| Full name: protein tyrosine phosphatase receptor type E | Alias Symbol: PTPE | ||
| Type: protein-coding gene | Cytoband: 10q26.2 | ||
| Entrez ID: 5791 | HGNC ID: HGNC:9669 | Ensembl Gene: ENSG00000132334 | OMIM ID: 600926 |
| Drug and gene relationship at DGIdb | |||
Expression of PTPRE:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PTPRE | 5791 | 221840_at | 0.4351 | 0.6700 | |
| GSE20347 | PTPRE | 5791 | 221840_at | -0.3252 | 0.0309 | |
| GSE23400 | PTPRE | 5791 | 221840_at | 0.1621 | 0.0760 | |
| GSE26886 | PTPRE | 5791 | 221840_at | -0.2116 | 0.2392 | |
| GSE29001 | PTPRE | 5791 | 221840_at | -0.0608 | 0.8760 | |
| GSE38129 | PTPRE | 5791 | 221840_at | -0.0406 | 0.8037 | |
| GSE45670 | PTPRE | 5791 | 221840_at | 0.1822 | 0.3950 | |
| GSE53622 | PTPRE | 5791 | 39919 | -0.1843 | 0.1053 | |
| GSE53624 | PTPRE | 5791 | 39919 | 0.1024 | 0.3128 | |
| GSE63941 | PTPRE | 5791 | 221840_at | -0.0457 | 0.9679 | |
| GSE77861 | PTPRE | 5791 | 221840_at | 0.1262 | 0.7880 | |
| GSE97050 | PTPRE | 5791 | A_33_P3309556 | 0.4917 | 0.2151 | |
| SRP007169 | PTPRE | 5791 | RNAseq | 0.7997 | 0.0747 | |
| SRP008496 | PTPRE | 5791 | RNAseq | 0.8547 | 0.0078 | |
| SRP064894 | PTPRE | 5791 | RNAseq | 0.2603 | 0.3807 | |
| SRP133303 | PTPRE | 5791 | RNAseq | 0.2526 | 0.0983 | |
| SRP159526 | PTPRE | 5791 | RNAseq | -0.3113 | 0.4078 | |
| SRP193095 | PTPRE | 5791 | RNAseq | 0.8536 | 0.0000 | |
| SRP219564 | PTPRE | 5791 | RNAseq | -0.0340 | 0.9346 | |
| TCGA | PTPRE | 5791 | RNAseq | 0.1317 | 0.0919 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PTPRE expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PTPRE:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PTPRE | 5791 | 2 | 7 | 21 | |
| GSE20123 | PTPRE | 5791 | 2 | 7 | 21 | |
| GSE43470 | PTPRE | 5791 | 0 | 10 | 33 | |
| GSE46452 | PTPRE | 5791 | 0 | 11 | 48 | |
| GSE47630 | PTPRE | 5791 | 4 | 13 | 23 | |
| GSE54993 | PTPRE | 5791 | 8 | 1 | 61 | |
| GSE54994 | PTPRE | 5791 | 1 | 9 | 43 | |
| GSE60625 | PTPRE | 5791 | 0 | 0 | 11 | |
| GSE74703 | PTPRE | 5791 | 0 | 6 | 30 | |
| GSE74704 | PTPRE | 5791 | 2 | 3 | 15 | |
| TCGA | PTPRE | 5791 | 7 | 27 | 62 |
Total number of gains: 26; Total number of losses: 94; Total Number of normals: 368.
Somatic mutations of PTPRE:
Generating mutation plots.
Highly correlated genes for PTPRE:
Showing top 20/94 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PTPRE | RASGRP3 | 0.751248 | 3 | 0 | 3 |
| PTPRE | NPC1 | 0.706385 | 3 | 0 | 3 |
| PTPRE | PLOD1 | 0.688215 | 3 | 0 | 3 |
| PTPRE | SHC1 | 0.684107 | 3 | 0 | 3 |
| PTPRE | MAD2L2 | 0.681339 | 3 | 0 | 3 |
| PTPRE | LYSMD2 | 0.67841 | 3 | 0 | 3 |
| PTPRE | TRPC4 | 0.676984 | 3 | 0 | 3 |
| PTPRE | ACER3 | 0.673026 | 3 | 0 | 3 |
| PTPRE | SLFN12 | 0.671538 | 4 | 0 | 3 |
| PTPRE | PHTF1 | 0.668678 | 4 | 0 | 3 |
| PTPRE | NOL9 | 0.668593 | 3 | 0 | 3 |
| PTPRE | SLC30A7 | 0.653067 | 4 | 0 | 3 |
| PTPRE | HPS4 | 0.651661 | 3 | 0 | 3 |
| PTPRE | ALPK2 | 0.650618 | 3 | 0 | 3 |
| PTPRE | ARPC5 | 0.650012 | 4 | 0 | 3 |
| PTPRE | RHOH | 0.64893 | 3 | 0 | 3 |
| PTPRE | MTMR11 | 0.648534 | 3 | 0 | 3 |
| PTPRE | ZMYM1 | 0.643573 | 3 | 0 | 3 |
| PTPRE | G0S2 | 0.638561 | 3 | 0 | 3 |
| PTPRE | HOMER2 | 0.635599 | 3 | 0 | 3 |
For details and further investigation, click here
