| Full name: leucine zipper protein 1 | Alias Symbol: LUZP | ||
| Type: protein-coding gene | Cytoband: 1p36.12 | ||
| Entrez ID: 7798 | HGNC ID: HGNC:14985 | Ensembl Gene: ENSG00000169641 | OMIM ID: 601422 |
| Drug and gene relationship at DGIdb | |||
Expression of LUZP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LUZP1 | 7798 | 1558173_a_at | 0.0503 | 0.9740 | |
| GSE20347 | LUZP1 | 7798 | 221831_at | -0.0136 | 0.8799 | |
| GSE23400 | LUZP1 | 7798 | 221832_s_at | -0.0160 | 0.7503 | |
| GSE26886 | LUZP1 | 7798 | 1558173_a_at | 0.4289 | 0.0463 | |
| GSE29001 | LUZP1 | 7798 | 221832_s_at | 0.0956 | 0.7470 | |
| GSE38129 | LUZP1 | 7798 | 221831_at | -0.0804 | 0.3615 | |
| GSE45670 | LUZP1 | 7798 | 225831_at | 0.3022 | 0.0824 | |
| GSE53622 | LUZP1 | 7798 | 72280 | 0.1516 | 0.0276 | |
| GSE53624 | LUZP1 | 7798 | 72280 | 0.3427 | 0.0000 | |
| GSE63941 | LUZP1 | 7798 | 225831_at | -1.3395 | 0.0197 | |
| GSE77861 | LUZP1 | 7798 | 221831_at | -0.0397 | 0.7475 | |
| GSE97050 | LUZP1 | 7798 | A_23_P407142 | 0.0961 | 0.6324 | |
| SRP007169 | LUZP1 | 7798 | RNAseq | 1.2568 | 0.0076 | |
| SRP008496 | LUZP1 | 7798 | RNAseq | 1.1158 | 0.0000 | |
| SRP064894 | LUZP1 | 7798 | RNAseq | 0.3527 | 0.1252 | |
| SRP133303 | LUZP1 | 7798 | RNAseq | 0.4936 | 0.0437 | |
| SRP159526 | LUZP1 | 7798 | RNAseq | -0.2218 | 0.3459 | |
| SRP193095 | LUZP1 | 7798 | RNAseq | 0.4085 | 0.0017 | |
| SRP219564 | LUZP1 | 7798 | RNAseq | -0.0829 | 0.8039 | |
| TCGA | LUZP1 | 7798 | RNAseq | 0.0409 | 0.4742 |
Upregulated datasets: 2; Downregulated datasets: 1.
Survival by LUZP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LUZP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LUZP1 | 7798 | 0 | 5 | 25 | |
| GSE20123 | LUZP1 | 7798 | 0 | 4 | 26 | |
| GSE43470 | LUZP1 | 7798 | 2 | 6 | 35 | |
| GSE46452 | LUZP1 | 7798 | 5 | 1 | 53 | |
| GSE47630 | LUZP1 | 7798 | 8 | 3 | 29 | |
| GSE54993 | LUZP1 | 7798 | 2 | 1 | 67 | |
| GSE54994 | LUZP1 | 7798 | 11 | 4 | 38 | |
| GSE60625 | LUZP1 | 7798 | 0 | 0 | 11 | |
| GSE74703 | LUZP1 | 7798 | 1 | 4 | 31 | |
| GSE74704 | LUZP1 | 7798 | 0 | 0 | 20 | |
| TCGA | LUZP1 | 7798 | 9 | 23 | 64 |
Total number of gains: 38; Total number of losses: 51; Total Number of normals: 399.
Somatic mutations of LUZP1:
Generating mutation plots.
Highly correlated genes for LUZP1:
Showing top 20/61 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LUZP1 | NID2 | 0.770065 | 3 | 0 | 3 |
| LUZP1 | CEP104 | 0.765872 | 3 | 0 | 3 |
| LUZP1 | ARVCF | 0.748781 | 3 | 0 | 3 |
| LUZP1 | RALGDS | 0.722705 | 3 | 0 | 3 |
| LUZP1 | EVX1 | 0.722269 | 3 | 0 | 3 |
| LUZP1 | GRK4 | 0.702078 | 4 | 0 | 3 |
| LUZP1 | NRG4 | 0.700563 | 3 | 0 | 3 |
| LUZP1 | WDPCP | 0.686031 | 3 | 0 | 3 |
| LUZP1 | RIMS3 | 0.685315 | 3 | 0 | 3 |
| LUZP1 | DAB1 | 0.681853 | 3 | 0 | 3 |
| LUZP1 | P4HA3 | 0.669422 | 4 | 0 | 3 |
| LUZP1 | ZDHHC8 | 0.66844 | 4 | 0 | 3 |
| LUZP1 | COQ6 | 0.667426 | 4 | 0 | 3 |
| LUZP1 | SHROOM1 | 0.664141 | 4 | 0 | 3 |
| LUZP1 | NXF3 | 0.646246 | 3 | 0 | 3 |
| LUZP1 | RASL11B | 0.636251 | 3 | 0 | 3 |
| LUZP1 | PARP10 | 0.626914 | 4 | 0 | 3 |
| LUZP1 | TMA7 | 0.615182 | 4 | 0 | 3 |
| LUZP1 | CHSY3 | 0.609753 | 6 | 0 | 5 |
| LUZP1 | C22orf23 | 0.608925 | 4 | 0 | 3 |
For details and further investigation, click here
