| Full name: ELOVL fatty acid elongase 6 | Alias Symbol: FLJ23378|MGC5487|LCE | ||
| Type: protein-coding gene | Cytoband: 4q25 | ||
| Entrez ID: 79071 | HGNC ID: HGNC:15829 | Ensembl Gene: ENSG00000170522 | OMIM ID: 611546 |
| Drug and gene relationship at DGIdb | |||
Expression of ELOVL6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ELOVL6 | 79071 | 204256_at | -0.8962 | 0.3977 | |
| GSE20347 | ELOVL6 | 79071 | 204256_at | -2.1366 | 0.0000 | |
| GSE23400 | ELOVL6 | 79071 | 204256_at | -1.4223 | 0.0000 | |
| GSE26886 | ELOVL6 | 79071 | 204256_at | -2.4511 | 0.0000 | |
| GSE29001 | ELOVL6 | 79071 | 204256_at | -1.9984 | 0.0001 | |
| GSE38129 | ELOVL6 | 79071 | 204256_at | -1.2854 | 0.0004 | |
| GSE45670 | ELOVL6 | 79071 | 204256_at | -0.5568 | 0.1499 | |
| GSE53622 | ELOVL6 | 79071 | 30469 | -1.4686 | 0.0000 | |
| GSE53624 | ELOVL6 | 79071 | 30469 | -1.5139 | 0.0000 | |
| GSE63941 | ELOVL6 | 79071 | 204256_at | -0.2392 | 0.7746 | |
| GSE77861 | ELOVL6 | 79071 | 204256_at | -1.0694 | 0.0206 | |
| GSE97050 | ELOVL6 | 79071 | A_23_P7361 | -0.5121 | 0.3252 | |
| SRP007169 | ELOVL6 | 79071 | RNAseq | -1.5038 | 0.0038 | |
| SRP008496 | ELOVL6 | 79071 | RNAseq | -1.9228 | 0.0000 | |
| SRP064894 | ELOVL6 | 79071 | RNAseq | -1.7671 | 0.0000 | |
| SRP133303 | ELOVL6 | 79071 | RNAseq | -0.4337 | 0.3024 | |
| SRP159526 | ELOVL6 | 79071 | RNAseq | -1.7407 | 0.0000 | |
| SRP193095 | ELOVL6 | 79071 | RNAseq | -1.5478 | 0.0000 | |
| SRP219564 | ELOVL6 | 79071 | RNAseq | -1.6171 | 0.0123 | |
| TCGA | ELOVL6 | 79071 | RNAseq | -0.2264 | 0.0500 |
Upregulated datasets: 0; Downregulated datasets: 14.
Survival by ELOVL6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ELOVL6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ELOVL6 | 79071 | 1 | 12 | 17 | |
| GSE20123 | ELOVL6 | 79071 | 1 | 12 | 17 | |
| GSE43470 | ELOVL6 | 79071 | 0 | 13 | 30 | |
| GSE46452 | ELOVL6 | 79071 | 1 | 36 | 22 | |
| GSE47630 | ELOVL6 | 79071 | 0 | 20 | 20 | |
| GSE54993 | ELOVL6 | 79071 | 9 | 0 | 61 | |
| GSE54994 | ELOVL6 | 79071 | 1 | 10 | 42 | |
| GSE60625 | ELOVL6 | 79071 | 0 | 3 | 8 | |
| GSE74703 | ELOVL6 | 79071 | 0 | 11 | 25 | |
| GSE74704 | ELOVL6 | 79071 | 0 | 6 | 14 | |
| TCGA | ELOVL6 | 79071 | 8 | 35 | 53 |
Total number of gains: 21; Total number of losses: 158; Total Number of normals: 309.
Somatic mutations of ELOVL6:
Generating mutation plots.
Highly correlated genes for ELOVL6:
Showing top 20/1581 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ELOVL6 | TPRG1 | 0.790222 | 7 | 0 | 7 |
| ELOVL6 | CA13 | 0.785804 | 3 | 0 | 3 |
| ELOVL6 | CAPN14 | 0.782442 | 6 | 0 | 6 |
| ELOVL6 | CEACAM5 | 0.781781 | 10 | 0 | 10 |
| ELOVL6 | KLB | 0.778955 | 6 | 0 | 6 |
| ELOVL6 | PLEKHA7 | 0.777323 | 7 | 0 | 7 |
| ELOVL6 | ULK3 | 0.77708 | 7 | 0 | 7 |
| ELOVL6 | USP6NL | 0.771887 | 11 | 0 | 11 |
| ELOVL6 | TTC9 | 0.77045 | 11 | 0 | 11 |
| ELOVL6 | SLC16A6 | 0.767908 | 11 | 0 | 11 |
| ELOVL6 | CHP1 | 0.766482 | 10 | 0 | 10 |
| ELOVL6 | CYSRT1 | 0.765781 | 6 | 0 | 6 |
| ELOVL6 | FLG-AS1 | 0.765407 | 6 | 0 | 6 |
| ELOVL6 | SMAGP | 0.764569 | 10 | 0 | 10 |
| ELOVL6 | ARHGAP27 | 0.763934 | 7 | 0 | 7 |
| ELOVL6 | CYP2C18 | 0.762455 | 10 | 0 | 10 |
| ELOVL6 | TM7SF2 | 0.76205 | 11 | 0 | 11 |
| ELOVL6 | SLC10A5 | 0.761687 | 3 | 0 | 3 |
| ELOVL6 | MGST2 | 0.761217 | 11 | 0 | 11 |
| ELOVL6 | SH3PXD2A-AS1 | 0.757967 | 4 | 0 | 4 |
For details and further investigation, click here
