| Full name: RecQ like helicase 5 | Alias Symbol: RecQ5|FLJ90603 | ||
| Type: protein-coding gene | Cytoband: 17q25 | ||
| Entrez ID: 9400 | HGNC ID: HGNC:9950 | Ensembl Gene: ENSG00000108469 | OMIM ID: 603781 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of RECQL5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RECQL5 | 9400 | 221686_s_at | -0.4346 | 0.1236 | |
| GSE20347 | RECQL5 | 9400 | 221686_s_at | -0.5025 | 0.0000 | |
| GSE23400 | RECQL5 | 9400 | 221686_s_at | -0.4984 | 0.0000 | |
| GSE26886 | RECQL5 | 9400 | 221686_s_at | -1.0040 | 0.0000 | |
| GSE29001 | RECQL5 | 9400 | 221686_s_at | -0.6345 | 0.0068 | |
| GSE38129 | RECQL5 | 9400 | 221686_s_at | -0.4505 | 0.0000 | |
| GSE45670 | RECQL5 | 9400 | 221686_s_at | -0.2034 | 0.1600 | |
| GSE53622 | RECQL5 | 9400 | 29622 | -0.8507 | 0.0000 | |
| GSE53624 | RECQL5 | 9400 | 29622 | -0.9561 | 0.0000 | |
| GSE63941 | RECQL5 | 9400 | 221686_s_at | 0.8848 | 0.0007 | |
| GSE77861 | RECQL5 | 9400 | 221686_s_at | -0.2420 | 0.3741 | |
| GSE97050 | RECQL5 | 9400 | A_33_P3268974 | 0.0067 | 0.9790 | |
| SRP007169 | RECQL5 | 9400 | RNAseq | -1.3335 | 0.0011 | |
| SRP008496 | RECQL5 | 9400 | RNAseq | -1.7263 | 0.0000 | |
| SRP064894 | RECQL5 | 9400 | RNAseq | -0.6241 | 0.0025 | |
| SRP133303 | RECQL5 | 9400 | RNAseq | -0.4483 | 0.0438 | |
| SRP159526 | RECQL5 | 9400 | RNAseq | -0.3665 | 0.4129 | |
| SRP193095 | RECQL5 | 9400 | RNAseq | -0.6674 | 0.0000 | |
| SRP219564 | RECQL5 | 9400 | RNAseq | -0.1473 | 0.8129 | |
| TCGA | RECQL5 | 9400 | RNAseq | -0.0755 | 0.1653 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by RECQL5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RECQL5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RECQL5 | 9400 | 7 | 2 | 21 | |
| GSE20123 | RECQL5 | 9400 | 7 | 2 | 21 | |
| GSE43470 | RECQL5 | 9400 | 5 | 3 | 35 | |
| GSE46452 | RECQL5 | 9400 | 34 | 0 | 25 | |
| GSE47630 | RECQL5 | 9400 | 8 | 1 | 31 | |
| GSE54993 | RECQL5 | 9400 | 2 | 5 | 63 | |
| GSE54994 | RECQL5 | 9400 | 10 | 4 | 39 | |
| GSE60625 | RECQL5 | 9400 | 6 | 0 | 5 | |
| GSE74703 | RECQL5 | 9400 | 5 | 1 | 30 | |
| GSE74704 | RECQL5 | 9400 | 5 | 1 | 14 | |
| TCGA | RECQL5 | 9400 | 32 | 9 | 55 |
Total number of gains: 121; Total number of losses: 28; Total Number of normals: 339.
Somatic mutations of RECQL5:
Generating mutation plots.
Highly correlated genes for RECQL5:
Showing top 20/1411 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RECQL5 | PADI1 | 0.791402 | 9 | 0 | 9 |
| RECQL5 | SCNN1B | 0.791296 | 10 | 0 | 10 |
| RECQL5 | MRPL38 | 0.788562 | 3 | 0 | 3 |
| RECQL5 | LLGL2 | 0.780324 | 11 | 0 | 11 |
| RECQL5 | COPE | 0.770056 | 3 | 0 | 3 |
| RECQL5 | RMND5B | 0.76046 | 12 | 0 | 12 |
| RECQL5 | MAB21L3 | 0.760241 | 5 | 0 | 5 |
| RECQL5 | EVPL | 0.758054 | 12 | 0 | 11 |
| RECQL5 | SMIM5 | 0.757752 | 7 | 0 | 7 |
| RECQL5 | PLEKHG6 | 0.755228 | 11 | 0 | 11 |
| RECQL5 | TOM1 | 0.754819 | 11 | 0 | 11 |
| RECQL5 | IDH3G | 0.754557 | 3 | 0 | 3 |
| RECQL5 | SNORA68 | 0.753297 | 4 | 0 | 4 |
| RECQL5 | ARHGAP27 | 0.751682 | 8 | 0 | 8 |
| RECQL5 | EPS8L1 | 0.750281 | 11 | 0 | 11 |
| RECQL5 | GTF3C1 | 0.749671 | 11 | 0 | 11 |
| RECQL5 | AP3M1 | 0.749492 | 3 | 0 | 3 |
| RECQL5 | TRIP10 | 0.746126 | 12 | 0 | 12 |
| RECQL5 | TPCN1 | 0.745889 | 11 | 0 | 10 |
| RECQL5 | SLC10A5 | 0.742658 | 3 | 0 | 3 |
For details and further investigation, click here
