| Full name: NADH:ubiquinone oxidoreductase core subunit S2 | Alias Symbol: CI-49 | ||
| Type: protein-coding gene | Cytoband: 1q23.3 | ||
| Entrez ID: 4720 | HGNC ID: HGNC:7708 | Ensembl Gene: ENSG00000158864 | OMIM ID: 602985 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of NDUFS2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NDUFS2 | 4720 | 201966_at | 0.0856 | 0.7858 | |
| GSE20347 | NDUFS2 | 4720 | 201966_at | 0.0728 | 0.5404 | |
| GSE23400 | NDUFS2 | 4720 | 201966_at | 0.1520 | 0.0009 | |
| GSE26886 | NDUFS2 | 4720 | 201966_at | -0.4351 | 0.0060 | |
| GSE29001 | NDUFS2 | 4720 | 201966_at | -0.0544 | 0.9122 | |
| GSE38129 | NDUFS2 | 4720 | 201966_at | 0.1541 | 0.1704 | |
| GSE45670 | NDUFS2 | 4720 | 201966_at | 0.1596 | 0.1475 | |
| GSE53622 | NDUFS2 | 4720 | 31651 | 0.0520 | 0.3230 | |
| GSE53624 | NDUFS2 | 4720 | 31651 | -0.0320 | 0.7533 | |
| GSE63941 | NDUFS2 | 4720 | 201966_at | 0.3572 | 0.2792 | |
| GSE77861 | NDUFS2 | 4720 | 201966_at | 0.3369 | 0.0209 | |
| GSE97050 | NDUFS2 | 4720 | A_23_P149470 | 0.1119 | 0.5974 | |
| SRP007169 | NDUFS2 | 4720 | RNAseq | -0.3547 | 0.2892 | |
| SRP008496 | NDUFS2 | 4720 | RNAseq | -0.2452 | 0.2184 | |
| SRP064894 | NDUFS2 | 4720 | RNAseq | 0.0179 | 0.8982 | |
| SRP133303 | NDUFS2 | 4720 | RNAseq | -0.0348 | 0.7770 | |
| SRP159526 | NDUFS2 | 4720 | RNAseq | 0.4626 | 0.0592 | |
| SRP193095 | NDUFS2 | 4720 | RNAseq | -0.1456 | 0.1318 | |
| SRP219564 | NDUFS2 | 4720 | RNAseq | -0.1511 | 0.5617 | |
| TCGA | NDUFS2 | 4720 | RNAseq | -0.1209 | 0.0074 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NDUFS2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NDUFS2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NDUFS2 | 4720 | 10 | 0 | 20 | |
| GSE20123 | NDUFS2 | 4720 | 10 | 0 | 20 | |
| GSE43470 | NDUFS2 | 4720 | 7 | 2 | 34 | |
| GSE46452 | NDUFS2 | 4720 | 2 | 1 | 56 | |
| GSE47630 | NDUFS2 | 4720 | 14 | 0 | 26 | |
| GSE54993 | NDUFS2 | 4720 | 0 | 6 | 64 | |
| GSE54994 | NDUFS2 | 4720 | 16 | 0 | 37 | |
| GSE60625 | NDUFS2 | 4720 | 0 | 0 | 11 | |
| GSE74703 | NDUFS2 | 4720 | 7 | 2 | 27 | |
| GSE74704 | NDUFS2 | 4720 | 4 | 0 | 16 | |
| TCGA | NDUFS2 | 4720 | 45 | 3 | 48 |
Total number of gains: 115; Total number of losses: 14; Total Number of normals: 359.
Somatic mutations of NDUFS2:
Generating mutation plots.
Highly correlated genes for NDUFS2:
Showing top 20/594 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NDUFS2 | IFT46 | 0.765754 | 3 | 0 | 3 |
| NDUFS2 | HDAC3 | 0.752073 | 3 | 0 | 3 |
| NDUFS2 | FAM120B | 0.739764 | 3 | 0 | 3 |
| NDUFS2 | PPP1R10 | 0.737165 | 3 | 0 | 3 |
| NDUFS2 | TBC1D8 | 0.736049 | 3 | 0 | 3 |
| NDUFS2 | NEK3 | 0.731998 | 3 | 0 | 3 |
| NDUFS2 | KLHL8 | 0.722545 | 3 | 0 | 3 |
| NDUFS2 | HAS3 | 0.722236 | 3 | 0 | 3 |
| NDUFS2 | TAP1 | 0.721641 | 3 | 0 | 3 |
| NDUFS2 | MED15 | 0.720591 | 3 | 0 | 3 |
| NDUFS2 | FAM102B | 0.712257 | 3 | 0 | 3 |
| NDUFS2 | DYRK2 | 0.710993 | 5 | 0 | 5 |
| NDUFS2 | HLA-E | 0.710079 | 3 | 0 | 3 |
| NDUFS2 | SMC5 | 0.704774 | 3 | 0 | 3 |
| NDUFS2 | DCAF13 | 0.703966 | 3 | 0 | 3 |
| NDUFS2 | TMEM218 | 0.702567 | 4 | 0 | 3 |
| NDUFS2 | CWC25 | 0.70228 | 3 | 0 | 3 |
| NDUFS2 | NAA25 | 0.701344 | 4 | 0 | 3 |
| NDUFS2 | RXRA | 0.700627 | 3 | 0 | 3 |
| NDUFS2 | SMCR8 | 0.698556 | 4 | 0 | 3 |
For details and further investigation, click here
