| Full name: RAS like family 12 | Alias Symbol: RIS | ||
| Type: protein-coding gene | Cytoband: 15q22.31 | ||
| Entrez ID: 51285 | HGNC ID: HGNC:30289 | Ensembl Gene: ENSG00000103710 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of RASL12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RASL12 | 51285 | 219167_at | -1.1706 | 0.3584 | |
| GSE20347 | RASL12 | 51285 | 219167_at | -0.3651 | 0.1921 | |
| GSE23400 | RASL12 | 51285 | 219167_at | -0.7510 | 0.0000 | |
| GSE26886 | RASL12 | 51285 | 219167_at | 0.3650 | 0.0815 | |
| GSE29001 | RASL12 | 51285 | 219167_at | -0.2791 | 0.1865 | |
| GSE38129 | RASL12 | 51285 | 219167_at | -1.0145 | 0.0079 | |
| GSE45670 | RASL12 | 51285 | 219167_at | -1.6646 | 0.0000 | |
| GSE53622 | RASL12 | 51285 | 81228 | -1.3989 | 0.0000 | |
| GSE53624 | RASL12 | 51285 | 81228 | -1.3159 | 0.0000 | |
| GSE63941 | RASL12 | 51285 | 219167_at | -2.0059 | 0.0000 | |
| GSE77861 | RASL12 | 51285 | 219167_at | -0.0266 | 0.8650 | |
| GSE97050 | RASL12 | 51285 | A_24_P150580 | -0.9257 | 0.2410 | |
| SRP007169 | RASL12 | 51285 | RNAseq | 0.6058 | 0.3503 | |
| SRP064894 | RASL12 | 51285 | RNAseq | -0.1939 | 0.6394 | |
| SRP133303 | RASL12 | 51285 | RNAseq | -1.5140 | 0.0000 | |
| SRP159526 | RASL12 | 51285 | RNAseq | -0.9137 | 0.0152 | |
| SRP219564 | RASL12 | 51285 | RNAseq | -0.3152 | 0.7738 | |
| TCGA | RASL12 | 51285 | RNAseq | -0.5078 | 0.0059 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by RASL12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RASL12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RASL12 | 51285 | 7 | 3 | 20 | |
| GSE20123 | RASL12 | 51285 | 7 | 3 | 20 | |
| GSE43470 | RASL12 | 51285 | 4 | 6 | 33 | |
| GSE46452 | RASL12 | 51285 | 3 | 7 | 49 | |
| GSE47630 | RASL12 | 51285 | 8 | 10 | 22 | |
| GSE54993 | RASL12 | 51285 | 5 | 6 | 59 | |
| GSE54994 | RASL12 | 51285 | 6 | 7 | 40 | |
| GSE60625 | RASL12 | 51285 | 4 | 0 | 7 | |
| GSE74703 | RASL12 | 51285 | 4 | 3 | 29 | |
| GSE74704 | RASL12 | 51285 | 3 | 3 | 14 | |
| TCGA | RASL12 | 51285 | 10 | 16 | 70 |
Total number of gains: 61; Total number of losses: 64; Total Number of normals: 363.
Somatic mutations of RASL12:
Generating mutation plots.
Highly correlated genes for RASL12:
Showing top 20/1289 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RASL12 | FAM13C | 0.854765 | 4 | 0 | 4 |
| RASL12 | RBPMS2 | 0.853346 | 7 | 0 | 7 |
| RASL12 | ANGPTL1 | 0.817884 | 6 | 0 | 6 |
| RASL12 | ITGB1BP2 | 0.807841 | 5 | 0 | 5 |
| RASL12 | CLIP3 | 0.80615 | 11 | 0 | 11 |
| RASL12 | MRVI1 | 0.803071 | 7 | 0 | 7 |
| RASL12 | PLN | 0.798292 | 12 | 0 | 12 |
| RASL12 | SORCS1 | 0.797958 | 4 | 0 | 4 |
| RASL12 | XKR4 | 0.797626 | 5 | 0 | 5 |
| RASL12 | LMOD1 | 0.797458 | 12 | 0 | 12 |
| RASL12 | PPP1R12B | 0.796571 | 10 | 0 | 10 |
| RASL12 | PGR | 0.793762 | 5 | 0 | 4 |
| RASL12 | ASB5 | 0.793377 | 6 | 0 | 6 |
| RASL12 | ITGA7 | 0.793325 | 10 | 0 | 10 |
| RASL12 | JAM3 | 0.792967 | 12 | 0 | 12 |
| RASL12 | PRUNE2 | 0.791318 | 12 | 0 | 12 |
| RASL12 | PARD3B | 0.790688 | 5 | 0 | 5 |
| RASL12 | LRRN4CL | 0.789831 | 7 | 0 | 7 |
| RASL12 | PDZRN4 | 0.789237 | 11 | 0 | 11 |
| RASL12 | ATP1A2 | 0.787443 | 10 | 0 | 10 |
For details and further investigation, click here
