| Full name: coenzyme Q6, monooxygenase | Alias Symbol: CGI-10 | ||
| Type: protein-coding gene | Cytoband: 14q24.3 | ||
| Entrez ID: 51004 | HGNC ID: HGNC:20233 | Ensembl Gene: ENSG00000119723 | OMIM ID: 614647 |
| Drug and gene relationship at DGIdb | |||
Expression of COQ6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COQ6 | 51004 | 218760_at | 0.0225 | 0.9494 | |
| GSE20347 | COQ6 | 51004 | 218760_at | -0.0824 | 0.4152 | |
| GSE23400 | COQ6 | 51004 | 218760_at | -0.0461 | 0.3409 | |
| GSE26886 | COQ6 | 51004 | 218760_at | -0.1021 | 0.4393 | |
| GSE29001 | COQ6 | 51004 | 218760_at | -0.1909 | 0.2254 | |
| GSE38129 | COQ6 | 51004 | 218760_at | -0.1620 | 0.0587 | |
| GSE45670 | COQ6 | 51004 | 218760_at | -0.1382 | 0.2312 | |
| GSE53622 | COQ6 | 51004 | 22071 | 0.1500 | 0.0518 | |
| GSE53624 | COQ6 | 51004 | 22071 | 0.0372 | 0.6684 | |
| GSE63941 | COQ6 | 51004 | 218760_at | -0.0096 | 0.9841 | |
| GSE77861 | COQ6 | 51004 | 218760_at | 0.0400 | 0.8295 | |
| GSE97050 | COQ6 | 51004 | A_23_P65584 | 0.2334 | 0.3238 | |
| SRP007169 | COQ6 | 51004 | RNAseq | -0.5687 | 0.2013 | |
| SRP008496 | COQ6 | 51004 | RNAseq | -0.3718 | 0.2623 | |
| SRP064894 | COQ6 | 51004 | RNAseq | 0.2900 | 0.1110 | |
| SRP133303 | COQ6 | 51004 | RNAseq | 0.0440 | 0.7840 | |
| SRP159526 | COQ6 | 51004 | RNAseq | 0.1285 | 0.5768 | |
| SRP193095 | COQ6 | 51004 | RNAseq | -0.1117 | 0.3028 | |
| SRP219564 | COQ6 | 51004 | RNAseq | -0.1416 | 0.6628 | |
| TCGA | COQ6 | 51004 | RNAseq | -0.1464 | 0.0127 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by COQ6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COQ6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COQ6 | 51004 | 8 | 2 | 20 | |
| GSE20123 | COQ6 | 51004 | 8 | 2 | 20 | |
| GSE43470 | COQ6 | 51004 | 8 | 3 | 32 | |
| GSE46452 | COQ6 | 51004 | 16 | 3 | 40 | |
| GSE47630 | COQ6 | 51004 | 11 | 8 | 21 | |
| GSE54993 | COQ6 | 51004 | 3 | 8 | 59 | |
| GSE54994 | COQ6 | 51004 | 19 | 4 | 30 | |
| GSE60625 | COQ6 | 51004 | 0 | 2 | 9 | |
| GSE74703 | COQ6 | 51004 | 7 | 3 | 26 | |
| GSE74704 | COQ6 | 51004 | 3 | 2 | 15 | |
| TCGA | COQ6 | 51004 | 32 | 16 | 48 |
Total number of gains: 115; Total number of losses: 53; Total Number of normals: 320.
Somatic mutations of COQ6:
Generating mutation plots.
Highly correlated genes for COQ6:
Showing top 20/31 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COQ6 | EGR4 | 0.679994 | 3 | 0 | 3 |
| COQ6 | LUZP1 | 0.667426 | 4 | 0 | 3 |
| COQ6 | PEX11G | 0.629951 | 4 | 0 | 3 |
| COQ6 | POC1A | 0.619519 | 4 | 0 | 3 |
| COQ6 | TTLL5 | 0.606723 | 4 | 0 | 3 |
| COQ6 | SHARPIN | 0.59963 | 4 | 0 | 3 |
| COQ6 | TCEAL7 | 0.595537 | 3 | 0 | 3 |
| COQ6 | SUPT3H | 0.590343 | 3 | 0 | 3 |
| COQ6 | PPP1R13B | 0.582616 | 5 | 0 | 3 |
| COQ6 | PICK1 | 0.577605 | 4 | 0 | 3 |
| COQ6 | INF2 | 0.577005 | 4 | 0 | 3 |
| COQ6 | PHAX | 0.576086 | 4 | 0 | 3 |
| COQ6 | CDC42BPB | 0.573461 | 6 | 0 | 3 |
| COQ6 | NOX5 | 0.567155 | 4 | 0 | 3 |
| COQ6 | CYP39A1 | 0.567114 | 6 | 0 | 4 |
| COQ6 | POMT2 | 0.566198 | 5 | 0 | 3 |
| COQ6 | ACTR10 | 0.561725 | 7 | 0 | 5 |
| COQ6 | IFT43 | 0.558266 | 6 | 0 | 5 |
| COQ6 | GPATCH3 | 0.555526 | 4 | 0 | 3 |
| COQ6 | UQCRC1 | 0.542918 | 6 | 0 | 4 |
For details and further investigation, click here
