C1QA

 

Full name: complement C1q A chain Alias Symbol: 
Type: protein-coding gene Cytoband: 1p36.12
Entrez ID: 712 HGNC ID: HGNC:1241 Ensembl Gene: ENSG00000173372 OMIM ID: 120550
Drug and gene relationship at DGIdb

 

C1QA involved pathways:

KEGG pathway Description View
hsa04610Complement and coagulation cascades
hsa05133Pertussis
hsa05142Chagas disease (American trypanosomiasis)
hsa05150Staphylococcus aureus infection

 

Expression of C1QA:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 C1QA 712 218232_at 0.2372 0.8644
GSE20347 C1QA 712 218232_at 0.6413 0.0185
GSE23400 C1QA 712 218232_at 0.6245 0.0004
GSE26886 C1QA 712 218232_at 0.3249 0.4177
GSE29001 C1QA 712 218232_at 0.8504 0.0275
GSE38129 C1QA 712 218232_at 0.4792 0.1683
GSE45670 C1QA 712 218232_at -0.2327 0.5164
GSE53622 C1QA 712 57451 0.5822 0.0024
GSE53624 C1QA 712 57451 0.8914 0.0000
GSE63941 C1QA 712 218232_at -0.0700 0.5886
GSE77861 C1QA 712 218232_at 0.4469 0.0880
GSE97050 C1QA 712 A_24_P222655 0.6579 0.2921
SRP007169 C1QA 712 RNAseq 1.8422 0.0114
SRP008496 C1QA 712 RNAseq 1.3944 0.0025
SRP064894 C1QA 712 RNAseq 0.6603 0.1386
SRP133303 C1QA 712 RNAseq 0.7533 0.0621
SRP159526 C1QA 712 RNAseq 0.4742 0.4266
SRP193095 C1QA 712 RNAseq 0.7208 0.0160
SRP219564 C1QA 712 RNAseq 1.8081 0.0469
TCGA C1QA 712 RNAseq 0.2875 0.0310

Upregulated datasets: 3; Downregulated datasets: 0.  

 

Survival by C1QA expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of C1QA:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 C1QA 712 0 5 25
GSE20123 C1QA 712 0 4 26
GSE43470 C1QA 712 2 6 35
GSE46452 C1QA 712 5 1 53
GSE47630 C1QA 712 8 3 29
GSE54993 C1QA 712 2 1 67
GSE54994 C1QA 712 11 4 38
GSE60625 C1QA 712 0 0 11
GSE74703 C1QA 712 1 4 31
GSE74704 C1QA 712 0 0 20
TCGA C1QA 712 10 23 63

Total number of gains: 39; Total number of losses: 51; Total Number of normals: 398.  

 

Somatic mutations of C1QA:

 

Generating mutation plots.

 

Highly correlated genes for C1QA:

 

Showing top 20/879 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
C1QAC1QB0.90868312012
C1QATYROBP0.86002712012
C1QAC1QC0.844862808
C1QACD140.82283512012
C1QAFCGR3A0.820204303
C1QARASSF40.799876606
C1QACERKL0.797653303
C1QAC19orf380.797157303
C1QAMS4A4A0.79016611010
C1QALAPTM50.78154412012
C1QAMS4A70.774921404
C1QAC3AR10.76800512010
C1QACD163L10.765402404
C1QATFEC0.76495610010
C1QALRRC250.764753303
C1QAMS4A6A0.75380311011
C1QACD530.75361210010
C1QAITGB20.75212811011
C1QAAIF10.75139212011
C1QACSF1R0.75130512011

For details and further investigation, click here