| Full name: CD163 molecule | Alias Symbol: M130|MM130|SCARI1 | ||
| Type: protein-coding gene | Cytoband: 12p13.31 | ||
| Entrez ID: 9332 | HGNC ID: HGNC:1631 | Ensembl Gene: ENSG00000177575 | OMIM ID: 605545 |
| Drug and gene relationship at DGIdb | |||
Expression of CD163:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CD163 | 9332 | 215049_x_at | -0.1510 | 0.9385 | |
| GSE20347 | CD163 | 9332 | 215049_x_at | 1.1595 | 0.0001 | |
| GSE23400 | CD163 | 9332 | 203645_s_at | 0.6952 | 0.0000 | |
| GSE26886 | CD163 | 9332 | 215049_x_at | 1.6184 | 0.0027 | |
| GSE29001 | CD163 | 9332 | 215049_x_at | 1.5105 | 0.0041 | |
| GSE38129 | CD163 | 9332 | 203645_s_at | 0.8417 | 0.0191 | |
| GSE45670 | CD163 | 9332 | 215049_x_at | -0.9046 | 0.0636 | |
| GSE53622 | CD163 | 9332 | 15335 | 0.3432 | 0.1582 | |
| GSE53624 | CD163 | 9332 | 15335 | 1.0496 | 0.0000 | |
| GSE63941 | CD163 | 9332 | 203645_s_at | -0.0260 | 0.8821 | |
| GSE77861 | CD163 | 9332 | 203645_s_at | 0.2580 | 0.1581 | |
| GSE97050 | CD163 | 9332 | A_23_P33723 | 0.8470 | 0.1891 | |
| SRP007169 | CD163 | 9332 | RNAseq | 4.0272 | 0.0000 | |
| SRP008496 | CD163 | 9332 | RNAseq | 3.6849 | 0.0000 | |
| SRP064894 | CD163 | 9332 | RNAseq | 1.3247 | 0.0059 | |
| SRP133303 | CD163 | 9332 | RNAseq | 0.6802 | 0.1229 | |
| SRP159526 | CD163 | 9332 | RNAseq | 1.3435 | 0.0568 | |
| SRP193095 | CD163 | 9332 | RNAseq | 1.4648 | 0.0000 | |
| SRP219564 | CD163 | 9332 | RNAseq | 1.4321 | 0.0523 | |
| TCGA | CD163 | 9332 | RNAseq | -0.1624 | 0.3252 |
Upregulated datasets: 8; Downregulated datasets: 0.
Survival by CD163 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CD163:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CD163 | 9332 | 6 | 3 | 21 | |
| GSE20123 | CD163 | 9332 | 6 | 3 | 21 | |
| GSE43470 | CD163 | 9332 | 8 | 3 | 32 | |
| GSE46452 | CD163 | 9332 | 10 | 1 | 48 | |
| GSE47630 | CD163 | 9332 | 12 | 2 | 26 | |
| GSE54993 | CD163 | 9332 | 1 | 10 | 59 | |
| GSE54994 | CD163 | 9332 | 10 | 2 | 41 | |
| GSE60625 | CD163 | 9332 | 0 | 1 | 10 | |
| GSE74703 | CD163 | 9332 | 7 | 2 | 27 | |
| GSE74704 | CD163 | 9332 | 4 | 2 | 14 | |
| TCGA | CD163 | 9332 | 40 | 6 | 50 |
Total number of gains: 104; Total number of losses: 35; Total Number of normals: 349.
Somatic mutations of CD163:
Generating mutation plots.
Highly correlated genes for CD163:
Showing top 20/1244 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CD163 | MS4A4A | 0.850745 | 11 | 0 | 11 |
| CD163 | FCGR3A | 0.833436 | 3 | 0 | 3 |
| CD163 | MRC1 | 0.828041 | 11 | 0 | 11 |
| CD163 | FCER1G | 0.824101 | 11 | 0 | 11 |
| CD163 | C3AR1 | 0.805313 | 11 | 0 | 11 |
| CD163 | TYROBP | 0.790859 | 12 | 0 | 12 |
| CD163 | C19orf38 | 0.786661 | 3 | 0 | 3 |
| CD163 | MS4A6A | 0.773685 | 9 | 0 | 9 |
| CD163 | MPEG1 | 0.773079 | 5 | 0 | 5 |
| CD163 | FCGR2A | 0.765519 | 12 | 0 | 11 |
| CD163 | TMEM176B | 0.765172 | 10 | 0 | 9 |
| CD163 | C1QB | 0.762726 | 13 | 0 | 12 |
| CD163 | SRGN | 0.756016 | 12 | 0 | 12 |
| CD163 | PIK3AP1 | 0.752382 | 5 | 0 | 5 |
| CD163 | VSIG4 | 0.750448 | 12 | 0 | 11 |
| CD163 | ITGAM | 0.750335 | 9 | 0 | 9 |
| CD163 | CYBB | 0.748489 | 11 | 0 | 11 |
| CD163 | IL2RA | 0.745942 | 4 | 0 | 4 |
| CD163 | CCR1 | 0.744645 | 10 | 0 | 10 |
| CD163 | GPR141 | 0.743778 | 3 | 0 | 3 |
For details and further investigation, click here
