| Full name: suprabasin | Alias Symbol: UNQ698|HLAR698 | ||
| Type: protein-coding gene | Cytoband: 19q13.13 | ||
| Entrez ID: 374897 | HGNC ID: HGNC:24950 | Ensembl Gene: ENSG00000189001 | OMIM ID: 609969 |
| Drug and gene relationship at DGIdb | |||
Expression of SBSN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SBSN | 374897 | 235272_at | -2.6791 | 0.1876 | |
| GSE26886 | SBSN | 374897 | 235272_at | -5.1695 | 0.0000 | |
| GSE45670 | SBSN | 374897 | 235272_at | -0.0617 | 0.9057 | |
| GSE53622 | SBSN | 374897 | 55394 | -1.9099 | 0.0000 | |
| GSE53624 | SBSN | 374897 | 55394 | -2.5922 | 0.0000 | |
| GSE63941 | SBSN | 374897 | 235272_at | -0.3727 | 0.2313 | |
| GSE77861 | SBSN | 374897 | 235272_at | -1.5872 | 0.0096 | |
| GSE97050 | SBSN | 374897 | A_33_P3269636 | -0.2257 | 0.6965 | |
| SRP007169 | SBSN | 374897 | RNAseq | -5.4526 | 0.0000 | |
| SRP008496 | SBSN | 374897 | RNAseq | -4.6805 | 0.0000 | |
| SRP064894 | SBSN | 374897 | RNAseq | -2.4775 | 0.0001 | |
| SRP133303 | SBSN | 374897 | RNAseq | -3.5000 | 0.0000 | |
| SRP159526 | SBSN | 374897 | RNAseq | -3.9549 | 0.0000 | |
| SRP219564 | SBSN | 374897 | RNAseq | -3.8773 | 0.0061 | |
| TCGA | SBSN | 374897 | RNAseq | 0.9121 | 0.0175 |
Upregulated datasets: 0; Downregulated datasets: 10.
Survival by SBSN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SBSN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SBSN | 374897 | 6 | 4 | 20 | |
| GSE20123 | SBSN | 374897 | 6 | 3 | 21 | |
| GSE43470 | SBSN | 374897 | 3 | 7 | 33 | |
| GSE46452 | SBSN | 374897 | 48 | 1 | 10 | |
| GSE47630 | SBSN | 374897 | 9 | 5 | 26 | |
| GSE54993 | SBSN | 374897 | 17 | 3 | 50 | |
| GSE54994 | SBSN | 374897 | 8 | 9 | 36 | |
| GSE60625 | SBSN | 374897 | 9 | 0 | 2 | |
| GSE74703 | SBSN | 374897 | 3 | 4 | 29 | |
| GSE74704 | SBSN | 374897 | 6 | 1 | 13 | |
| TCGA | SBSN | 374897 | 21 | 11 | 64 |
Total number of gains: 136; Total number of losses: 48; Total Number of normals: 304.
Somatic mutations of SBSN:
Generating mutation plots.
Highly correlated genes for SBSN:
Showing top 20/905 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SBSN | CNFN | 0.876837 | 8 | 0 | 8 |
| SBSN | SPRR2F | 0.871689 | 4 | 0 | 4 |
| SBSN | SPRR2E | 0.868835 | 4 | 0 | 4 |
| SBSN | SPRR2D | 0.866456 | 4 | 0 | 4 |
| SBSN | SPRR2A | 0.858686 | 4 | 0 | 4 |
| SBSN | SULT2B1 | 0.858472 | 6 | 0 | 6 |
| SBSN | TGM1 | 0.85566 | 8 | 0 | 8 |
| SBSN | NCCRP1 | 0.85004 | 4 | 0 | 4 |
| SBSN | CXCR2 | 0.833941 | 5 | 0 | 5 |
| SBSN | VSIG10L | 0.833712 | 7 | 0 | 7 |
| SBSN | CYSRT1 | 0.829291 | 6 | 0 | 6 |
| SBSN | LYPD3 | 0.819682 | 8 | 0 | 8 |
| SBSN | S100A9 | 0.813865 | 8 | 0 | 8 |
| SBSN | CRCT1 | 0.808696 | 9 | 0 | 8 |
| SBSN | KLK13 | 0.808611 | 8 | 0 | 8 |
| SBSN | CDA | 0.807395 | 7 | 0 | 7 |
| SBSN | TMEM79 | 0.803793 | 8 | 0 | 8 |
| SBSN | RNF222 | 0.798539 | 3 | 0 | 3 |
| SBSN | LYNX1 | 0.798237 | 8 | 0 | 8 |
| SBSN | TMPRSS11E | 0.79805 | 7 | 0 | 7 |
For details and further investigation, click here
