| Full name: proteasome assembly chaperone 2 | Alias Symbol: HCCA3|MDS003|MGC15092|CLAST3|HsT1707|PAC2 | ||
| Type: protein-coding gene | Cytoband: 18p11.21 | ||
| Entrez ID: 56984 | HGNC ID: HGNC:24929 | Ensembl Gene: ENSG00000128789 | OMIM ID: 609702 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of PSMG2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PSMG2 | 56984 | 218467_at | -0.0173 | 0.9822 | |
| GSE20347 | PSMG2 | 56984 | 218467_at | -0.3234 | 0.0389 | |
| GSE23400 | PSMG2 | 56984 | 218467_at | 0.0327 | 0.6655 | |
| GSE26886 | PSMG2 | 56984 | 218467_at | -0.1852 | 0.4031 | |
| GSE29001 | PSMG2 | 56984 | 218467_at | -0.1352 | 0.6991 | |
| GSE38129 | PSMG2 | 56984 | 218467_at | -0.1311 | 0.3259 | |
| GSE45670 | PSMG2 | 56984 | 218467_at | -0.2538 | 0.0070 | |
| GSE53622 | PSMG2 | 56984 | 94260 | -0.3059 | 0.0000 | |
| GSE53624 | PSMG2 | 56984 | 94260 | -0.2175 | 0.0013 | |
| GSE63941 | PSMG2 | 56984 | 218467_at | 0.0670 | 0.8813 | |
| GSE77861 | PSMG2 | 56984 | 218467_at | -0.2054 | 0.3671 | |
| GSE97050 | PSMG2 | 56984 | A_24_P399362 | -0.1167 | 0.7720 | |
| SRP007169 | PSMG2 | 56984 | RNAseq | -0.6358 | 0.0326 | |
| SRP008496 | PSMG2 | 56984 | RNAseq | -0.6809 | 0.0024 | |
| SRP064894 | PSMG2 | 56984 | RNAseq | -0.1640 | 0.2671 | |
| SRP133303 | PSMG2 | 56984 | RNAseq | -0.1360 | 0.3142 | |
| SRP159526 | PSMG2 | 56984 | RNAseq | -0.4145 | 0.0373 | |
| SRP193095 | PSMG2 | 56984 | RNAseq | -0.5170 | 0.0001 | |
| SRP219564 | PSMG2 | 56984 | RNAseq | -0.6294 | 0.0075 | |
| TCGA | PSMG2 | 56984 | RNAseq | 0.0489 | 0.3410 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PSMG2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PSMG2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PSMG2 | 56984 | 5 | 3 | 22 | |
| GSE20123 | PSMG2 | 56984 | 5 | 3 | 22 | |
| GSE43470 | PSMG2 | 56984 | 0 | 6 | 37 | |
| GSE46452 | PSMG2 | 56984 | 3 | 21 | 35 | |
| GSE47630 | PSMG2 | 56984 | 7 | 17 | 16 | |
| GSE54993 | PSMG2 | 56984 | 6 | 2 | 62 | |
| GSE54994 | PSMG2 | 56984 | 8 | 8 | 37 | |
| GSE60625 | PSMG2 | 56984 | 0 | 4 | 7 | |
| GSE74703 | PSMG2 | 56984 | 0 | 4 | 32 | |
| GSE74704 | PSMG2 | 56984 | 3 | 2 | 15 | |
| TCGA | PSMG2 | 56984 | 29 | 23 | 44 |
Total number of gains: 66; Total number of losses: 93; Total Number of normals: 329.
Somatic mutations of PSMG2:
Generating mutation plots.
Highly correlated genes for PSMG2:
Showing top 20/335 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PSMG2 | TRAPPC6B | 0.820871 | 3 | 0 | 3 |
| PSMG2 | POLR3C | 0.756728 | 3 | 0 | 3 |
| PSMG2 | NDUFV2 | 0.73586 | 10 | 0 | 10 |
| PSMG2 | UROS | 0.728301 | 3 | 0 | 3 |
| PSMG2 | ABHD2 | 0.723986 | 3 | 0 | 3 |
| PSMG2 | ECD | 0.712565 | 3 | 0 | 3 |
| PSMG2 | CEP63 | 0.704531 | 3 | 0 | 3 |
| PSMG2 | PIBF1 | 0.701055 | 4 | 0 | 3 |
| PSMG2 | COMMD5 | 0.697473 | 3 | 0 | 3 |
| PSMG2 | NCKAP1 | 0.697225 | 4 | 0 | 3 |
| PSMG2 | CRBN | 0.686468 | 4 | 0 | 4 |
| PSMG2 | MOCS2 | 0.682234 | 3 | 0 | 3 |
| PSMG2 | TSEN2 | 0.681492 | 4 | 0 | 3 |
| PSMG2 | NDUFB1 | 0.680607 | 3 | 0 | 3 |
| PSMG2 | PITRM1 | 0.679763 | 3 | 0 | 3 |
| PSMG2 | PPP2R5C | 0.679244 | 4 | 0 | 3 |
| PSMG2 | VAPA | 0.675691 | 11 | 0 | 9 |
| PSMG2 | ANKRA2 | 0.673621 | 3 | 0 | 3 |
| PSMG2 | ZNF268 | 0.673338 | 5 | 0 | 5 |
| PSMG2 | ZNF345 | 0.668997 | 3 | 0 | 3 |
For details and further investigation, click here
