| Full name: MAS1 proto-oncogene like, G protein-coupled receptor | Alias Symbol: MAS-L|MRG|dJ994E9.2 | ||
| Type: protein-coding gene | Cytoband: 6p22.1 | ||
| Entrez ID: 116511 | HGNC ID: HGNC:13961 | Ensembl Gene: ENSG00000204687 | OMIM ID: 607235 |
| Drug and gene relationship at DGIdb | |||
Expression of MAS1L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MAS1L | 116511 | 234820_at | -0.1035 | 0.7075 | |
| GSE26886 | MAS1L | 116511 | 234820_at | -0.1892 | 0.1567 | |
| GSE45670 | MAS1L | 116511 | 234820_at | -0.0919 | 0.3362 | |
| GSE53622 | MAS1L | 116511 | 27668 | -1.9187 | 0.0000 | |
| GSE53624 | MAS1L | 116511 | 27668 | -1.2094 | 0.0000 | |
| GSE63941 | MAS1L | 116511 | 234820_at | 0.1673 | 0.2394 | |
| GSE77861 | MAS1L | 116511 | 234820_at | -0.1351 | 0.2507 | |
| GSE97050 | MAS1L | 116511 | A_23_P214565 | -0.2926 | 0.6009 | |
| SRP133303 | MAS1L | 116511 | RNAseq | -2.9074 | 0.0004 | |
| TCGA | MAS1L | 116511 | RNAseq | -4.0003 | 0.0009 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by MAS1L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MAS1L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MAS1L | 116511 | 3 | 2 | 25 | |
| GSE20123 | MAS1L | 116511 | 3 | 2 | 25 | |
| GSE43470 | MAS1L | 116511 | 5 | 0 | 38 | |
| GSE46452 | MAS1L | 116511 | 1 | 10 | 48 | |
| GSE47630 | MAS1L | 116511 | 7 | 4 | 29 | |
| GSE54993 | MAS1L | 116511 | 2 | 1 | 67 | |
| GSE54994 | MAS1L | 116511 | 11 | 4 | 38 | |
| GSE60625 | MAS1L | 116511 | 0 | 1 | 10 | |
| GSE74703 | MAS1L | 116511 | 5 | 0 | 31 | |
| GSE74704 | MAS1L | 116511 | 0 | 1 | 19 | |
| TCGA | MAS1L | 116511 | 16 | 18 | 62 |
Total number of gains: 53; Total number of losses: 43; Total Number of normals: 392.
Somatic mutations of MAS1L:
Generating mutation plots.
Highly correlated genes for MAS1L:
Showing top 20/338 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MAS1L | CMA1 | 0.750421 | 4 | 0 | 4 |
| MAS1L | MACROD2 | 0.73466 | 3 | 0 | 3 |
| MAS1L | TACC1 | 0.71869 | 3 | 0 | 3 |
| MAS1L | PDK4 | 0.71502 | 3 | 0 | 3 |
| MAS1L | PGM5 | 0.707889 | 3 | 0 | 3 |
| MAS1L | C7 | 0.690225 | 4 | 0 | 4 |
| MAS1L | PDE5A | 0.690062 | 5 | 0 | 5 |
| MAS1L | RPS9 | 0.689637 | 3 | 0 | 3 |
| MAS1L | PPP1R14A | 0.687404 | 3 | 0 | 3 |
| MAS1L | TMED5 | 0.681509 | 3 | 0 | 3 |
| MAS1L | ITGA7 | 0.680258 | 3 | 0 | 3 |
| MAS1L | MYOM1 | 0.678297 | 3 | 0 | 3 |
| MAS1L | C22orf42 | 0.676646 | 3 | 0 | 3 |
| MAS1L | UBXN10 | 0.676195 | 3 | 0 | 3 |
| MAS1L | SMTNL2 | 0.676164 | 4 | 0 | 3 |
| MAS1L | KLHL15 | 0.671973 | 3 | 0 | 3 |
| MAS1L | CALM1 | 0.668975 | 5 | 0 | 5 |
| MAS1L | OMP | 0.668453 | 3 | 0 | 3 |
| MAS1L | DCLK1 | 0.666386 | 3 | 0 | 3 |
| MAS1L | MMRN1 | 0.664476 | 4 | 0 | 4 |
For details and further investigation, click here
