| Full name: natural killer cell granule protein 7 | Alias Symbol: GIG1|GMP-17 | ||
| Type: protein-coding gene | Cytoband: 19q13.41 | ||
| Entrez ID: 4818 | HGNC ID: HGNC:7830 | Ensembl Gene: ENSG00000105374 | OMIM ID: 606008 |
| Drug and gene relationship at DGIdb | |||
Expression of NKG7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NKG7 | 4818 | 213915_at | 0.6531 | 0.4976 | |
| GSE20347 | NKG7 | 4818 | 213915_at | -0.1504 | 0.3804 | |
| GSE23400 | NKG7 | 4818 | 213915_at | 0.0296 | 0.6559 | |
| GSE26886 | NKG7 | 4818 | 213915_at | 0.1882 | 0.4156 | |
| GSE29001 | NKG7 | 4818 | 213915_at | 0.0601 | 0.7678 | |
| GSE38129 | NKG7 | 4818 | 213915_at | -0.1182 | 0.5700 | |
| GSE45670 | NKG7 | 4818 | 213915_at | -0.0559 | 0.8623 | |
| GSE53622 | NKG7 | 4818 | 43592 | 0.3508 | 0.0814 | |
| GSE53624 | NKG7 | 4818 | 43592 | 0.0758 | 0.6998 | |
| GSE63941 | NKG7 | 4818 | 213915_at | -0.0049 | 0.9792 | |
| GSE77861 | NKG7 | 4818 | 213915_at | -0.2457 | 0.1673 | |
| GSE97050 | NKG7 | 4818 | A_23_P119042 | 0.4853 | 0.3287 | |
| SRP064894 | NKG7 | 4818 | RNAseq | 0.1522 | 0.6973 | |
| SRP133303 | NKG7 | 4818 | RNAseq | -0.0566 | 0.8918 | |
| SRP159526 | NKG7 | 4818 | RNAseq | -0.4780 | 0.5787 | |
| SRP193095 | NKG7 | 4818 | RNAseq | -0.2933 | 0.2312 | |
| SRP219564 | NKG7 | 4818 | RNAseq | 1.7649 | 0.0023 | |
| TCGA | NKG7 | 4818 | RNAseq | 0.4452 | 0.1065 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by NKG7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NKG7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NKG7 | 4818 | 3 | 4 | 23 | |
| GSE20123 | NKG7 | 4818 | 3 | 3 | 24 | |
| GSE43470 | NKG7 | 4818 | 3 | 12 | 28 | |
| GSE46452 | NKG7 | 4818 | 45 | 1 | 13 | |
| GSE47630 | NKG7 | 4818 | 9 | 6 | 25 | |
| GSE54993 | NKG7 | 4818 | 17 | 4 | 49 | |
| GSE54994 | NKG7 | 4818 | 4 | 14 | 35 | |
| GSE60625 | NKG7 | 4818 | 9 | 0 | 2 | |
| GSE74703 | NKG7 | 4818 | 3 | 8 | 25 | |
| GSE74704 | NKG7 | 4818 | 3 | 1 | 16 | |
| TCGA | NKG7 | 4818 | 14 | 19 | 63 |
Total number of gains: 113; Total number of losses: 72; Total Number of normals: 303.
Somatic mutations of NKG7:
Generating mutation plots.
Highly correlated genes for NKG7:
Showing top 20/440 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NKG7 | GZMA | 0.763021 | 11 | 0 | 10 |
| NKG7 | SAMD3 | 0.755698 | 6 | 0 | 5 |
| NKG7 | CD226 | 0.74628 | 8 | 0 | 8 |
| NKG7 | TNFSF8 | 0.730133 | 5 | 0 | 5 |
| NKG7 | CD3D | 0.728885 | 12 | 0 | 10 |
| NKG7 | CD2 | 0.723731 | 12 | 0 | 12 |
| NKG7 | SCML4 | 0.723058 | 4 | 0 | 4 |
| NKG7 | SNX20 | 0.722829 | 6 | 0 | 6 |
| NKG7 | CST7 | 0.717072 | 11 | 0 | 11 |
| NKG7 | NCKAP1L | 0.71072 | 9 | 0 | 8 |
| NKG7 | LRRC25 | 0.710314 | 3 | 0 | 3 |
| NKG7 | TIGIT | 0.707109 | 6 | 0 | 5 |
| NKG7 | ACAP1 | 0.697864 | 7 | 0 | 5 |
| NKG7 | GZMB | 0.695699 | 11 | 0 | 10 |
| NKG7 | GIMAP5 | 0.695648 | 4 | 0 | 4 |
| NKG7 | CCR5 | 0.694783 | 9 | 0 | 8 |
| NKG7 | CD163L1 | 0.694585 | 3 | 0 | 3 |
| NKG7 | CCL5 | 0.690237 | 12 | 0 | 11 |
| NKG7 | CD96 | 0.689425 | 10 | 0 | 8 |
| NKG7 | CD248 | 0.688887 | 3 | 0 | 3 |
For details and further investigation, click here
