| Full name: MANSC domain containing 1 | Alias Symbol: FLJ10298|LOH12CR3 | ||
| Type: protein-coding gene | Cytoband: 12p13.2 | ||
| Entrez ID: 54682 | HGNC ID: HGNC:25505 | Ensembl Gene: ENSG00000111261 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of MANSC1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MANSC1 | 54682 | 220945_x_at | -1.3598 | 0.0981 | |
| GSE20347 | MANSC1 | 54682 | 220945_x_at | -1.8812 | 0.0000 | |
| GSE23400 | MANSC1 | 54682 | 220945_x_at | -1.1763 | 0.0000 | |
| GSE26886 | MANSC1 | 54682 | 220945_x_at | -2.4895 | 0.0000 | |
| GSE29001 | MANSC1 | 54682 | 220945_x_at | -1.9259 | 0.0024 | |
| GSE38129 | MANSC1 | 54682 | 220945_x_at | -1.4227 | 0.0000 | |
| GSE45670 | MANSC1 | 54682 | 220945_x_at | -0.4891 | 0.1146 | |
| GSE53622 | MANSC1 | 54682 | 140318 | -1.2663 | 0.0000 | |
| GSE53624 | MANSC1 | 54682 | 140318 | -1.5011 | 0.0000 | |
| GSE63941 | MANSC1 | 54682 | 220945_x_at | -2.0521 | 0.2757 | |
| GSE77861 | MANSC1 | 54682 | 220945_x_at | -0.6028 | 0.3441 | |
| GSE97050 | MANSC1 | 54682 | A_23_P162211 | -0.4392 | 0.2451 | |
| SRP007169 | MANSC1 | 54682 | RNAseq | -1.5670 | 0.0013 | |
| SRP008496 | MANSC1 | 54682 | RNAseq | -1.7400 | 0.0000 | |
| SRP064894 | MANSC1 | 54682 | RNAseq | -1.6105 | 0.0000 | |
| SRP133303 | MANSC1 | 54682 | RNAseq | -0.9699 | 0.0002 | |
| SRP159526 | MANSC1 | 54682 | RNAseq | -0.7567 | 0.0579 | |
| SRP193095 | MANSC1 | 54682 | RNAseq | -1.0754 | 0.0000 | |
| SRP219564 | MANSC1 | 54682 | RNAseq | -1.5287 | 0.0038 | |
| TCGA | MANSC1 | 54682 | RNAseq | -0.2680 | 0.0785 |
Upregulated datasets: 0; Downregulated datasets: 12.
Survival by MANSC1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MANSC1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MANSC1 | 54682 | 6 | 2 | 22 | |
| GSE20123 | MANSC1 | 54682 | 6 | 2 | 22 | |
| GSE43470 | MANSC1 | 54682 | 10 | 4 | 29 | |
| GSE46452 | MANSC1 | 54682 | 10 | 1 | 48 | |
| GSE47630 | MANSC1 | 54682 | 13 | 2 | 25 | |
| GSE54993 | MANSC1 | 54682 | 2 | 9 | 59 | |
| GSE54994 | MANSC1 | 54682 | 10 | 2 | 41 | |
| GSE60625 | MANSC1 | 54682 | 0 | 1 | 10 | |
| GSE74703 | MANSC1 | 54682 | 9 | 3 | 24 | |
| GSE74704 | MANSC1 | 54682 | 4 | 1 | 15 | |
| TCGA | MANSC1 | 54682 | 39 | 7 | 50 |
Total number of gains: 109; Total number of losses: 34; Total Number of normals: 345.
Somatic mutations of MANSC1:
Generating mutation plots.
Highly correlated genes for MANSC1:
Showing top 20/1402 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MANSC1 | SLC10A5 | 0.772472 | 3 | 0 | 3 |
| MANSC1 | GALNT12 | 0.766635 | 11 | 0 | 11 |
| MANSC1 | PPFIBP2 | 0.764515 | 11 | 0 | 11 |
| MANSC1 | SAMD5 | 0.753475 | 6 | 0 | 6 |
| MANSC1 | GLTP | 0.742758 | 9 | 0 | 9 |
| MANSC1 | MTM1 | 0.742724 | 3 | 0 | 3 |
| MANSC1 | FAM3B | 0.742017 | 6 | 0 | 6 |
| MANSC1 | ELMOD2 | 0.732323 | 3 | 0 | 3 |
| MANSC1 | SASH1 | 0.728786 | 11 | 0 | 11 |
| MANSC1 | TGM3 | 0.728126 | 10 | 0 | 10 |
| MANSC1 | CA13 | 0.722158 | 3 | 0 | 3 |
| MANSC1 | NUCB2 | 0.718199 | 11 | 0 | 10 |
| MANSC1 | ELOVL6 | 0.717088 | 11 | 0 | 11 |
| MANSC1 | SLC16A6 | 0.715711 | 11 | 0 | 11 |
| MANSC1 | ABLIM1 | 0.714881 | 11 | 0 | 11 |
| MANSC1 | ZDHHC13 | 0.714391 | 11 | 0 | 11 |
| MANSC1 | SLC16A14 | 0.714278 | 6 | 0 | 6 |
| MANSC1 | TAB3 | 0.713856 | 6 | 0 | 6 |
| MANSC1 | TM7SF2 | 0.713838 | 11 | 0 | 11 |
| MANSC1 | ZDHHC21 | 0.71254 | 6 | 0 | 5 |
For details and further investigation, click here
