| Full name: paired like homeobox 2A | Alias Symbol: PMX2A|CFEOM2 | ||
| Type: protein-coding gene | Cytoband: 11q13.4 | ||
| Entrez ID: 401 | HGNC ID: HGNC:691 | Ensembl Gene: ENSG00000165462 | OMIM ID: 602753 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PHOX2A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PHOX2A | 401 | 214609_at | 0.0918 | 0.7909 | |
| GSE20347 | PHOX2A | 401 | 214609_at | -0.0830 | 0.2782 | |
| GSE23400 | PHOX2A | 401 | 214609_at | -0.0257 | 0.4435 | |
| GSE26886 | PHOX2A | 401 | 214609_at | 0.4331 | 0.0011 | |
| GSE29001 | PHOX2A | 401 | 214609_at | -0.0935 | 0.5244 | |
| GSE38129 | PHOX2A | 401 | 214609_at | -0.1211 | 0.0860 | |
| GSE45670 | PHOX2A | 401 | 214609_at | 0.0248 | 0.7852 | |
| GSE53622 | PHOX2A | 401 | 107540 | 0.0931 | 0.6292 | |
| GSE53624 | PHOX2A | 401 | 107540 | 0.4755 | 0.0038 | |
| GSE63941 | PHOX2A | 401 | 214609_at | 0.1755 | 0.2500 | |
| GSE77861 | PHOX2A | 401 | 214609_at | -0.0597 | 0.7216 | |
| TCGA | PHOX2A | 401 | RNAseq | -2.0159 | 0.1232 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PHOX2A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PHOX2A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PHOX2A | 401 | 10 | 7 | 13 | |
| GSE20123 | PHOX2A | 401 | 10 | 7 | 13 | |
| GSE43470 | PHOX2A | 401 | 9 | 4 | 30 | |
| GSE46452 | PHOX2A | 401 | 12 | 17 | 30 | |
| GSE47630 | PHOX2A | 401 | 10 | 10 | 20 | |
| GSE54993 | PHOX2A | 401 | 7 | 3 | 60 | |
| GSE54994 | PHOX2A | 401 | 11 | 13 | 29 | |
| GSE60625 | PHOX2A | 401 | 0 | 7 | 4 | |
| GSE74703 | PHOX2A | 401 | 7 | 3 | 26 | |
| GSE74704 | PHOX2A | 401 | 7 | 4 | 9 | |
| TCGA | PHOX2A | 401 | 35 | 20 | 41 |
Total number of gains: 118; Total number of losses: 95; Total Number of normals: 275.
Somatic mutations of PHOX2A:
Generating mutation plots.
Highly correlated genes for PHOX2A:
Showing top 20/352 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PHOX2A | KLK14 | 0.720801 | 3 | 0 | 3 |
| PHOX2A | DBH | 0.7098 | 4 | 0 | 3 |
| PHOX2A | CST8 | 0.69594 | 4 | 0 | 4 |
| PHOX2A | C19orf81 | 0.690826 | 3 | 0 | 3 |
| PHOX2A | TMEM51-AS1 | 0.684856 | 3 | 0 | 3 |
| PHOX2A | DGCR10 | 0.684816 | 3 | 0 | 3 |
| PHOX2A | COL19A1 | 0.674632 | 4 | 0 | 3 |
| PHOX2A | NXNL1 | 0.665767 | 3 | 0 | 3 |
| PHOX2A | MAP1LC3B2 | 0.662769 | 3 | 0 | 3 |
| PHOX2A | ZNF358 | 0.662409 | 3 | 0 | 3 |
| PHOX2A | MOGAT3 | 0.659027 | 3 | 0 | 3 |
| PHOX2A | FUZ | 0.658248 | 3 | 0 | 3 |
| PHOX2A | DHRS7C | 0.657589 | 3 | 0 | 3 |
| PHOX2A | SPAG6 | 0.651856 | 3 | 0 | 3 |
| PHOX2A | CCR4 | 0.650864 | 3 | 0 | 3 |
| PHOX2A | CABIN1 | 0.647891 | 3 | 0 | 3 |
| PHOX2A | MAPK11 | 0.642943 | 3 | 0 | 3 |
| PHOX2A | HK3 | 0.642158 | 3 | 0 | 3 |
| PHOX2A | RPH3A | 0.637446 | 4 | 0 | 3 |
| PHOX2A | AMBRA1 | 0.634899 | 3 | 0 | 3 |
For details and further investigation, click here
