| Full name: TBC1 domain family member 8 | Alias Symbol: HBLP1|VRP|AD3|GRAMD8 | ||
| Type: protein-coding gene | Cytoband: 2q11.2 | ||
| Entrez ID: 11138 | HGNC ID: HGNC:17791 | Ensembl Gene: ENSG00000204634 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TBC1D8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TBC1D8 | 11138 | 204526_s_at | 0.0832 | 0.8800 | |
| GSE20347 | TBC1D8 | 11138 | 204526_s_at | -0.0851 | 0.6917 | |
| GSE23400 | TBC1D8 | 11138 | 204526_s_at | 0.1254 | 0.2391 | |
| GSE26886 | TBC1D8 | 11138 | 204526_s_at | 0.5277 | 0.0478 | |
| GSE29001 | TBC1D8 | 11138 | 204526_s_at | -0.0119 | 0.9781 | |
| GSE38129 | TBC1D8 | 11138 | 204526_s_at | 0.0772 | 0.6820 | |
| GSE45670 | TBC1D8 | 11138 | 204526_s_at | 0.0385 | 0.8872 | |
| GSE53622 | TBC1D8 | 11138 | 111963 | -0.0073 | 0.9525 | |
| GSE53624 | TBC1D8 | 11138 | 111963 | 0.0079 | 0.9344 | |
| GSE63941 | TBC1D8 | 11138 | 204526_s_at | 1.1766 | 0.1066 | |
| GSE77861 | TBC1D8 | 11138 | 204526_s_at | 0.3596 | 0.1666 | |
| GSE97050 | TBC1D8 | 11138 | A_33_P3309075 | 0.2009 | 0.6181 | |
| SRP007169 | TBC1D8 | 11138 | RNAseq | 0.8555 | 0.0416 | |
| SRP008496 | TBC1D8 | 11138 | RNAseq | 0.7500 | 0.0264 | |
| SRP064894 | TBC1D8 | 11138 | RNAseq | -0.1829 | 0.4560 | |
| SRP133303 | TBC1D8 | 11138 | RNAseq | -0.0851 | 0.6878 | |
| SRP159526 | TBC1D8 | 11138 | RNAseq | 0.1020 | 0.7550 | |
| SRP193095 | TBC1D8 | 11138 | RNAseq | -0.0178 | 0.8873 | |
| SRP219564 | TBC1D8 | 11138 | RNAseq | 0.3776 | 0.5295 | |
| TCGA | TBC1D8 | 11138 | RNAseq | -0.2092 | 0.0018 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TBC1D8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TBC1D8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TBC1D8 | 11138 | 5 | 2 | 23 | |
| GSE20123 | TBC1D8 | 11138 | 5 | 2 | 23 | |
| GSE43470 | TBC1D8 | 11138 | 5 | 1 | 37 | |
| GSE46452 | TBC1D8 | 11138 | 1 | 4 | 54 | |
| GSE47630 | TBC1D8 | 11138 | 7 | 0 | 33 | |
| GSE54993 | TBC1D8 | 11138 | 0 | 6 | 64 | |
| GSE54994 | TBC1D8 | 11138 | 9 | 1 | 43 | |
| GSE60625 | TBC1D8 | 11138 | 0 | 3 | 8 | |
| GSE74703 | TBC1D8 | 11138 | 5 | 1 | 30 | |
| GSE74704 | TBC1D8 | 11138 | 3 | 1 | 16 | |
| TCGA | TBC1D8 | 11138 | 35 | 5 | 56 |
Total number of gains: 75; Total number of losses: 26; Total Number of normals: 387.
Somatic mutations of TBC1D8:
Generating mutation plots.
Highly correlated genes for TBC1D8:
Showing top 20/315 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TBC1D8 | THADA | 0.78703 | 3 | 0 | 3 |
| TBC1D8 | PPHLN1 | 0.765318 | 3 | 0 | 3 |
| TBC1D8 | NRARP | 0.762159 | 3 | 0 | 3 |
| TBC1D8 | ADO | 0.757844 | 3 | 0 | 3 |
| TBC1D8 | MRPS18B | 0.754339 | 3 | 0 | 3 |
| TBC1D8 | ZNF766 | 0.736485 | 3 | 0 | 3 |
| TBC1D8 | NDUFS2 | 0.736049 | 3 | 0 | 3 |
| TBC1D8 | LRP5L | 0.735545 | 3 | 0 | 3 |
| TBC1D8 | SFSWAP | 0.733295 | 4 | 0 | 4 |
| TBC1D8 | CNOT2 | 0.729024 | 4 | 0 | 3 |
| TBC1D8 | NAPEPLD | 0.723632 | 3 | 0 | 3 |
| TBC1D8 | NAPB | 0.722397 | 3 | 0 | 3 |
| TBC1D8 | TRIM26 | 0.721354 | 3 | 0 | 3 |
| TBC1D8 | METTL23 | 0.718597 | 3 | 0 | 3 |
| TBC1D8 | GET4 | 0.717855 | 3 | 0 | 3 |
| TBC1D8 | ORAI3 | 0.713732 | 3 | 0 | 3 |
| TBC1D8 | BIRC6 | 0.712059 | 3 | 0 | 3 |
| TBC1D8 | NMT1 | 0.710064 | 3 | 0 | 3 |
| TBC1D8 | IAH1 | 0.709854 | 3 | 0 | 3 |
| TBC1D8 | FRA10AC1 | 0.707816 | 3 | 0 | 3 |
For details and further investigation, click here
