| Full name: PPFIA binding protein 2 | Alias Symbol: Cclp1 | ||
| Type: protein-coding gene | Cytoband: 11p15.4 | ||
| Entrez ID: 8495 | HGNC ID: HGNC:9250 | Ensembl Gene: ENSG00000166387 | OMIM ID: 603142 |
| Drug and gene relationship at DGIdb | |||
Expression of PPFIBP2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PPFIBP2 | 8495 | 212841_s_at | -0.7916 | 0.2087 | |
| GSE20347 | PPFIBP2 | 8495 | 212841_s_at | -1.5066 | 0.0000 | |
| GSE23400 | PPFIBP2 | 8495 | 212841_s_at | -0.8037 | 0.0000 | |
| GSE26886 | PPFIBP2 | 8495 | 212841_s_at | -1.2409 | 0.0022 | |
| GSE29001 | PPFIBP2 | 8495 | 212841_s_at | -1.3386 | 0.0097 | |
| GSE38129 | PPFIBP2 | 8495 | 212841_s_at | -1.1769 | 0.0000 | |
| GSE45670 | PPFIBP2 | 8495 | 212841_s_at | -0.4784 | 0.0754 | |
| GSE53622 | PPFIBP2 | 8495 | 43079 | -1.1122 | 0.0000 | |
| GSE53624 | PPFIBP2 | 8495 | 43079 | -1.5064 | 0.0000 | |
| GSE63941 | PPFIBP2 | 8495 | 212841_s_at | 0.2578 | 0.7749 | |
| GSE77861 | PPFIBP2 | 8495 | 212841_s_at | -0.8592 | 0.0372 | |
| GSE97050 | PPFIBP2 | 8495 | A_23_P409623 | -0.2235 | 0.5259 | |
| SRP007169 | PPFIBP2 | 8495 | RNAseq | -2.0130 | 0.0000 | |
| SRP008496 | PPFIBP2 | 8495 | RNAseq | -1.8788 | 0.0000 | |
| SRP064894 | PPFIBP2 | 8495 | RNAseq | -1.3308 | 0.0000 | |
| SRP133303 | PPFIBP2 | 8495 | RNAseq | -0.9167 | 0.0023 | |
| SRP159526 | PPFIBP2 | 8495 | RNAseq | -1.0821 | 0.0000 | |
| SRP193095 | PPFIBP2 | 8495 | RNAseq | -1.1540 | 0.0000 | |
| SRP219564 | PPFIBP2 | 8495 | RNAseq | -1.3162 | 0.0114 | |
| TCGA | PPFIBP2 | 8495 | RNAseq | -0.4407 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 12.
Survival by PPFIBP2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PPFIBP2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PPFIBP2 | 8495 | 0 | 11 | 19 | |
| GSE20123 | PPFIBP2 | 8495 | 0 | 11 | 19 | |
| GSE43470 | PPFIBP2 | 8495 | 1 | 8 | 34 | |
| GSE46452 | PPFIBP2 | 8495 | 7 | 8 | 44 | |
| GSE47630 | PPFIBP2 | 8495 | 2 | 12 | 26 | |
| GSE54993 | PPFIBP2 | 8495 | 3 | 1 | 66 | |
| GSE54994 | PPFIBP2 | 8495 | 2 | 12 | 39 | |
| GSE60625 | PPFIBP2 | 8495 | 0 | 0 | 11 | |
| GSE74703 | PPFIBP2 | 8495 | 1 | 6 | 29 | |
| GSE74704 | PPFIBP2 | 8495 | 0 | 9 | 11 | |
| TCGA | PPFIBP2 | 8495 | 9 | 37 | 50 |
Total number of gains: 25; Total number of losses: 115; Total Number of normals: 348.
Somatic mutations of PPFIBP2:
Generating mutation plots.
Highly correlated genes for PPFIBP2:
Showing top 20/1627 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PPFIBP2 | LRRC28 | 0.791783 | 3 | 0 | 3 |
| PPFIBP2 | SLC10A5 | 0.79049 | 3 | 0 | 3 |
| PPFIBP2 | ULK3 | 0.781897 | 7 | 0 | 7 |
| PPFIBP2 | ZNF823 | 0.776377 | 7 | 0 | 7 |
| PPFIBP2 | MYO5B | 0.77597 | 6 | 0 | 6 |
| PPFIBP2 | GALNT12 | 0.772885 | 11 | 0 | 11 |
| PPFIBP2 | ARHGAP27 | 0.772297 | 7 | 0 | 7 |
| PPFIBP2 | EPS15 | 0.767119 | 4 | 0 | 4 |
| PPFIBP2 | KIAA1211L | 0.766124 | 6 | 0 | 6 |
| PPFIBP2 | HDHD2 | 0.766117 | 4 | 0 | 4 |
| PPFIBP2 | CCNYL1 | 0.765965 | 5 | 0 | 4 |
| PPFIBP2 | MANSC1 | 0.764515 | 11 | 0 | 11 |
| PPFIBP2 | UBL3 | 0.760422 | 10 | 0 | 10 |
| PPFIBP2 | RNF141 | 0.758009 | 11 | 0 | 11 |
| PPFIBP2 | BLNK | 0.756351 | 11 | 0 | 11 |
| PPFIBP2 | TTC9 | 0.755557 | 11 | 0 | 11 |
| PPFIBP2 | SASH1 | 0.754703 | 11 | 0 | 11 |
| PPFIBP2 | RAB25 | 0.754601 | 11 | 0 | 11 |
| PPFIBP2 | TPRN | 0.751921 | 4 | 0 | 4 |
| PPFIBP2 | SAMD5 | 0.748197 | 7 | 0 | 7 |
For details and further investigation, click here
