| Full name: PWWP domain containing 2B | Alias Symbol: bA432J24.1|FLJ46823 | ||
| Type: protein-coding gene | Cytoband: 10q26.3 | ||
| Entrez ID: 170394 | HGNC ID: HGNC:25150 | Ensembl Gene: ENSG00000171813 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of PWWP2B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PWWP2B | 170394 | 227999_at | -0.0504 | 0.9537 | |
| GSE26886 | PWWP2B | 170394 | 227999_at | -0.4318 | 0.0898 | |
| GSE45670 | PWWP2B | 170394 | 227999_at | -0.4402 | 0.0199 | |
| GSE53622 | PWWP2B | 170394 | 74998 | -0.9279 | 0.0000 | |
| GSE53624 | PWWP2B | 170394 | 74998 | -1.0358 | 0.0000 | |
| GSE63941 | PWWP2B | 170394 | 227999_at | 0.4220 | 0.4293 | |
| GSE77861 | PWWP2B | 170394 | 227999_at | -0.3820 | 0.0477 | |
| GSE97050 | PWWP2B | 170394 | A_23_P374389 | 0.0477 | 0.9128 | |
| SRP007169 | PWWP2B | 170394 | RNAseq | -3.3416 | 0.0000 | |
| SRP008496 | PWWP2B | 170394 | RNAseq | -3.1694 | 0.0000 | |
| SRP064894 | PWWP2B | 170394 | RNAseq | -1.5399 | 0.0000 | |
| SRP133303 | PWWP2B | 170394 | RNAseq | -1.0489 | 0.0000 | |
| SRP159526 | PWWP2B | 170394 | RNAseq | -1.3339 | 0.0001 | |
| SRP193095 | PWWP2B | 170394 | RNAseq | -0.9968 | 0.0000 | |
| SRP219564 | PWWP2B | 170394 | RNAseq | -0.9963 | 0.0481 | |
| TCGA | PWWP2B | 170394 | RNAseq | -0.2267 | 0.0005 |
Upregulated datasets: 0; Downregulated datasets: 6.
Survival by PWWP2B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PWWP2B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PWWP2B | 170394 | 2 | 8 | 20 | |
| GSE20123 | PWWP2B | 170394 | 2 | 9 | 19 | |
| GSE43470 | PWWP2B | 170394 | 0 | 9 | 34 | |
| GSE46452 | PWWP2B | 170394 | 1 | 11 | 47 | |
| GSE47630 | PWWP2B | 170394 | 4 | 13 | 23 | |
| GSE54993 | PWWP2B | 170394 | 8 | 1 | 61 | |
| GSE54994 | PWWP2B | 170394 | 1 | 9 | 43 | |
| GSE60625 | PWWP2B | 170394 | 0 | 0 | 11 | |
| GSE74703 | PWWP2B | 170394 | 0 | 6 | 30 | |
| GSE74704 | PWWP2B | 170394 | 2 | 4 | 14 | |
| TCGA | PWWP2B | 170394 | 7 | 28 | 61 |
Total number of gains: 27; Total number of losses: 98; Total Number of normals: 363.
Somatic mutations of PWWP2B:
Generating mutation plots.
Highly correlated genes for PWWP2B:
Showing top 20/741 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PWWP2B | ADIRF | 0.740218 | 4 | 0 | 4 |
| PWWP2B | TCP11L2 | 0.729421 | 3 | 0 | 3 |
| PWWP2B | ZSWIM8 | 0.726337 | 4 | 0 | 4 |
| PWWP2B | SHROOM3 | 0.72151 | 4 | 0 | 4 |
| PWWP2B | VPS37B | 0.720165 | 5 | 0 | 5 |
| PWWP2B | MUC22 | 0.718732 | 3 | 0 | 3 |
| PWWP2B | SLC37A1 | 0.711252 | 8 | 0 | 8 |
| PWWP2B | TPRN | 0.709123 | 7 | 0 | 7 |
| PWWP2B | MALL | 0.703732 | 5 | 0 | 4 |
| PWWP2B | C1orf116 | 0.70231 | 6 | 0 | 5 |
| PWWP2B | SERPINB6 | 0.698041 | 4 | 0 | 4 |
| PWWP2B | EPS8L2 | 0.695631 | 6 | 0 | 6 |
| PWWP2B | EIF4EBP2 | 0.694625 | 6 | 0 | 6 |
| PWWP2B | NEBL | 0.694622 | 5 | 0 | 5 |
| PWWP2B | FAM214A | 0.693465 | 5 | 0 | 4 |
| PWWP2B | HEBP2 | 0.693418 | 6 | 0 | 6 |
| PWWP2B | MGST2 | 0.691694 | 5 | 0 | 5 |
| PWWP2B | UPK1A | 0.690248 | 6 | 0 | 6 |
| PWWP2B | TDRG1 | 0.689759 | 3 | 0 | 3 |
| PWWP2B | PSCA | 0.689314 | 3 | 0 | 3 |
For details and further investigation, click here
