| Full name: LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated | Alias Symbol: YNL147W | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 51690 | HGNC ID: HGNC:20470 | Ensembl Gene: ENSG00000130332 | OMIM ID: 607287 |
| Drug and gene relationship at DGIdb | |||
Expression of LSM7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LSM7 | 51690 | 204559_s_at | 0.3945 | 0.1768 | |
| GSE20347 | LSM7 | 51690 | 204559_s_at | 0.5419 | 0.0009 | |
| GSE23400 | LSM7 | 51690 | 204559_s_at | 0.5741 | 0.0000 | |
| GSE26886 | LSM7 | 51690 | 204559_s_at | 1.8184 | 0.0000 | |
| GSE29001 | LSM7 | 51690 | 204559_s_at | 0.2108 | 0.7700 | |
| GSE38129 | LSM7 | 51690 | 204559_s_at | 0.7613 | 0.0000 | |
| GSE45670 | LSM7 | 51690 | 204559_s_at | 0.4318 | 0.0020 | |
| GSE53622 | LSM7 | 51690 | 49846 | 0.3851 | 0.0000 | |
| GSE53624 | LSM7 | 51690 | 49846 | 0.7141 | 0.0000 | |
| GSE63941 | LSM7 | 51690 | 204559_s_at | 0.8036 | 0.0030 | |
| GSE77861 | LSM7 | 51690 | 204559_s_at | 0.6324 | 0.0108 | |
| GSE97050 | LSM7 | 51690 | A_23_P90463 | 0.3865 | 0.2018 | |
| SRP007169 | LSM7 | 51690 | RNAseq | 0.7685 | 0.0864 | |
| SRP008496 | LSM7 | 51690 | RNAseq | 0.7482 | 0.0163 | |
| SRP064894 | LSM7 | 51690 | RNAseq | 0.8965 | 0.0116 | |
| SRP133303 | LSM7 | 51690 | RNAseq | 0.5699 | 0.0176 | |
| SRP159526 | LSM7 | 51690 | RNAseq | 0.3509 | 0.0238 | |
| SRP193095 | LSM7 | 51690 | RNAseq | -0.1225 | 0.3687 | |
| SRP219564 | LSM7 | 51690 | RNAseq | 0.6425 | 0.0296 | |
| TCGA | LSM7 | 51690 | RNAseq | 0.3726 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by LSM7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LSM7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LSM7 | 51690 | 4 | 4 | 22 | |
| GSE20123 | LSM7 | 51690 | 4 | 4 | 22 | |
| GSE43470 | LSM7 | 51690 | 1 | 10 | 32 | |
| GSE46452 | LSM7 | 51690 | 47 | 1 | 11 | |
| GSE47630 | LSM7 | 51690 | 5 | 7 | 28 | |
| GSE54993 | LSM7 | 51690 | 16 | 3 | 51 | |
| GSE54994 | LSM7 | 51690 | 8 | 15 | 30 | |
| GSE60625 | LSM7 | 51690 | 9 | 0 | 2 | |
| GSE74703 | LSM7 | 51690 | 1 | 7 | 28 | |
| GSE74704 | LSM7 | 51690 | 2 | 3 | 15 | |
| TCGA | LSM7 | 51690 | 6 | 25 | 65 |
Total number of gains: 103; Total number of losses: 79; Total Number of normals: 306.
Somatic mutations of LSM7:
Generating mutation plots.
Highly correlated genes for LSM7:
Showing top 20/1862 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LSM7 | COMMD7 | 0.826418 | 3 | 0 | 3 |
| LSM7 | ANKIB1 | 0.825976 | 3 | 0 | 3 |
| LSM7 | TMEM216 | 0.778468 | 4 | 0 | 4 |
| LSM7 | LSM4 | 0.772521 | 10 | 0 | 10 |
| LSM7 | SPNS1 | 0.770643 | 3 | 0 | 3 |
| LSM7 | THEM4 | 0.754 | 3 | 0 | 3 |
| LSM7 | PCGF6 | 0.752741 | 3 | 0 | 3 |
| LSM7 | CWF19L1 | 0.741759 | 5 | 0 | 5 |
| LSM7 | EFTUD2 | 0.734556 | 8 | 0 | 8 |
| LSM7 | LRRCC1 | 0.733727 | 3 | 0 | 3 |
| LSM7 | LRRC58 | 0.733523 | 5 | 0 | 5 |
| LSM7 | PXYLP1 | 0.732234 | 5 | 0 | 5 |
| LSM7 | ALKBH6 | 0.732098 | 4 | 0 | 4 |
| LSM7 | DNMT1 | 0.731708 | 11 | 0 | 10 |
| LSM7 | MCOLN1 | 0.731527 | 3 | 0 | 3 |
| LSM7 | SNRPA | 0.724735 | 11 | 0 | 11 |
| LSM7 | NACC1 | 0.722004 | 4 | 0 | 4 |
| LSM7 | BRCA1 | 0.722003 | 10 | 0 | 9 |
| LSM7 | IFT22 | 0.721729 | 3 | 0 | 3 |
| LSM7 | SNRPG | 0.716357 | 10 | 0 | 9 |
For details and further investigation, click here
