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Multi-Omics Database of ESCC

 

PCGF6

 

Full name: polycomb group ring finger 6 Alias Symbol: MBLR
Type: protein-coding gene Cytoband: 10q24.33
Entrez ID: 84108 HGNC ID: HGNC:21156 Ensembl Gene: ENSG00000156374 OMIM ID: 607816
Drug and gene relationship at DGIdb

 

Expression of PCGF6:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PCGF6 84108 224326_s_at 0.3467 0.4079
GSE26886 PCGF6 84108 224326_s_at 0.0711 0.7674
GSE45670 PCGF6 84108 224326_s_at 0.0538 0.8130
GSE53622 PCGF6 84108 71824 -0.1292 0.1271
GSE53624 PCGF6 84108 38640 0.1612 0.0678
GSE63941 PCGF6 84108 224326_s_at -0.5347 0.1773
GSE77861 PCGF6 84108 224326_s_at 0.2744 0.2880
GSE97050 PCGF6 84108 A_23_P115703 0.0375 0.9018
SRP007169 PCGF6 84108 RNAseq 0.4083 0.3520
SRP008496 PCGF6 84108 RNAseq 0.9033 0.0050
SRP064894 PCGF6 84108 RNAseq 0.4910 0.0113
SRP133303 PCGF6 84108 RNAseq 0.7777 0.0000
SRP159526 PCGF6 84108 RNAseq 0.4984 0.2056
SRP193095 PCGF6 84108 RNAseq 0.5730 0.0000
SRP219564 PCGF6 84108 RNAseq 0.3819 0.3985
TCGA PCGF6 84108 RNAseq 0.2211 0.0016

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by PCGF6 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of PCGF6:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PCGF6 84108 2 9 19
GSE20123 PCGF6 84108 2 8 20
GSE43470 PCGF6 84108 0 8 35
GSE46452 PCGF6 84108 0 11 48
GSE47630 PCGF6 84108 2 14 24
GSE54993 PCGF6 84108 8 0 62
GSE54994 PCGF6 84108 1 11 41
GSE60625 PCGF6 84108 0 0 11
GSE74703 PCGF6 84108 0 5 31
GSE74704 PCGF6 84108 1 4 15
TCGA PCGF6 84108 5 29 62

Total number of gains: 21; Total number of losses: 99; Total Number of normals: 368.  

 

Somatic mutations of PCGF6:

 

Generating mutation plots.

 

Highly correlated genes for PCGF6:

 

Showing top 20/552 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PCGF6PARL0.837924303
PCGF6B3GALNT20.816184303
PCGF6UBIAD10.799975303
PCGF6FBXO330.797908303
PCGF6TSEN150.788934303
PCGF6TMEM1350.778626303
PCGF6ZFP370.778083303
PCGF6ICK0.775501303
PCGF6TRA2B0.773905404
PCGF6VKORC1L10.773554303
PCGF6PCID20.772648303
PCGF6FAN10.771063404
PCGF6KLHL150.768791403
PCGF6C2orf760.755957303
PCGF6ANGEL20.754635303
PCGF6LSM70.752741303
PCGF6MRPL470.74896303
PCGF6CTBP20.740354303
PCGF6B4GALT20.739334303
PCGF6MASTL0.733847303

For details and further investigation, click here