ANXA1

 

Full name: annexin A1 Alias Symbol: 
Type: protein-coding gene Cytoband: 9q21.13
Entrez ID: 301 HGNC ID: HGNC:533 Ensembl Gene: ENSG00000135046 OMIM ID: 151690
Drug and gene relationship at DGIdb

 

Expression of ANXA1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ANXA1 301 201012_at -0.9378 0.2772
GSE20347 ANXA1 301 201012_at -1.4977 0.0000
GSE23400 ANXA1 301 201012_at -1.4714 0.0000
GSE26886 ANXA1 301 201012_at -2.8758 0.0000
GSE29001 ANXA1 301 201012_at -2.1099 0.0008
GSE38129 ANXA1 301 201012_at -1.1387 0.0026
GSE45670 ANXA1 301 201012_at -0.3118 0.0455
GSE53622 ANXA1 301 137700 -2.0956 0.0000
GSE53624 ANXA1 301 137700 -2.7377 0.0000
GSE63941 ANXA1 301 201012_at -0.8970 0.3462
GSE77861 ANXA1 301 201012_at -0.5850 0.0296
GSE97050 ANXA1 301 A_23_P94501 -0.8269 0.4573
SRP007169 ANXA1 301 RNAseq -4.2053 0.0000
SRP008496 ANXA1 301 RNAseq -4.5380 0.0000
SRP064894 ANXA1 301 RNAseq -3.3112 0.0000
SRP133303 ANXA1 301 RNAseq -3.3226 0.0000
SRP159526 ANXA1 301 RNAseq -4.6076 0.0000
SRP193095 ANXA1 301 RNAseq -3.4614 0.0000
SRP219564 ANXA1 301 RNAseq -3.7846 0.0000
TCGA ANXA1 301 RNAseq 0.2825 0.0175

Upregulated datasets: 0; Downregulated datasets: 14.  

 

Survival by ANXA1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of ANXA1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ANXA1 301 6 10 14
GSE20123 ANXA1 301 6 10 14
GSE43470 ANXA1 301 6 5 32
GSE46452 ANXA1 301 6 14 39
GSE47630 ANXA1 301 1 18 21
GSE54993 ANXA1 301 4 1 65
GSE54994 ANXA1 301 4 13 36
GSE60625 ANXA1 301 0 0 11
GSE74703 ANXA1 301 5 4 27
GSE74704 ANXA1 301 3 8 9
TCGA ANXA1 301 19 27 50

Total number of gains: 60; Total number of losses: 110; Total Number of normals: 318.  

 

Somatic mutations of ANXA1:

 

Generating mutation plots.

 

Highly correlated genes for ANXA1:

 

Showing top 20/1301 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ANXA1CYSRT10.904107606
ANXA1MALL0.87975812012
ANXA1CSTB0.87345712012
ANXA1SCEL0.86251112012
ANXA1SERPINB10.85374712012
ANXA1TMPRSS11E0.85314111011
ANXA1EMP10.84912612011
ANXA1RAB11A0.8469110010
ANXA1SERPINB20.84658812012
ANXA1TMEM1540.840571808
ANXA1C5orf66-AS10.836177606
ANXA1ECM10.83525212012
ANXA1S100A140.82917812011
ANXA1SPINK50.82846412011
ANXA1IL180.82797111011
ANXA1TGM10.82733312012
ANXA1ZNF1850.82555712012
ANXA1S100A160.821325807
ANXA1A2ML10.820422808
ANXA1PRSS270.818524808

For details and further investigation, click here