| Full name: mal, T cell differentiation protein like | Alias Symbol: BENE | ||
| Type: protein-coding gene | Cytoband: 2q13 | ||
| Entrez ID: 7851 | HGNC ID: HGNC:6818 | Ensembl Gene: ENSG00000144063 | OMIM ID: 602022 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MALL:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MALL | 7851 | 209373_at | -1.7501 | 0.1943 | |
| GSE20347 | MALL | 7851 | 209373_at | -3.0410 | 0.0000 | |
| GSE23400 | MALL | 7851 | 209373_at | -2.2316 | 0.0000 | |
| GSE26886 | MALL | 7851 | 209373_at | -4.0692 | 0.0000 | |
| GSE29001 | MALL | 7851 | 209373_at | -3.0357 | 0.0000 | |
| GSE38129 | MALL | 7851 | 209373_at | -2.1587 | 0.0001 | |
| GSE45670 | MALL | 7851 | 209373_at | -0.9445 | 0.0053 | |
| GSE53622 | MALL | 7851 | 41243 | -2.3403 | 0.0000 | |
| GSE53624 | MALL | 7851 | 41243 | -2.5537 | 0.0000 | |
| GSE63941 | MALL | 7851 | 209373_at | 1.0881 | 0.4463 | |
| GSE77861 | MALL | 7851 | 209373_at | -1.6401 | 0.0182 | |
| GSE97050 | MALL | 7851 | A_24_P80204 | -0.4309 | 0.7335 | |
| SRP007169 | MALL | 7851 | RNAseq | -3.8550 | 0.0000 | |
| SRP008496 | MALL | 7851 | RNAseq | -3.9438 | 0.0000 | |
| SRP064894 | MALL | 7851 | RNAseq | -3.5932 | 0.0000 | |
| SRP133303 | MALL | 7851 | RNAseq | -2.7163 | 0.0000 | |
| SRP159526 | MALL | 7851 | RNAseq | -3.8201 | 0.0000 | |
| SRP193095 | MALL | 7851 | RNAseq | -2.8093 | 0.0000 | |
| SRP219564 | MALL | 7851 | RNAseq | -3.2597 | 0.0000 | |
| TCGA | MALL | 7851 | RNAseq | 0.2900 | 0.0679 |
Upregulated datasets: 0; Downregulated datasets: 15.
Survival by MALL expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MALL:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MALL | 7851 | 4 | 2 | 24 | |
| GSE20123 | MALL | 7851 | 4 | 2 | 24 | |
| GSE43470 | MALL | 7851 | 3 | 1 | 39 | |
| GSE46452 | MALL | 7851 | 1 | 4 | 54 | |
| GSE47630 | MALL | 7851 | 7 | 0 | 33 | |
| GSE54993 | MALL | 7851 | 0 | 6 | 64 | |
| GSE54994 | MALL | 7851 | 10 | 0 | 43 | |
| GSE60625 | MALL | 7851 | 0 | 3 | 8 | |
| GSE74703 | MALL | 7851 | 3 | 1 | 32 | |
| GSE74704 | MALL | 7851 | 2 | 2 | 16 | |
| TCGA | MALL | 7851 | 32 | 5 | 59 |
Total number of gains: 66; Total number of losses: 26; Total Number of normals: 396.
Somatic mutations of MALL:
Generating mutation plots.
Highly correlated genes for MALL:
Showing top 20/1382 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MALL | PPL | 0.881241 | 12 | 0 | 12 |
| MALL | ANXA1 | 0.879758 | 12 | 0 | 12 |
| MALL | EVPL | 0.876529 | 12 | 0 | 12 |
| MALL | C1orf116 | 0.869778 | 12 | 0 | 12 |
| MALL | CSTB | 0.865569 | 12 | 0 | 12 |
| MALL | APOBEC1 | 0.859604 | 3 | 0 | 3 |
| MALL | SCEL | 0.858533 | 13 | 0 | 13 |
| MALL | VSIG10L | 0.858479 | 7 | 0 | 7 |
| MALL | ECM1 | 0.857648 | 12 | 0 | 12 |
| MALL | CRCT1 | 0.851353 | 12 | 0 | 12 |
| MALL | CNFN | 0.850947 | 8 | 0 | 8 |
| MALL | GRHL3 | 0.850627 | 8 | 0 | 8 |
| MALL | MGLL | 0.847174 | 10 | 0 | 10 |
| MALL | CLIC3 | 0.846548 | 10 | 0 | 10 |
| MALL | CYSRT1 | 0.842041 | 7 | 0 | 6 |
| MALL | IL18 | 0.841564 | 11 | 0 | 11 |
| MALL | TRIP10 | 0.840125 | 11 | 0 | 11 |
| MALL | IL1RN | 0.838609 | 13 | 0 | 12 |
| MALL | TMPRSS11E | 0.837443 | 12 | 0 | 12 |
| MALL | SULT2B1 | 0.836553 | 10 | 0 | 10 |
For details and further investigation, click here
