PAFAH1B3

 

Full name: platelet activating factor acetylhydrolase 1b catalytic subunit 3 Alias Symbol: 
Type: protein-coding gene Cytoband: 19q13.1
Entrez ID: 5050 HGNC ID: HGNC:8576 Ensembl Gene: ENSG00000079462 OMIM ID: 603074
Drug and gene relationship at DGIdb

 

Expression of PAFAH1B3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 PAFAH1B3 5050 203228_at 0.9472 0.0324
GSE20347 PAFAH1B3 5050 203228_at 0.5033 0.0072
GSE23400 PAFAH1B3 5050 203228_at 0.3116 0.0000
GSE26886 PAFAH1B3 5050 203228_at 0.5444 0.0050
GSE29001 PAFAH1B3 5050 203228_at 0.5370 0.2721
GSE38129 PAFAH1B3 5050 203228_at 0.8426 0.0000
GSE45670 PAFAH1B3 5050 203228_at 0.6432 0.0007
GSE53622 PAFAH1B3 5050 80517 0.5455 0.0000
GSE53624 PAFAH1B3 5050 80517 0.5841 0.0000
GSE63941 PAFAH1B3 5050 203228_at 1.2370 0.0174
GSE77861 PAFAH1B3 5050 203228_at 0.2270 0.1845
GSE97050 PAFAH1B3 5050 A_23_P16078 0.4407 0.2492
SRP007169 PAFAH1B3 5050 RNAseq 0.6103 0.1141
SRP008496 PAFAH1B3 5050 RNAseq 0.2967 0.3370
SRP064894 PAFAH1B3 5050 RNAseq 1.7473 0.0001
SRP133303 PAFAH1B3 5050 RNAseq 0.6052 0.0656
SRP159526 PAFAH1B3 5050 RNAseq 1.2684 0.0004
SRP193095 PAFAH1B3 5050 RNAseq 0.4382 0.0160
SRP219564 PAFAH1B3 5050 RNAseq 0.9388 0.0487
TCGA PAFAH1B3 5050 RNAseq 0.4915 0.0000

Upregulated datasets: 3; Downregulated datasets: 0.  

 

Survival by PAFAH1B3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of PAFAH1B3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PAFAH1B3 5050 4 4 22
GSE20123 PAFAH1B3 5050 4 3 23
GSE43470 PAFAH1B3 5050 4 11 28
GSE46452 PAFAH1B3 5050 47 1 11
GSE47630 PAFAH1B3 5050 8 6 26
GSE54993 PAFAH1B3 5050 17 4 49
GSE54994 PAFAH1B3 5050 7 12 34
GSE60625 PAFAH1B3 5050 9 0 2
GSE74703 PAFAH1B3 5050 4 7 25
GSE74704 PAFAH1B3 5050 4 1 15
TCGA PAFAH1B3 5050 13 16 67

Total number of gains: 121; Total number of losses: 65; Total Number of normals: 302.  

 

Somatic mutations of PAFAH1B3:

 

Generating mutation plots.

 

Highly correlated genes for PAFAH1B3:

 

Showing top 20/729 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PAFAH1B3DOCK60.712855303
PAFAH1B3NAPSA0.703729303
PAFAH1B3CD8B0.702297303
PAFAH1B3RNASEH2A0.69935212012
PAFAH1B3C19orf480.697064403
PAFAH1B3INSM10.696779303
PAFAH1B3LIG10.69277412011
PAFAH1B3HPS60.688688303
PAFAH1B3ALDH16A10.688274807
PAFAH1B3MCM50.6877411010
PAFAH1B3KIAA15220.682045303
PAFAH1B3POLR1A0.681776404
PAFAH1B3LSAMP-AS10.676166303
PAFAH1B3UBE2T0.673799707
PAFAH1B3BCL2L120.672495908
PAFAH1B3SHKBP10.670134504
PAFAH1B3CDCA80.66841111010
PAFAH1B3TARBP20.666488908
PAFAH1B3EDARADD0.665495403
PAFAH1B3ASF1B0.6618081109

For details and further investigation, click here