| Full name: leucine rich adaptor protein 1 | Alias Symbol: FLJ25163|LRAP35a | ||
| Type: protein-coding gene | Cytoband: 1p34.1 | ||
| Entrez ID: 541468 | HGNC ID: HGNC:32327 | Ensembl Gene: ENSG00000171357 | OMIM ID: 616129 |
| Drug and gene relationship at DGIdb | |||
Expression of LURAP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LURAP1 | 541468 | 235214_at | -0.1292 | 0.7085 | |
| GSE26886 | LURAP1 | 541468 | 235214_at | 0.1735 | 0.2727 | |
| GSE45670 | LURAP1 | 541468 | 235214_at | -0.1366 | 0.1221 | |
| GSE53622 | LURAP1 | 541468 | 64381 | -1.0164 | 0.0000 | |
| GSE53624 | LURAP1 | 541468 | 64381 | -0.8347 | 0.0000 | |
| GSE63941 | LURAP1 | 541468 | 235214_at | -0.1822 | 0.3168 | |
| GSE77861 | LURAP1 | 541468 | 235214_at | -0.0576 | 0.5599 | |
| SRP064894 | LURAP1 | 541468 | RNAseq | -0.0280 | 0.9288 | |
| SRP133303 | LURAP1 | 541468 | RNAseq | -0.4338 | 0.0048 | |
| SRP159526 | LURAP1 | 541468 | RNAseq | -0.7358 | 0.0483 | |
| SRP193095 | LURAP1 | 541468 | RNAseq | -0.0728 | 0.6639 | |
| SRP219564 | LURAP1 | 541468 | RNAseq | -0.7026 | 0.1232 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by LURAP1 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of LURAP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LURAP1 | 541468 | 4 | 3 | 23 | |
| GSE20123 | LURAP1 | 541468 | 4 | 2 | 24 | |
| GSE43470 | LURAP1 | 541468 | 5 | 2 | 36 | |
| GSE46452 | LURAP1 | 541468 | 2 | 1 | 56 | |
| GSE47630 | LURAP1 | 541468 | 8 | 4 | 28 | |
| GSE54993 | LURAP1 | 541468 | 0 | 1 | 69 | |
| GSE54994 | LURAP1 | 541468 | 11 | 2 | 40 | |
| GSE60625 | LURAP1 | 541468 | 0 | 0 | 11 | |
| GSE74703 | LURAP1 | 541468 | 4 | 1 | 31 | |
| GSE74704 | LURAP1 | 541468 | 2 | 0 | 18 | |
| TCGA | LURAP1 | 541468 | 10 | 17 | 69 |
Total number of gains: 50; Total number of losses: 33; Total Number of normals: 405.
Somatic mutations of LURAP1:
Generating mutation plots.
Highly correlated genes for LURAP1:
Showing top 20/296 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LURAP1 | FAM131B | 0.689564 | 3 | 0 | 3 |
| LURAP1 | DMD | 0.666045 | 3 | 0 | 3 |
| LURAP1 | ITGA9 | 0.662911 | 4 | 0 | 4 |
| LURAP1 | RGS5 | 0.661349 | 3 | 0 | 3 |
| LURAP1 | PDK4 | 0.658272 | 3 | 0 | 3 |
| LURAP1 | MAOB | 0.652783 | 3 | 0 | 3 |
| LURAP1 | DNAJC12 | 0.646575 | 3 | 0 | 3 |
| LURAP1 | LIFR | 0.646345 | 3 | 0 | 3 |
| LURAP1 | SPRY2 | 0.645495 | 3 | 0 | 3 |
| LURAP1 | TAGLN | 0.644538 | 5 | 0 | 5 |
| LURAP1 | NFATC4 | 0.637813 | 4 | 0 | 4 |
| LURAP1 | AKAP12 | 0.636598 | 4 | 0 | 4 |
| LURAP1 | CSRP1 | 0.635017 | 3 | 0 | 3 |
| LURAP1 | LINC01111 | 0.630309 | 3 | 0 | 3 |
| LURAP1 | AOC3 | 0.630037 | 3 | 0 | 3 |
| LURAP1 | TULP1 | 0.627306 | 3 | 0 | 3 |
| LURAP1 | MYLK | 0.626843 | 4 | 0 | 4 |
| LURAP1 | SNTB1 | 0.625166 | 3 | 0 | 3 |
| LURAP1 | PURG | 0.623795 | 4 | 0 | 3 |
| LURAP1 | MIR100HG | 0.623744 | 4 | 0 | 3 |
For details and further investigation, click here
