| Full name: leukocyte associated immunoglobulin like receptor 1 | Alias Symbol: CD305 | ||
| Type: protein-coding gene | Cytoband: 19q13.42 | ||
| Entrez ID: 3903 | HGNC ID: HGNC:6477 | Ensembl Gene: ENSG00000167613 | OMIM ID: 602992 |
| Drug and gene relationship at DGIdb | |||
Expression of LAIR1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LAIR1 | 3903 | 210644_s_at | 0.5996 | 0.3997 | |
| GSE20347 | LAIR1 | 3903 | 208071_s_at | -0.1509 | 0.0925 | |
| GSE23400 | LAIR1 | 3903 | 210644_s_at | 0.0777 | 0.2480 | |
| GSE26886 | LAIR1 | 3903 | 208071_s_at | -0.1073 | 0.3714 | |
| GSE29001 | LAIR1 | 3903 | 210644_s_at | 0.2131 | 0.4037 | |
| GSE38129 | LAIR1 | 3903 | 210644_s_at | 0.1410 | 0.3800 | |
| GSE45670 | LAIR1 | 3903 | 208071_s_at | -0.0496 | 0.6350 | |
| GSE53622 | LAIR1 | 3903 | 24967 | 0.4479 | 0.0008 | |
| GSE53624 | LAIR1 | 3903 | 24967 | 0.4969 | 0.0009 | |
| GSE63941 | LAIR1 | 3903 | 208071_s_at | 0.1681 | 0.1941 | |
| GSE77861 | LAIR1 | 3903 | 208071_s_at | -0.1869 | 0.1177 | |
| GSE97050 | LAIR1 | 3903 | A_33_P3253394 | 0.7611 | 0.1506 | |
| SRP007169 | LAIR1 | 3903 | RNAseq | 2.8344 | 0.0003 | |
| SRP008496 | LAIR1 | 3903 | RNAseq | 2.4756 | 0.0000 | |
| SRP064894 | LAIR1 | 3903 | RNAseq | 1.7029 | 0.0000 | |
| SRP133303 | LAIR1 | 3903 | RNAseq | 0.6637 | 0.0327 | |
| SRP159526 | LAIR1 | 3903 | RNAseq | 0.4281 | 0.4969 | |
| SRP193095 | LAIR1 | 3903 | RNAseq | 0.6623 | 0.0008 | |
| SRP219564 | LAIR1 | 3903 | RNAseq | 1.4759 | 0.0111 | |
| TCGA | LAIR1 | 3903 | RNAseq | 0.3560 | 0.0112 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by LAIR1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LAIR1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LAIR1 | 3903 | 3 | 4 | 23 | |
| GSE20123 | LAIR1 | 3903 | 3 | 3 | 24 | |
| GSE43470 | LAIR1 | 3903 | 2 | 11 | 30 | |
| GSE46452 | LAIR1 | 3903 | 45 | 1 | 13 | |
| GSE47630 | LAIR1 | 3903 | 8 | 6 | 26 | |
| GSE54993 | LAIR1 | 3903 | 17 | 4 | 49 | |
| GSE54994 | LAIR1 | 3903 | 4 | 13 | 36 | |
| GSE60625 | LAIR1 | 3903 | 9 | 0 | 2 | |
| GSE74703 | LAIR1 | 3903 | 2 | 7 | 27 | |
| GSE74704 | LAIR1 | 3903 | 3 | 1 | 16 | |
| TCGA | LAIR1 | 3903 | 19 | 15 | 62 |
Total number of gains: 115; Total number of losses: 65; Total Number of normals: 308.
Somatic mutations of LAIR1:
Generating mutation plots.
Highly correlated genes for LAIR1:
Showing top 20/371 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LAIR1 | PIK3AP1 | 0.789898 | 4 | 0 | 4 |
| LAIR1 | NAIP | 0.784063 | 3 | 0 | 3 |
| LAIR1 | CYTH4 | 0.775287 | 8 | 0 | 8 |
| LAIR1 | IL12RB1 | 0.771616 | 6 | 0 | 6 |
| LAIR1 | IL4I1 | 0.765375 | 4 | 0 | 4 |
| LAIR1 | EPSTI1 | 0.738236 | 4 | 0 | 4 |
| LAIR1 | LCP2 | 0.733312 | 8 | 0 | 7 |
| LAIR1 | PARVG | 0.729575 | 6 | 0 | 5 |
| LAIR1 | EXOC3L2 | 0.728282 | 3 | 0 | 3 |
| LAIR1 | C1QC | 0.723369 | 5 | 0 | 5 |
| LAIR1 | ARHGAP9 | 0.722987 | 5 | 0 | 4 |
| LAIR1 | FANCA | 0.722418 | 4 | 0 | 4 |
| LAIR1 | LILRB1 | 0.72175 | 10 | 0 | 9 |
| LAIR1 | FMNL1 | 0.719542 | 4 | 0 | 3 |
| LAIR1 | GPR65 | 0.716995 | 7 | 0 | 7 |
| LAIR1 | HLA-DMB | 0.716452 | 6 | 0 | 6 |
| LAIR1 | LRRC25 | 0.71614 | 4 | 0 | 3 |
| LAIR1 | SPI1 | 0.715051 | 7 | 0 | 6 |
| LAIR1 | CYBB | 0.713827 | 8 | 0 | 7 |
| LAIR1 | C19orf38 | 0.712277 | 3 | 0 | 3 |
For details and further investigation, click here
