| Full name: CDK5 regulatory subunit associated protein 1 like 1 | Alias Symbol: FLJ20342 | ||
| Type: protein-coding gene | Cytoband: 6p22.3 | ||
| Entrez ID: 54901 | HGNC ID: HGNC:21050 | Ensembl Gene: ENSG00000145996 | OMIM ID: 611259 |
| Drug and gene relationship at DGIdb | |||
Expression of CDKAL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDKAL1 | 54901 | 214877_at | -0.0045 | 0.9979 | |
| GSE20347 | CDKAL1 | 54901 | 214877_at | 0.1792 | 0.5155 | |
| GSE23400 | CDKAL1 | 54901 | 214877_at | 0.1734 | 0.0068 | |
| GSE26886 | CDKAL1 | 54901 | 214877_at | -0.5172 | 0.0050 | |
| GSE29001 | CDKAL1 | 54901 | 214877_at | 0.0515 | 0.8678 | |
| GSE38129 | CDKAL1 | 54901 | 214877_at | 0.2287 | 0.3807 | |
| GSE45670 | CDKAL1 | 54901 | 214877_at | 0.1091 | 0.8165 | |
| GSE53622 | CDKAL1 | 54901 | 31476 | 0.1925 | 0.0029 | |
| GSE53624 | CDKAL1 | 54901 | 24396 | 0.2131 | 0.0055 | |
| GSE63941 | CDKAL1 | 54901 | 214877_at | 0.7466 | 0.3209 | |
| GSE77861 | CDKAL1 | 54901 | 214877_at | -0.0204 | 0.9468 | |
| GSE97050 | CDKAL1 | 54901 | A_23_P44781 | 0.2652 | 0.5065 | |
| SRP007169 | CDKAL1 | 54901 | RNAseq | 0.0499 | 0.8973 | |
| SRP008496 | CDKAL1 | 54901 | RNAseq | 0.2224 | 0.3428 | |
| SRP064894 | CDKAL1 | 54901 | RNAseq | 0.3783 | 0.0184 | |
| SRP133303 | CDKAL1 | 54901 | RNAseq | 0.1271 | 0.4487 | |
| SRP159526 | CDKAL1 | 54901 | RNAseq | 0.5404 | 0.0874 | |
| SRP193095 | CDKAL1 | 54901 | RNAseq | 0.0691 | 0.4171 | |
| SRP219564 | CDKAL1 | 54901 | RNAseq | 0.1890 | 0.4706 | |
| TCGA | CDKAL1 | 54901 | RNAseq | 0.0750 | 0.3478 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CDKAL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDKAL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDKAL1 | 54901 | 4 | 4 | 22 | |
| GSE20123 | CDKAL1 | 54901 | 4 | 4 | 22 | |
| GSE43470 | CDKAL1 | 54901 | 11 | 0 | 32 | |
| GSE46452 | CDKAL1 | 54901 | 3 | 9 | 47 | |
| GSE47630 | CDKAL1 | 54901 | 11 | 4 | 25 | |
| GSE54993 | CDKAL1 | 54901 | 1 | 1 | 68 | |
| GSE54994 | CDKAL1 | 54901 | 12 | 3 | 38 | |
| GSE60625 | CDKAL1 | 54901 | 0 | 1 | 10 | |
| GSE74703 | CDKAL1 | 54901 | 10 | 0 | 26 | |
| GSE74704 | CDKAL1 | 54901 | 1 | 1 | 18 | |
| TCGA | CDKAL1 | 54901 | 19 | 26 | 51 |
Total number of gains: 76; Total number of losses: 53; Total Number of normals: 359.
Somatic mutations of CDKAL1:
Generating mutation plots.
Highly correlated genes for CDKAL1:
Showing top 20/64 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDKAL1 | LRRC41 | 0.716789 | 3 | 0 | 3 |
| CDKAL1 | RNF113A | 0.693967 | 3 | 0 | 3 |
| CDKAL1 | TPI1 | 0.688473 | 4 | 0 | 3 |
| CDKAL1 | TPM4 | 0.683922 | 3 | 0 | 3 |
| CDKAL1 | DNAAF2 | 0.654847 | 3 | 0 | 3 |
| CDKAL1 | TRAPPC6B | 0.652303 | 3 | 0 | 3 |
| CDKAL1 | WDR77 | 0.645609 | 4 | 0 | 3 |
| CDKAL1 | SLC25A5 | 0.645289 | 3 | 0 | 3 |
| CDKAL1 | NOTCH2 | 0.641842 | 3 | 0 | 3 |
| CDKAL1 | ARSG | 0.641367 | 3 | 0 | 3 |
| CDKAL1 | ACOX1 | 0.641344 | 3 | 0 | 3 |
| CDKAL1 | TAF7 | 0.63113 | 3 | 0 | 3 |
| CDKAL1 | PRKRA | 0.63091 | 3 | 0 | 3 |
| CDKAL1 | SLC25A11 | 0.630552 | 3 | 0 | 3 |
| CDKAL1 | HIPK2 | 0.629712 | 3 | 0 | 3 |
| CDKAL1 | DHDH | 0.624529 | 3 | 0 | 3 |
| CDKAL1 | SENP8 | 0.624412 | 3 | 0 | 3 |
| CDKAL1 | PARG | 0.621638 | 4 | 0 | 3 |
| CDKAL1 | PCSK1 | 0.620396 | 3 | 0 | 3 |
| CDKAL1 | SRRM1 | 0.61736 | 5 | 0 | 4 |
For details and further investigation, click here
