| Full name: MAPK associated protein 1 | Alias Symbol: MGC2745|SIN1|MIP1 | ||
| Type: protein-coding gene | Cytoband: 9q33.3 | ||
| Entrez ID: 79109 | HGNC ID: HGNC:18752 | Ensembl Gene: ENSG00000119487 | OMIM ID: 610558 |
| Drug and gene relationship at DGIdb | |||
Expression of MAPKAP1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MAPKAP1 | 79109 | 217808_s_at | 0.0105 | 0.9781 | |
| GSE20347 | MAPKAP1 | 79109 | 217808_s_at | -0.1948 | 0.1968 | |
| GSE23400 | MAPKAP1 | 79109 | 217808_s_at | 0.2042 | 0.0058 | |
| GSE26886 | MAPKAP1 | 79109 | 217808_s_at | -0.0081 | 0.9718 | |
| GSE29001 | MAPKAP1 | 79109 | 217808_s_at | -0.0220 | 0.9584 | |
| GSE38129 | MAPKAP1 | 79109 | 217808_s_at | -0.0636 | 0.6270 | |
| GSE45670 | MAPKAP1 | 79109 | 217808_s_at | 0.1198 | 0.3327 | |
| GSE53622 | MAPKAP1 | 79109 | 90127 | 0.1586 | 0.0120 | |
| GSE53624 | MAPKAP1 | 79109 | 90127 | 0.3075 | 0.0000 | |
| GSE63941 | MAPKAP1 | 79109 | 217808_s_at | 0.1165 | 0.7653 | |
| GSE77861 | MAPKAP1 | 79109 | 217808_s_at | 0.1821 | 0.3534 | |
| GSE97050 | MAPKAP1 | 79109 | A_33_P3251538 | 0.0213 | 0.9381 | |
| SRP007169 | MAPKAP1 | 79109 | RNAseq | -0.3724 | 0.3512 | |
| SRP008496 | MAPKAP1 | 79109 | RNAseq | -0.2325 | 0.3047 | |
| SRP064894 | MAPKAP1 | 79109 | RNAseq | 0.1894 | 0.1851 | |
| SRP133303 | MAPKAP1 | 79109 | RNAseq | 0.3370 | 0.0588 | |
| SRP159526 | MAPKAP1 | 79109 | RNAseq | 0.1528 | 0.3981 | |
| SRP193095 | MAPKAP1 | 79109 | RNAseq | -0.0401 | 0.6615 | |
| SRP219564 | MAPKAP1 | 79109 | RNAseq | -0.2977 | 0.4607 | |
| TCGA | MAPKAP1 | 79109 | RNAseq | -0.0578 | 0.1937 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MAPKAP1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MAPKAP1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MAPKAP1 | 79109 | 4 | 8 | 18 | |
| GSE20123 | MAPKAP1 | 79109 | 4 | 8 | 18 | |
| GSE43470 | MAPKAP1 | 79109 | 5 | 6 | 32 | |
| GSE46452 | MAPKAP1 | 79109 | 6 | 13 | 40 | |
| GSE47630 | MAPKAP1 | 79109 | 3 | 16 | 21 | |
| GSE54993 | MAPKAP1 | 79109 | 3 | 3 | 64 | |
| GSE54994 | MAPKAP1 | 79109 | 12 | 9 | 32 | |
| GSE60625 | MAPKAP1 | 79109 | 0 | 0 | 11 | |
| GSE74703 | MAPKAP1 | 79109 | 5 | 4 | 27 | |
| GSE74704 | MAPKAP1 | 79109 | 2 | 6 | 12 | |
| TCGA | MAPKAP1 | 79109 | 27 | 25 | 44 |
Total number of gains: 71; Total number of losses: 98; Total Number of normals: 319.
Somatic mutations of MAPKAP1:
Generating mutation plots.
Highly correlated genes for MAPKAP1:
Showing top 20/190 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MAPKAP1 | NKX6-2 | 0.822165 | 3 | 0 | 3 |
| MAPKAP1 | HDAC3 | 0.789837 | 3 | 0 | 3 |
| MAPKAP1 | TRPC4AP | 0.765255 | 3 | 0 | 3 |
| MAPKAP1 | TFDP2 | 0.726023 | 3 | 0 | 3 |
| MAPKAP1 | LIPT1 | 0.72399 | 3 | 0 | 3 |
| MAPKAP1 | GOLGB1 | 0.714183 | 3 | 0 | 3 |
| MAPKAP1 | ACAP2 | 0.702587 | 3 | 0 | 3 |
| MAPKAP1 | AGBL5 | 0.698589 | 3 | 0 | 3 |
| MAPKAP1 | NDUFA9 | 0.696609 | 3 | 0 | 3 |
| MAPKAP1 | PRCC | 0.696232 | 3 | 0 | 3 |
| MAPKAP1 | UBE2L3 | 0.694064 | 4 | 0 | 4 |
| MAPKAP1 | REST | 0.690428 | 3 | 0 | 3 |
| MAPKAP1 | UQCR10 | 0.680518 | 5 | 0 | 4 |
| MAPKAP1 | KLHDC2 | 0.67863 | 3 | 0 | 3 |
| MAPKAP1 | RBM23 | 0.67795 | 4 | 0 | 3 |
| MAPKAP1 | NDUFA13 | 0.670922 | 4 | 0 | 4 |
| MAPKAP1 | ATP6V1E1 | 0.670921 | 5 | 0 | 5 |
| MAPKAP1 | APPL2 | 0.669001 | 3 | 0 | 3 |
| MAPKAP1 | PSMG2 | 0.667989 | 6 | 0 | 5 |
| MAPKAP1 | NUS1 | 0.667741 | 3 | 0 | 3 |
For details and further investigation, click here
