| Full name: LysM domain containing 2 | Alias Symbol: MGC35274 | ||
| Type: protein-coding gene | Cytoband: 15q21.2 | ||
| Entrez ID: 256586 | HGNC ID: HGNC:28571 | Ensembl Gene: ENSG00000140280 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of LYSMD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LYSMD2 | 256586 | 226748_at | -0.1060 | 0.8628 | |
| GSE26886 | LYSMD2 | 256586 | 226748_at | 0.7934 | 0.0045 | |
| GSE45670 | LYSMD2 | 256586 | 226748_at | 0.0356 | 0.8898 | |
| GSE53622 | LYSMD2 | 256586 | 17517 | 0.0461 | 0.6256 | |
| GSE53624 | LYSMD2 | 256586 | 17517 | 0.1521 | 0.1669 | |
| GSE63941 | LYSMD2 | 256586 | 226748_at | 0.6447 | 0.2281 | |
| GSE77861 | LYSMD2 | 256586 | 226748_at | 0.1795 | 0.4250 | |
| GSE97050 | LYSMD2 | 256586 | A_32_P120895 | -0.0577 | 0.8236 | |
| SRP007169 | LYSMD2 | 256586 | RNAseq | 0.2539 | 0.6348 | |
| SRP008496 | LYSMD2 | 256586 | RNAseq | 0.4166 | 0.2508 | |
| SRP064894 | LYSMD2 | 256586 | RNAseq | 0.2219 | 0.1550 | |
| SRP133303 | LYSMD2 | 256586 | RNAseq | 0.3321 | 0.0622 | |
| SRP159526 | LYSMD2 | 256586 | RNAseq | -0.2587 | 0.6486 | |
| SRP193095 | LYSMD2 | 256586 | RNAseq | 0.1810 | 0.1643 | |
| SRP219564 | LYSMD2 | 256586 | RNAseq | 0.2525 | 0.3987 | |
| TCGA | LYSMD2 | 256586 | RNAseq | 0.1484 | 0.0828 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LYSMD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LYSMD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LYSMD2 | 256586 | 6 | 4 | 20 | |
| GSE20123 | LYSMD2 | 256586 | 6 | 4 | 20 | |
| GSE43470 | LYSMD2 | 256586 | 4 | 3 | 36 | |
| GSE46452 | LYSMD2 | 256586 | 3 | 7 | 49 | |
| GSE47630 | LYSMD2 | 256586 | 8 | 10 | 22 | |
| GSE54993 | LYSMD2 | 256586 | 4 | 6 | 60 | |
| GSE54994 | LYSMD2 | 256586 | 5 | 7 | 41 | |
| GSE60625 | LYSMD2 | 256586 | 4 | 0 | 7 | |
| GSE74703 | LYSMD2 | 256586 | 4 | 2 | 30 | |
| GSE74704 | LYSMD2 | 256586 | 2 | 3 | 15 | |
| TCGA | LYSMD2 | 256586 | 9 | 17 | 70 |
Total number of gains: 55; Total number of losses: 63; Total Number of normals: 370.
Somatic mutations of LYSMD2:
Generating mutation plots.
Highly correlated genes for LYSMD2:
Showing top 20/297 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LYSMD2 | ELOVL7 | 0.747594 | 3 | 0 | 3 |
| LYSMD2 | RARS2 | 0.742296 | 3 | 0 | 3 |
| LYSMD2 | ASCC3 | 0.741979 | 3 | 0 | 3 |
| LYSMD2 | VMA21 | 0.741834 | 3 | 0 | 3 |
| LYSMD2 | DHRSX | 0.738852 | 3 | 0 | 3 |
| LYSMD2 | AKIP1 | 0.720074 | 3 | 0 | 3 |
| LYSMD2 | TTC8 | 0.707866 | 3 | 0 | 3 |
| LYSMD2 | PIGF | 0.705641 | 3 | 0 | 3 |
| LYSMD2 | SCAMP1 | 0.70409 | 4 | 0 | 4 |
| LYSMD2 | SACS | 0.700436 | 3 | 0 | 3 |
| LYSMD2 | DCTN4 | 0.700199 | 3 | 0 | 3 |
| LYSMD2 | DCTD | 0.69687 | 3 | 0 | 3 |
| LYSMD2 | RPA1 | 0.696552 | 3 | 0 | 3 |
| LYSMD2 | ALS2 | 0.69515 | 3 | 0 | 3 |
| LYSMD2 | ETS2 | 0.692146 | 3 | 0 | 3 |
| LYSMD2 | NDUFS2 | 0.687243 | 3 | 0 | 3 |
| LYSMD2 | RAPGEF6 | 0.684646 | 4 | 0 | 3 |
| LYSMD2 | TBC1D2 | 0.684094 | 3 | 0 | 3 |
| LYSMD2 | CDNF | 0.682045 | 3 | 0 | 3 |
| LYSMD2 | PTPRE | 0.67841 | 3 | 0 | 3 |
For details and further investigation, click here
