| Full name: microtubule associated protein 1 light chain 3 beta 2 | Alias Symbol: ATG8G | ||
| Type: protein-coding gene | Cytoband: 12q24.22 | ||
| Entrez ID: 643246 | HGNC ID: HGNC:34390 | Ensembl Gene: ENSG00000258102 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of MAP1LC3B2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MAP1LC3B2 | 643246 | 234238_at | 0.0652 | 0.8368 | |
| GSE26886 | MAP1LC3B2 | 643246 | 234238_at | 0.2147 | 0.1091 | |
| GSE45670 | MAP1LC3B2 | 643246 | 234238_at | 0.0787 | 0.4500 | |
| GSE63941 | MAP1LC3B2 | 643246 | 234238_at | 0.0800 | 0.5708 | |
| GSE77861 | MAP1LC3B2 | 643246 | 234238_at | -0.1114 | 0.3238 | |
| SRP007169 | MAP1LC3B2 | 643246 | RNAseq | -1.7641 | 0.0084 | |
| TCGA | MAP1LC3B2 | 643246 | RNAseq | -0.0365 | 0.5360 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by MAP1LC3B2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of MAP1LC3B2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MAP1LC3B2 | 643246 | 4 | 3 | 23 | |
| GSE20123 | MAP1LC3B2 | 643246 | 4 | 3 | 23 | |
| GSE43470 | MAP1LC3B2 | 643246 | 2 | 0 | 41 | |
| GSE46452 | MAP1LC3B2 | 643246 | 9 | 1 | 49 | |
| GSE47630 | MAP1LC3B2 | 643246 | 9 | 3 | 28 | |
| GSE54993 | MAP1LC3B2 | 643246 | 0 | 5 | 65 | |
| GSE54994 | MAP1LC3B2 | 643246 | 6 | 5 | 42 | |
| GSE60625 | MAP1LC3B2 | 643246 | 0 | 0 | 11 | |
| GSE74703 | MAP1LC3B2 | 643246 | 2 | 0 | 34 | |
| GSE74704 | MAP1LC3B2 | 643246 | 2 | 2 | 16 | |
| TCGA | MAP1LC3B2 | 643246 | 22 | 10 | 64 |
Total number of gains: 60; Total number of losses: 32; Total Number of normals: 396.
Somatic mutations of MAP1LC3B2:
Generating mutation plots.
Highly correlated genes for MAP1LC3B2:
Showing top 20/45 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MAP1LC3B2 | ATP1A3 | 0.749787 | 3 | 0 | 3 |
| MAP1LC3B2 | NSMF | 0.690219 | 3 | 0 | 3 |
| MAP1LC3B2 | FGF21 | 0.689351 | 3 | 0 | 3 |
| MAP1LC3B2 | HDAC10 | 0.675346 | 3 | 0 | 3 |
| MAP1LC3B2 | KAAG1 | 0.669024 | 3 | 0 | 3 |
| MAP1LC3B2 | PHOX2A | 0.662769 | 3 | 0 | 3 |
| MAP1LC3B2 | PRSS37 | 0.648428 | 3 | 0 | 3 |
| MAP1LC3B2 | FGF17 | 0.635371 | 3 | 0 | 3 |
| MAP1LC3B2 | MEPE | 0.634713 | 3 | 0 | 3 |
| MAP1LC3B2 | C12orf40 | 0.634486 | 3 | 0 | 3 |
| MAP1LC3B2 | LINC00311 | 0.626997 | 3 | 0 | 3 |
| MAP1LC3B2 | USP2-AS1 | 0.626374 | 3 | 0 | 3 |
| MAP1LC3B2 | MYOG | 0.624736 | 3 | 0 | 3 |
| MAP1LC3B2 | SEZ6L2 | 0.623944 | 3 | 0 | 3 |
| MAP1LC3B2 | GLI1 | 0.621757 | 3 | 0 | 3 |
| MAP1LC3B2 | BTNL3 | 0.614144 | 3 | 0 | 3 |
| MAP1LC3B2 | CIB3 | 0.610103 | 3 | 0 | 3 |
| MAP1LC3B2 | VPS13A-AS1 | 0.603642 | 4 | 0 | 3 |
| MAP1LC3B2 | SP8 | 0.602351 | 3 | 0 | 3 |
| MAP1LC3B2 | CHST13 | 0.602137 | 3 | 0 | 3 |
For details and further investigation, click here
