| Full name: leucine rich repeat containing 36 | Alias Symbol: FLJ11004 | ||
| Type: protein-coding gene | Cytoband: 16q22.1 | ||
| Entrez ID: 55282 | HGNC ID: HGNC:25615 | Ensembl Gene: ENSG00000159708 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LRRC36:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRC36 | 55282 | 220003_at | -0.0777 | 0.7147 | |
| GSE20347 | LRRC36 | 55282 | 220003_at | -0.0267 | 0.7360 | |
| GSE23400 | LRRC36 | 55282 | 220003_at | -0.1149 | 0.0014 | |
| GSE26886 | LRRC36 | 55282 | 220003_at | -0.0062 | 0.9707 | |
| GSE29001 | LRRC36 | 55282 | 220003_at | -0.0434 | 0.7595 | |
| GSE38129 | LRRC36 | 55282 | 220003_at | -0.0282 | 0.6763 | |
| GSE45670 | LRRC36 | 55282 | 220003_at | 0.0398 | 0.6571 | |
| GSE53622 | LRRC36 | 55282 | 77683 | 0.0948 | 0.2683 | |
| GSE53624 | LRRC36 | 55282 | 77683 | 0.1642 | 0.0087 | |
| GSE63941 | LRRC36 | 55282 | 220003_at | -0.0046 | 0.9819 | |
| GSE77861 | LRRC36 | 55282 | 220003_at | -0.1005 | 0.2714 | |
| GSE97050 | LRRC36 | 55282 | A_23_P118042 | -0.1766 | 0.3799 | |
| TCGA | LRRC36 | 55282 | RNAseq | -1.6380 | 0.0015 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by LRRC36 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRRC36:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRC36 | 55282 | 9 | 2 | 19 | |
| GSE20123 | LRRC36 | 55282 | 9 | 2 | 19 | |
| GSE43470 | LRRC36 | 55282 | 1 | 9 | 33 | |
| GSE46452 | LRRC36 | 55282 | 38 | 1 | 20 | |
| GSE47630 | LRRC36 | 55282 | 10 | 8 | 22 | |
| GSE54993 | LRRC36 | 55282 | 2 | 4 | 64 | |
| GSE54994 | LRRC36 | 55282 | 8 | 10 | 35 | |
| GSE60625 | LRRC36 | 55282 | 4 | 0 | 7 | |
| GSE74703 | LRRC36 | 55282 | 1 | 6 | 29 | |
| GSE74704 | LRRC36 | 55282 | 5 | 1 | 14 | |
| TCGA | LRRC36 | 55282 | 29 | 12 | 55 |
Total number of gains: 116; Total number of losses: 55; Total Number of normals: 317.
Somatic mutations of LRRC36:
Generating mutation plots.
Highly correlated genes for LRRC36:
Showing top 20/445 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRC36 | CAPZB | 0.773565 | 3 | 0 | 3 |
| LRRC36 | EIF1AY | 0.743735 | 3 | 0 | 3 |
| LRRC36 | KDM5D | 0.741293 | 3 | 0 | 3 |
| LRRC36 | USP9Y | 0.728421 | 3 | 0 | 3 |
| LRRC36 | BCAS4 | 0.72585 | 3 | 0 | 3 |
| LRRC36 | SPSB4 | 0.714941 | 4 | 0 | 4 |
| LRRC36 | ZBTB10 | 0.710751 | 3 | 0 | 3 |
| LRRC36 | NKX2-5 | 0.709104 | 3 | 0 | 3 |
| LRRC36 | RNF31 | 0.708661 | 4 | 0 | 4 |
| LRRC36 | SFTPA2 | 0.707457 | 3 | 0 | 3 |
| LRRC36 | GDF9 | 0.70516 | 4 | 0 | 3 |
| LRRC36 | SAMD10 | 0.697646 | 3 | 0 | 3 |
| LRRC36 | KCND3 | 0.694989 | 4 | 0 | 4 |
| LRRC36 | NELL1 | 0.691745 | 3 | 0 | 3 |
| LRRC36 | OR2T33 | 0.689735 | 3 | 0 | 3 |
| LRRC36 | SLC4A5 | 0.684212 | 3 | 0 | 3 |
| LRRC36 | ARHGEF15 | 0.683375 | 6 | 0 | 5 |
| LRRC36 | ABR | 0.683164 | 3 | 0 | 3 |
| LRRC36 | ADAMTS10 | 0.682136 | 3 | 0 | 3 |
| LRRC36 | KRTAP21-2 | 0.681034 | 3 | 0 | 3 |
For details and further investigation, click here
