| Full name: leucine rich repeat containing 41 | Alias Symbol: MUF1 | ||
| Type: protein-coding gene | Cytoband: 1p34.1-p33 | ||
| Entrez ID: 10489 | HGNC ID: HGNC:16917 | Ensembl Gene: ENSG00000132128 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LRRC41:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRC41 | 10489 | 201932_at | 0.1642 | 0.7831 | |
| GSE20347 | LRRC41 | 10489 | 201932_at | -0.0595 | 0.7669 | |
| GSE23400 | LRRC41 | 10489 | 201932_at | 0.0935 | 0.0735 | |
| GSE26886 | LRRC41 | 10489 | 201932_at | -0.0857 | 0.6394 | |
| GSE29001 | LRRC41 | 10489 | 201932_at | -0.2475 | 0.2531 | |
| GSE38129 | LRRC41 | 10489 | 201932_at | 0.0704 | 0.6529 | |
| GSE45670 | LRRC41 | 10489 | 201932_at | 0.0455 | 0.7554 | |
| GSE53622 | LRRC41 | 10489 | 30049 | -0.0144 | 0.8332 | |
| GSE53624 | LRRC41 | 10489 | 30049 | 0.0303 | 0.7008 | |
| GSE63941 | LRRC41 | 10489 | 201932_at | 0.2030 | 0.5406 | |
| GSE77861 | LRRC41 | 10489 | 201932_at | 0.1646 | 0.6300 | |
| GSE97050 | LRRC41 | 10489 | A_33_P3289222 | -0.0395 | 0.8469 | |
| SRP007169 | LRRC41 | 10489 | RNAseq | -1.3579 | 0.0029 | |
| SRP008496 | LRRC41 | 10489 | RNAseq | -1.1770 | 0.0000 | |
| SRP064894 | LRRC41 | 10489 | RNAseq | -0.1149 | 0.4495 | |
| SRP133303 | LRRC41 | 10489 | RNAseq | 0.1408 | 0.1532 | |
| SRP159526 | LRRC41 | 10489 | RNAseq | 0.1159 | 0.5096 | |
| SRP193095 | LRRC41 | 10489 | RNAseq | 0.0650 | 0.5361 | |
| SRP219564 | LRRC41 | 10489 | RNAseq | 0.4551 | 0.2317 | |
| TCGA | LRRC41 | 10489 | RNAseq | 0.0113 | 0.8014 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by LRRC41 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LRRC41:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRC41 | 10489 | 4 | 3 | 23 | |
| GSE20123 | LRRC41 | 10489 | 4 | 2 | 24 | |
| GSE43470 | LRRC41 | 10489 | 5 | 2 | 36 | |
| GSE46452 | LRRC41 | 10489 | 2 | 1 | 56 | |
| GSE47630 | LRRC41 | 10489 | 8 | 4 | 28 | |
| GSE54993 | LRRC41 | 10489 | 0 | 1 | 69 | |
| GSE54994 | LRRC41 | 10489 | 11 | 2 | 40 | |
| GSE60625 | LRRC41 | 10489 | 0 | 0 | 11 | |
| GSE74703 | LRRC41 | 10489 | 4 | 1 | 31 | |
| GSE74704 | LRRC41 | 10489 | 2 | 0 | 18 | |
| TCGA | LRRC41 | 10489 | 10 | 17 | 69 |
Total number of gains: 50; Total number of losses: 33; Total Number of normals: 405.
Somatic mutations of LRRC41:
Generating mutation plots.
Highly correlated genes for LRRC41:
Showing top 20/281 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRC41 | TMEM205 | 0.844978 | 3 | 0 | 3 |
| LRRC41 | TRIM28 | 0.799418 | 3 | 0 | 3 |
| LRRC41 | MRPL38 | 0.788227 | 3 | 0 | 3 |
| LRRC41 | TMCO4 | 0.784692 | 3 | 0 | 3 |
| LRRC41 | PRKCSH | 0.760143 | 3 | 0 | 3 |
| LRRC41 | PTPRU | 0.754773 | 3 | 0 | 3 |
| LRRC41 | SMG9 | 0.754364 | 3 | 0 | 3 |
| LRRC41 | SPHK2 | 0.753433 | 3 | 0 | 3 |
| LRRC41 | NUB1 | 0.750365 | 3 | 0 | 3 |
| LRRC41 | RNF207 | 0.746977 | 4 | 0 | 4 |
| LRRC41 | UPF1 | 0.744294 | 3 | 0 | 3 |
| LRRC41 | YLPM1 | 0.738387 | 3 | 0 | 3 |
| LRRC41 | ZNF766 | 0.736143 | 3 | 0 | 3 |
| LRRC41 | CHID1 | 0.735955 | 3 | 0 | 3 |
| LRRC41 | RRAGB | 0.735798 | 3 | 0 | 3 |
| LRRC41 | CRKL | 0.734936 | 3 | 0 | 3 |
| LRRC41 | AP2A2 | 0.732767 | 3 | 0 | 3 |
| LRRC41 | KBTBD4 | 0.720431 | 3 | 0 | 3 |
| LRRC41 | ASPSCR1 | 0.717909 | 3 | 0 | 3 |
| LRRC41 | CDKAL1 | 0.716789 | 3 | 0 | 3 |
For details and further investigation, click here
