| Full name: leucine rich repeat containing 27 | Alias Symbol: KIAA1674 | ||
| Type: protein-coding gene | Cytoband: 10q26.3 | ||
| Entrez ID: 80313 | HGNC ID: HGNC:29346 | Ensembl Gene: ENSG00000148814 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LRRC27:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRC27 | 80313 | 1558484_s_at | -0.0305 | 0.9443 | |
| GSE26886 | LRRC27 | 80313 | 228886_at | 0.3087 | 0.1734 | |
| GSE45670 | LRRC27 | 80313 | 1558484_s_at | 0.3171 | 0.0076 | |
| GSE53622 | LRRC27 | 80313 | 144489 | 0.4934 | 0.0000 | |
| GSE53624 | LRRC27 | 80313 | 144489 | 0.2529 | 0.0059 | |
| GSE63941 | LRRC27 | 80313 | 1558484_s_at | 0.0200 | 0.9503 | |
| GSE77861 | LRRC27 | 80313 | 1558484_s_at | -0.0528 | 0.6538 | |
| GSE97050 | LRRC27 | 80313 | A_33_P3229873 | 0.2304 | 0.3582 | |
| SRP007169 | LRRC27 | 80313 | RNAseq | -0.5078 | 0.4930 | |
| SRP064894 | LRRC27 | 80313 | RNAseq | 0.0970 | 0.6335 | |
| SRP133303 | LRRC27 | 80313 | RNAseq | -0.1251 | 0.3126 | |
| SRP159526 | LRRC27 | 80313 | RNAseq | 0.0594 | 0.8536 | |
| SRP193095 | LRRC27 | 80313 | RNAseq | -0.0765 | 0.6505 | |
| SRP219564 | LRRC27 | 80313 | RNAseq | -0.0865 | 0.8419 | |
| TCGA | LRRC27 | 80313 | RNAseq | -0.3890 | 0.0009 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LRRC27 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRRC27:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRC27 | 80313 | 2 | 8 | 20 | |
| GSE20123 | LRRC27 | 80313 | 2 | 9 | 19 | |
| GSE43470 | LRRC27 | 80313 | 0 | 9 | 34 | |
| GSE46452 | LRRC27 | 80313 | 1 | 11 | 47 | |
| GSE47630 | LRRC27 | 80313 | 4 | 13 | 23 | |
| GSE54993 | LRRC27 | 80313 | 7 | 1 | 62 | |
| GSE54994 | LRRC27 | 80313 | 1 | 9 | 43 | |
| GSE60625 | LRRC27 | 80313 | 0 | 0 | 11 | |
| GSE74703 | LRRC27 | 80313 | 0 | 6 | 30 | |
| GSE74704 | LRRC27 | 80313 | 2 | 4 | 14 | |
| TCGA | LRRC27 | 80313 | 7 | 28 | 61 |
Total number of gains: 26; Total number of losses: 98; Total Number of normals: 364.
Somatic mutations of LRRC27:
Generating mutation plots.
Highly correlated genes for LRRC27:
Showing top 20/116 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRC27 | ZNF761 | 0.751983 | 3 | 0 | 3 |
| LRRC27 | KCTD19 | 0.694321 | 4 | 0 | 4 |
| LRRC27 | RAX2 | 0.691385 | 3 | 0 | 3 |
| LRRC27 | GJD4 | 0.687657 | 4 | 0 | 4 |
| LRRC27 | GPR25 | 0.684011 | 3 | 0 | 3 |
| LRRC27 | GFAP | 0.683325 | 3 | 0 | 3 |
| LRRC27 | SUN5 | 0.667324 | 4 | 0 | 4 |
| LRRC27 | C16orf86 | 0.666623 | 4 | 0 | 4 |
| LRRC27 | SPRED3 | 0.662158 | 4 | 0 | 4 |
| LRRC27 | TMEM63B | 0.660037 | 3 | 0 | 3 |
| LRRC27 | RASL10B | 0.655538 | 3 | 0 | 3 |
| LRRC27 | CREB3L3 | 0.65139 | 3 | 0 | 3 |
| LRRC27 | KRTAP3-1 | 0.64605 | 4 | 0 | 4 |
| LRRC27 | PNPLA7 | 0.641542 | 3 | 0 | 3 |
| LRRC27 | RNASE3 | 0.639467 | 3 | 0 | 3 |
| LRRC27 | OR2C3 | 0.636137 | 3 | 0 | 3 |
| LRRC27 | KIRREL3-AS3 | 0.635977 | 3 | 0 | 3 |
| LRRC27 | GNB3 | 0.63074 | 4 | 0 | 3 |
| LRRC27 | MNX1 | 0.628158 | 3 | 0 | 3 |
| LRRC27 | NCKAP5L | 0.627658 | 4 | 0 | 3 |
For details and further investigation, click here
