| Full name: aspartate beta-hydroxylase domain containing 2 | Alias Symbol: FLJ39838 | ||
| Type: protein-coding gene | Cytoband: 22q12.1 | ||
| Entrez ID: 57168 | HGNC ID: HGNC:30437 | Ensembl Gene: ENSG00000128203 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ASPHD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ASPHD2 | 57168 | 227014_at | 0.9269 | 0.2968 | |
| GSE26886 | ASPHD2 | 57168 | 227014_at | 0.3118 | 0.4917 | |
| GSE45670 | ASPHD2 | 57168 | 227014_at | 0.6006 | 0.0407 | |
| GSE53622 | ASPHD2 | 57168 | 106484 | 0.4916 | 0.0000 | |
| GSE53624 | ASPHD2 | 57168 | 106484 | 0.4640 | 0.0000 | |
| GSE63941 | ASPHD2 | 57168 | 227014_at | 0.3477 | 0.7089 | |
| GSE77861 | ASPHD2 | 57168 | 227015_at | -0.0835 | 0.6442 | |
| GSE97050 | ASPHD2 | 57168 | A_23_P91640 | 0.2329 | 0.4263 | |
| SRP007169 | ASPHD2 | 57168 | RNAseq | -0.5422 | 0.3607 | |
| SRP064894 | ASPHD2 | 57168 | RNAseq | 0.6468 | 0.0526 | |
| SRP133303 | ASPHD2 | 57168 | RNAseq | 0.7294 | 0.0267 | |
| SRP159526 | ASPHD2 | 57168 | RNAseq | 1.4830 | 0.0020 | |
| SRP193095 | ASPHD2 | 57168 | RNAseq | -0.3212 | 0.4012 | |
| SRP219564 | ASPHD2 | 57168 | RNAseq | 1.3011 | 0.0612 | |
| TCGA | ASPHD2 | 57168 | RNAseq | -0.4693 | 0.0004 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by ASPHD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ASPHD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ASPHD2 | 57168 | 3 | 6 | 21 | |
| GSE20123 | ASPHD2 | 57168 | 3 | 5 | 22 | |
| GSE43470 | ASPHD2 | 57168 | 4 | 6 | 33 | |
| GSE46452 | ASPHD2 | 57168 | 31 | 1 | 27 | |
| GSE47630 | ASPHD2 | 57168 | 8 | 5 | 27 | |
| GSE54993 | ASPHD2 | 57168 | 3 | 6 | 61 | |
| GSE54994 | ASPHD2 | 57168 | 11 | 8 | 34 | |
| GSE60625 | ASPHD2 | 57168 | 5 | 0 | 6 | |
| GSE74703 | ASPHD2 | 57168 | 3 | 5 | 28 | |
| GSE74704 | ASPHD2 | 57168 | 0 | 2 | 18 | |
| TCGA | ASPHD2 | 57168 | 26 | 14 | 56 |
Total number of gains: 97; Total number of losses: 58; Total Number of normals: 333.
Somatic mutations of ASPHD2:
Generating mutation plots.
Highly correlated genes for ASPHD2:
Showing top 20/58 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ASPHD2 | NPPB | 0.704659 | 3 | 0 | 3 |
| ASPHD2 | OPRL1 | 0.664626 | 3 | 0 | 3 |
| ASPHD2 | TMED1 | 0.659507 | 3 | 0 | 3 |
| ASPHD2 | DSG2 | 0.651199 | 3 | 0 | 3 |
| ASPHD2 | LINC00221 | 0.650149 | 3 | 0 | 3 |
| ASPHD2 | PPP5C | 0.637479 | 3 | 0 | 3 |
| ASPHD2 | KRTAP5-7 | 0.634235 | 3 | 0 | 3 |
| ASPHD2 | CHEK2 | 0.633159 | 3 | 0 | 3 |
| ASPHD2 | TRIM46 | 0.621306 | 3 | 0 | 3 |
| ASPHD2 | KIR3DL1 | 0.620448 | 4 | 0 | 3 |
| ASPHD2 | CDHR5 | 0.616404 | 3 | 0 | 3 |
| ASPHD2 | MANEAL | 0.613409 | 3 | 0 | 3 |
| ASPHD2 | CCR8 | 0.604574 | 3 | 0 | 3 |
| ASPHD2 | FCHO1 | 0.602926 | 4 | 0 | 4 |
| ASPHD2 | CD300A | 0.599282 | 3 | 0 | 3 |
| ASPHD2 | SLC19A1 | 0.597839 | 3 | 0 | 3 |
| ASPHD2 | LINC00276 | 0.596651 | 3 | 0 | 3 |
| ASPHD2 | FGF22 | 0.593366 | 3 | 0 | 3 |
| ASPHD2 | SLC26A1 | 0.591785 | 3 | 0 | 3 |
| ASPHD2 | ZNF32-AS3 | 0.581744 | 3 | 0 | 3 |
For details and further investigation, click here
