| Full name: SET and MYND domain containing 1 | Alias Symbol: BOP|ZMYND22|KMT3D | ||
| Type: protein-coding gene | Cytoband: 2p11.2 | ||
| Entrez ID: 150572 | HGNC ID: HGNC:20986 | Ensembl Gene: ENSG00000115593 | OMIM ID: 606846 |
| Drug and gene relationship at DGIdb | |||
Expression of SMYD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SMYD1 | 150572 | 243045_at | -0.1305 | 0.6583 | |
| GSE26886 | SMYD1 | 150572 | 243045_at | -0.0643 | 0.6303 | |
| GSE45670 | SMYD1 | 150572 | 243045_at | 0.0205 | 0.8768 | |
| GSE53622 | SMYD1 | 150572 | 21412 | -0.3167 | 0.3985 | |
| GSE53624 | SMYD1 | 150572 | 21412 | 0.6470 | 0.0045 | |
| GSE63941 | SMYD1 | 150572 | 243045_at | 0.3133 | 0.0535 | |
| GSE77861 | SMYD1 | 150572 | 243045_at | -0.1955 | 0.1843 | |
| GSE97050 | SMYD1 | 150572 | A_33_P3379816 | -1.4366 | 0.1215 | |
| TCGA | SMYD1 | 150572 | RNAseq | -1.9272 | 0.1000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SMYD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SMYD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SMYD1 | 150572 | 9 | 2 | 19 | |
| GSE20123 | SMYD1 | 150572 | 9 | 2 | 19 | |
| GSE43470 | SMYD1 | 150572 | 3 | 2 | 38 | |
| GSE46452 | SMYD1 | 150572 | 2 | 3 | 54 | |
| GSE47630 | SMYD1 | 150572 | 7 | 0 | 33 | |
| GSE54993 | SMYD1 | 150572 | 0 | 6 | 64 | |
| GSE54994 | SMYD1 | 150572 | 10 | 0 | 43 | |
| GSE60625 | SMYD1 | 150572 | 0 | 3 | 8 | |
| GSE74703 | SMYD1 | 150572 | 3 | 1 | 32 | |
| GSE74704 | SMYD1 | 150572 | 7 | 0 | 13 | |
| TCGA | SMYD1 | 150572 | 34 | 4 | 58 |
Total number of gains: 84; Total number of losses: 23; Total Number of normals: 381.
Somatic mutations of SMYD1:
Generating mutation plots.
Highly correlated genes for SMYD1:
Showing top 20/249 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SMYD1 | CADM3 | 0.771783 | 4 | 0 | 3 |
| SMYD1 | STK32A | 0.770867 | 3 | 0 | 3 |
| SMYD1 | SNX1 | 0.761186 | 3 | 0 | 3 |
| SMYD1 | POPDC2 | 0.726262 | 4 | 0 | 4 |
| SMYD1 | CAMK2B | 0.715279 | 3 | 0 | 3 |
| SMYD1 | SARDH | 0.702638 | 3 | 0 | 3 |
| SMYD1 | B3GAT2 | 0.693833 | 3 | 0 | 3 |
| SMYD1 | ARHGAP4 | 0.692834 | 3 | 0 | 3 |
| SMYD1 | EPHA7 | 0.691729 | 3 | 0 | 3 |
| SMYD1 | PRKACB | 0.689669 | 3 | 0 | 3 |
| SMYD1 | RXRG | 0.687653 | 4 | 0 | 4 |
| SMYD1 | HAND2 | 0.687293 | 4 | 0 | 3 |
| SMYD1 | ROBO4 | 0.686979 | 3 | 0 | 3 |
| SMYD1 | ADCYAP1R1 | 0.686279 | 3 | 0 | 3 |
| SMYD1 | PRM1 | 0.681446 | 4 | 0 | 4 |
| SMYD1 | PDK2 | 0.680107 | 3 | 0 | 3 |
| SMYD1 | ZNF579 | 0.679139 | 3 | 0 | 3 |
| SMYD1 | NKX2-1 | 0.677558 | 3 | 0 | 3 |
| SMYD1 | GRPR | 0.674896 | 6 | 0 | 5 |
| SMYD1 | GNG7 | 0.672294 | 3 | 0 | 3 |
For details and further investigation, click here
