| Full name: purine rich element binding protein G | Alias Symbol: PURG-A|PURG-B | ||
| Type: protein-coding gene | Cytoband: 8p12 | ||
| Entrez ID: 29942 | HGNC ID: HGNC:17930 | Ensembl Gene: ENSG00000172733 | OMIM ID: 618041 |
| Drug and gene relationship at DGIdb | |||
Expression of PURG:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PURG | 29942 | 235634_at | -0.0828 | 0.8229 | |
| GSE20347 | PURG | 29942 | 220860_at | -0.0129 | 0.8355 | |
| GSE23400 | PURG | 29942 | 220860_at | -0.0055 | 0.8447 | |
| GSE26886 | PURG | 29942 | 235634_at | -0.0116 | 0.9600 | |
| GSE29001 | PURG | 29942 | 220860_at | -0.0636 | 0.6190 | |
| GSE38129 | PURG | 29942 | 220860_at | -0.0380 | 0.3991 | |
| GSE45670 | PURG | 29942 | 235634_at | -0.2987 | 0.0215 | |
| GSE53622 | PURG | 29942 | 110602 | -0.9510 | 0.0000 | |
| GSE53624 | PURG | 29942 | 110602 | -0.4505 | 0.0004 | |
| GSE63941 | PURG | 29942 | 235634_at | -0.6560 | 0.0429 | |
| GSE77861 | PURG | 29942 | 235634_at | -0.1211 | 0.3746 | |
| GSE97050 | PURG | 29942 | A_23_P111919 | -0.1053 | 0.8018 | |
| SRP133303 | PURG | 29942 | RNAseq | -0.6324 | 0.0856 | |
| TCGA | PURG | 29942 | RNAseq | -0.5729 | 0.2197 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PURG expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PURG:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PURG | 29942 | 4 | 11 | 15 | |
| GSE20123 | PURG | 29942 | 4 | 11 | 15 | |
| GSE43470 | PURG | 29942 | 4 | 7 | 32 | |
| GSE46452 | PURG | 29942 | 13 | 13 | 33 | |
| GSE47630 | PURG | 29942 | 10 | 8 | 22 | |
| GSE54993 | PURG | 29942 | 2 | 15 | 53 | |
| GSE54994 | PURG | 29942 | 12 | 15 | 26 | |
| GSE60625 | PURG | 29942 | 3 | 0 | 8 | |
| GSE74703 | PURG | 29942 | 4 | 6 | 26 | |
| GSE74704 | PURG | 29942 | 3 | 7 | 10 | |
| TCGA | PURG | 29942 | 19 | 40 | 37 |
Total number of gains: 78; Total number of losses: 133; Total Number of normals: 277.
Somatic mutations of PURG:
Generating mutation plots.
Highly correlated genes for PURG:
Showing top 20/336 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PURG | ADAM15 | 0.673606 | 3 | 0 | 3 |
| PURG | DEFB118 | 0.644551 | 3 | 0 | 3 |
| PURG | CXCR5 | 0.644471 | 3 | 0 | 3 |
| PURG | RAMP2 | 0.632993 | 6 | 0 | 5 |
| PURG | STAC | 0.631278 | 4 | 0 | 3 |
| PURG | TSGA13 | 0.63066 | 3 | 0 | 3 |
| PURG | LURAP1 | 0.623795 | 4 | 0 | 3 |
| PURG | IFNA14 | 0.613458 | 4 | 0 | 3 |
| PURG | RAB4B | 0.61332 | 4 | 0 | 4 |
| PURG | EPHA6 | 0.611343 | 4 | 0 | 3 |
| PURG | DSCAML1 | 0.607834 | 3 | 0 | 3 |
| PURG | FZD4 | 0.602659 | 7 | 0 | 5 |
| PURG | GPSM3 | 0.59892 | 4 | 0 | 3 |
| PURG | SULT1C4 | 0.598759 | 4 | 0 | 3 |
| PURG | ECSCR | 0.596361 | 5 | 0 | 3 |
| PURG | CYGB | 0.593965 | 4 | 0 | 3 |
| PURG | ADH1A | 0.593768 | 3 | 0 | 3 |
| PURG | SCN4B | 0.591051 | 7 | 0 | 5 |
| PURG | NR6A1 | 0.587397 | 4 | 0 | 3 |
| PURG | RUNX1T1 | 0.586736 | 8 | 0 | 7 |
For details and further investigation, click here
