| Full name: leucine rich repeats and death domain containing 1 | Alias Symbol: IMAGE:4798971 | ||
| Type: protein-coding gene | Cytoband: 7q21.2 | ||
| Entrez ID: 401387 | HGNC ID: HGNC:34300 | Ensembl Gene: ENSG00000240720 | OMIM ID: |
Expression of LRRD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LRRD1 | 401387 | 1569783_at | -0.0803 | 0.6876 | |
| GSE26886 | LRRD1 | 401387 | 1569783_at | 0.0647 | 0.4184 | |
| GSE45670 | LRRD1 | 401387 | 1569783_at | 0.0002 | 0.9985 | |
| GSE53622 | LRRD1 | 401387 | 71206 | -0.0455 | 0.6032 | |
| GSE53624 | LRRD1 | 401387 | 71206 | -0.3210 | 0.1373 | |
| GSE63941 | LRRD1 | 401387 | 1569783_at | -0.0023 | 0.9846 | |
| GSE77861 | LRRD1 | 401387 | 1569783_at | -0.0568 | 0.5706 | |
| GSE97050 | LRRD1 | 401387 | A_33_P3420446 | 0.0314 | 0.9135 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LRRD1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of LRRD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LRRD1 | 401387 | 13 | 0 | 17 | |
| GSE20123 | LRRD1 | 401387 | 13 | 0 | 17 | |
| GSE43470 | LRRD1 | 401387 | 6 | 1 | 36 | |
| GSE46452 | LRRD1 | 401387 | 11 | 0 | 48 | |
| GSE47630 | LRRD1 | 401387 | 9 | 2 | 29 | |
| GSE54993 | LRRD1 | 401387 | 1 | 8 | 61 | |
| GSE54994 | LRRD1 | 401387 | 16 | 2 | 35 | |
| GSE60625 | LRRD1 | 401387 | 0 | 0 | 11 | |
| GSE74703 | LRRD1 | 401387 | 5 | 1 | 30 | |
| GSE74704 | LRRD1 | 401387 | 9 | 0 | 11 | |
| TCGA | LRRD1 | 401387 | 56 | 4 | 36 |
Total number of gains: 139; Total number of losses: 18; Total Number of normals: 331.
Somatic mutations of LRRD1:
Generating mutation plots.
Highly correlated genes for LRRD1:
Showing top 20/82 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LRRD1 | PRSS36 | 0.868573 | 3 | 0 | 3 |
| LRRD1 | BARHL1 | 0.777974 | 3 | 0 | 3 |
| LRRD1 | KRTAP19-2 | 0.771491 | 3 | 0 | 3 |
| LRRD1 | THRAP3 | 0.758891 | 3 | 0 | 3 |
| LRRD1 | AFTPH | 0.722228 | 3 | 0 | 3 |
| LRRD1 | YPEL2 | 0.719088 | 3 | 0 | 3 |
| LRRD1 | SMPD1 | 0.71421 | 4 | 0 | 4 |
| LRRD1 | TMEM167B | 0.71377 | 3 | 0 | 3 |
| LRRD1 | BECN1 | 0.706704 | 3 | 0 | 3 |
| LRRD1 | SNX1 | 0.6999 | 3 | 0 | 3 |
| LRRD1 | ATP6V0E1 | 0.694245 | 3 | 0 | 3 |
| LRRD1 | TJP1 | 0.693463 | 3 | 0 | 3 |
| LRRD1 | PARP4 | 0.691715 | 3 | 0 | 3 |
| LRRD1 | CHMP2A | 0.690826 | 3 | 0 | 3 |
| LRRD1 | GOLGB1 | 0.686841 | 3 | 0 | 3 |
| LRRD1 | RECQL5 | 0.682762 | 3 | 0 | 3 |
| LRRD1 | OSCAR | 0.682488 | 4 | 0 | 4 |
| LRRD1 | LCE1E | 0.680152 | 4 | 0 | 3 |
| LRRD1 | LINC01405 | 0.67881 | 3 | 0 | 3 |
| LRRD1 | VPS25 | 0.67847 | 3 | 0 | 3 |
For details and further investigation, click here
