| Full name: zinc finger protein 750 | Alias Symbol: FLJ13841|Zfp750 | ||
| Type: protein-coding gene | Cytoband: 17q25.3 | ||
| Entrez ID: 79755 | HGNC ID: HGNC:25843 | Ensembl Gene: ENSG00000141579 | OMIM ID: 610226 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of ZNF750:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF750 | 79755 | 219995_s_at | -0.9348 | 0.3433 | |
| GSE20347 | ZNF750 | 79755 | 219995_s_at | -2.4458 | 0.0000 | |
| GSE23400 | ZNF750 | 79755 | 219995_s_at | -1.8120 | 0.0000 | |
| GSE26886 | ZNF750 | 79755 | 219995_s_at | -2.2142 | 0.0001 | |
| GSE29001 | ZNF750 | 79755 | 219995_s_at | -2.2815 | 0.0040 | |
| GSE38129 | ZNF750 | 79755 | 219995_s_at | -1.0176 | 0.2260 | |
| GSE45670 | ZNF750 | 79755 | 219995_s_at | -0.5832 | 0.0303 | |
| GSE53622 | ZNF750 | 79755 | 36612 | -1.6918 | 0.0000 | |
| GSE53624 | ZNF750 | 79755 | 36612 | -2.2427 | 0.0000 | |
| GSE63941 | ZNF750 | 79755 | 219995_s_at | 2.3388 | 0.0758 | |
| GSE77861 | ZNF750 | 79755 | 219995_s_at | -1.5668 | 0.1044 | |
| GSE97050 | ZNF750 | 79755 | A_33_P3423420 | -0.3530 | 0.5998 | |
| SRP007169 | ZNF750 | 79755 | RNAseq | -1.4789 | 0.0002 | |
| SRP008496 | ZNF750 | 79755 | RNAseq | -1.7036 | 0.0000 | |
| SRP064894 | ZNF750 | 79755 | RNAseq | -1.8790 | 0.0002 | |
| SRP133303 | ZNF750 | 79755 | RNAseq | -1.6884 | 0.0000 | |
| SRP159526 | ZNF750 | 79755 | RNAseq | -2.5447 | 0.0020 | |
| SRP193095 | ZNF750 | 79755 | RNAseq | -1.6006 | 0.0002 | |
| SRP219564 | ZNF750 | 79755 | RNAseq | -2.9572 | 0.0076 | |
| TCGA | ZNF750 | 79755 | RNAseq | 1.2154 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 13.
Survival by ZNF750 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF750:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF750 | 79755 | 4 | 5 | 21 | |
| GSE20123 | ZNF750 | 79755 | 4 | 5 | 21 | |
| GSE43470 | ZNF750 | 79755 | 3 | 5 | 35 | |
| GSE46452 | ZNF750 | 79755 | 34 | 0 | 25 | |
| GSE47630 | ZNF750 | 79755 | 9 | 2 | 29 | |
| GSE54993 | ZNF750 | 79755 | 2 | 5 | 63 | |
| GSE54994 | ZNF750 | 79755 | 10 | 6 | 37 | |
| GSE60625 | ZNF750 | 79755 | 6 | 0 | 5 | |
| GSE74703 | ZNF750 | 79755 | 3 | 3 | 30 | |
| GSE74704 | ZNF750 | 79755 | 4 | 4 | 12 | |
| TCGA | ZNF750 | 79755 | 23 | 16 | 57 |
Total number of gains: 102; Total number of losses: 51; Total Number of normals: 335.
Somatic mutations of ZNF750:
Generating mutation plots.
Highly correlated genes for ZNF750:
Showing top 20/1304 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF750 | PGLYRP3 | 0.890226 | 3 | 0 | 3 |
| ZNF750 | GRHL3 | 0.826565 | 9 | 0 | 8 |
| ZNF750 | TMPRSS11E | 0.822055 | 10 | 0 | 10 |
| ZNF750 | KRT83 | 0.816662 | 3 | 0 | 3 |
| ZNF750 | CSTB | 0.802525 | 12 | 0 | 12 |
| ZNF750 | LYPD3 | 0.799953 | 12 | 0 | 11 |
| ZNF750 | S100A16 | 0.797193 | 8 | 0 | 8 |
| ZNF750 | ZNF185 | 0.788325 | 12 | 0 | 11 |
| ZNF750 | CYSRT1 | 0.786052 | 6 | 0 | 5 |
| ZNF750 | RHCG | 0.785014 | 11 | 0 | 10 |
| ZNF750 | TGM1 | 0.7815 | 12 | 0 | 11 |
| ZNF750 | SPRR2F | 0.779747 | 4 | 0 | 4 |
| ZNF750 | ARHGAP32 | 0.779481 | 11 | 0 | 11 |
| ZNF750 | PITX1 | 0.779127 | 12 | 0 | 11 |
| ZNF750 | SPRR2A | 0.778765 | 4 | 0 | 4 |
| ZNF750 | APOBEC1 | 0.773723 | 3 | 0 | 3 |
| ZNF750 | FUT3 | 0.772997 | 12 | 0 | 11 |
| ZNF750 | RAB25 | 0.769503 | 13 | 0 | 13 |
| ZNF750 | SPRR2D | 0.769497 | 4 | 0 | 3 |
| ZNF750 | NIPAL1 | 0.768927 | 3 | 0 | 3 |
For details and further investigation, click here
