| Full name: phosphatidylinositol glycan anchor biosynthesis class F | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2p21 | ||
| Entrez ID: 5281 | HGNC ID: HGNC:8962 | Ensembl Gene: ENSG00000151665 | OMIM ID: 600153 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PIGF:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PIGF | 5281 | 205077_s_at | 0.0358 | 0.9538 | |
| GSE20347 | PIGF | 5281 | 205077_s_at | 0.0459 | 0.7919 | |
| GSE23400 | PIGF | 5281 | 205077_s_at | 0.3233 | 0.0001 | |
| GSE26886 | PIGF | 5281 | 205077_s_at | -0.2121 | 0.1694 | |
| GSE29001 | PIGF | 5281 | 205077_s_at | -0.0340 | 0.9033 | |
| GSE38129 | PIGF | 5281 | 205077_s_at | 0.3777 | 0.0070 | |
| GSE45670 | PIGF | 5281 | 205077_s_at | 0.3972 | 0.0066 | |
| GSE53622 | PIGF | 5281 | 56521 | 0.3091 | 0.0000 | |
| GSE53624 | PIGF | 5281 | 56521 | 0.1555 | 0.1429 | |
| GSE63941 | PIGF | 5281 | 205077_s_at | -0.1499 | 0.7411 | |
| GSE77861 | PIGF | 5281 | 205077_s_at | -0.0721 | 0.8024 | |
| GSE97050 | PIGF | 5281 | A_23_P131653 | -0.4402 | 0.3282 | |
| SRP007169 | PIGF | 5281 | RNAseq | 0.2040 | 0.6650 | |
| SRP008496 | PIGF | 5281 | RNAseq | 0.3317 | 0.2733 | |
| SRP064894 | PIGF | 5281 | RNAseq | 0.2661 | 0.1225 | |
| SRP133303 | PIGF | 5281 | RNAseq | 0.2900 | 0.0301 | |
| SRP159526 | PIGF | 5281 | RNAseq | 0.3829 | 0.3678 | |
| SRP193095 | PIGF | 5281 | RNAseq | 0.0008 | 0.9947 | |
| SRP219564 | PIGF | 5281 | RNAseq | 0.2755 | 0.4181 | |
| TCGA | PIGF | 5281 | RNAseq | 0.1075 | 0.1085 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PIGF expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PIGF:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PIGF | 5281 | 10 | 1 | 19 | |
| GSE20123 | PIGF | 5281 | 9 | 1 | 20 | |
| GSE43470 | PIGF | 5281 | 5 | 0 | 38 | |
| GSE46452 | PIGF | 5281 | 1 | 4 | 54 | |
| GSE47630 | PIGF | 5281 | 7 | 0 | 33 | |
| GSE54993 | PIGF | 5281 | 0 | 5 | 65 | |
| GSE54994 | PIGF | 5281 | 10 | 0 | 43 | |
| GSE60625 | PIGF | 5281 | 0 | 3 | 8 | |
| GSE74703 | PIGF | 5281 | 5 | 0 | 31 | |
| GSE74704 | PIGF | 5281 | 9 | 1 | 10 | |
| TCGA | PIGF | 5281 | 35 | 2 | 59 |
Total number of gains: 91; Total number of losses: 17; Total Number of normals: 380.
Somatic mutations of PIGF:
Generating mutation plots.
Highly correlated genes for PIGF:
Showing top 20/618 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PIGF | FEM1B | 0.75846 | 3 | 0 | 3 |
| PIGF | LYRM7 | 0.722874 | 3 | 0 | 3 |
| PIGF | APEH | 0.716982 | 3 | 0 | 3 |
| PIGF | POLI | 0.706846 | 3 | 0 | 3 |
| PIGF | TPM4 | 0.706187 | 3 | 0 | 3 |
| PIGF | LYSMD2 | 0.705641 | 3 | 0 | 3 |
| PIGF | ANKRD50 | 0.705405 | 3 | 0 | 3 |
| PIGF | IREB2 | 0.697649 | 5 | 0 | 3 |
| PIGF | ZNF70 | 0.697315 | 3 | 0 | 3 |
| PIGF | FAHD1 | 0.695629 | 3 | 0 | 3 |
| PIGF | TMTC3 | 0.695423 | 4 | 0 | 3 |
| PIGF | NFKB1 | 0.694866 | 3 | 0 | 3 |
| PIGF | CINP | 0.692726 | 4 | 0 | 4 |
| PIGF | MRPS11 | 0.688963 | 4 | 0 | 3 |
| PIGF | LRRC28 | 0.688874 | 4 | 0 | 3 |
| PIGF | SLFN12 | 0.682917 | 3 | 0 | 3 |
| PIGF | NOA1 | 0.681671 | 4 | 0 | 4 |
| PIGF | GTF3C2 | 0.681539 | 7 | 0 | 6 |
| PIGF | KCTD1 | 0.679063 | 3 | 0 | 3 |
| PIGF | AAGAB | 0.678478 | 4 | 0 | 4 |
For details and further investigation, click here
