showing top 20/23 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LMOD2 | FAM71E1 | 0.604968 | 4 | 0 | 3 |
| LMOD2 | NPAS3 | 0.600756 | 4 | 0 | 4 |
| LMOD2 | DUSP15 | 0.590433 | 3 | 0 | 3 |
| LMOD2 | STAB2 | 0.582365 | 4 | 0 | 3 |
| LMOD2 | RARG | 0.579239 | 3 | 0 | 3 |
| LMOD2 | SMYD1 | 0.579214 | 4 | 0 | 3 |
| LMOD2 | NXF5 | 0.576583 | 3 | 0 | 3 |
| LMOD2 | TTN-AS1 | 0.574333 | 4 | 0 | 3 |
| LMOD2 | AMHR2 | 0.57133 | 3 | 0 | 3 |
| LMOD2 | PSPN | 0.562366 | 3 | 0 | 3 |
| LMOD2 | ATP2B2 | 0.558443 | 4 | 0 | 3 |
| LMOD2 | CPNE7 | 0.555941 | 3 | 0 | 3 |
| LMOD2 | CDHR2 | 0.554578 | 4 | 0 | 3 |
| LMOD2 | RNF151 | 0.528973 | 4 | 0 | 3 |
| LMOD2 | BAAT | 0.525828 | 4 | 0 | 3 |
| LMOD2 | ODF3B | 0.525337 | 4 | 0 | 3 |
| LMOD2 | GRAP | 0.519616 | 4 | 0 | 3 |
| LMOD2 | NOXA1 | 0.518184 | 5 | 0 | 3 |
| LMOD2 | TRPM3 | 0.516523 | 4 | 0 | 3 |
| LMOD2 | OTOF | 0.514984 | 4 | 0 | 3 |
For details and further investigation, click here
