Full name: calmodulin 1	Alias Symbol: CAMI|PHKD|DD132
Type: protein-coding gene	Cytoband: 14q32.11
Entrez ID: 801	HGNC ID: HGNC:1442	Ensembl Gene: ENSG00000198668	OMIM ID: 114180
Drug and gene relationship at DGIdb

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CALM1 involved pathways:

KEGG pathway	Description	View
hsa04014	Ras signaling pathway	View
hsa04015	Rap1 signaling pathway	View
hsa04020	Calcium signaling pathway	View
hsa04022	cGMP-PKG signaling pathway	View
hsa04024	cAMP signaling pathway	View
hsa04114	Oocyte meiosis	View
hsa04261	Adrenergic signaling in cardiomyocytes	View
hsa04270	Vascular smooth muscle contraction	View
hsa04713	Circadian entrainment	View
hsa04720	Long-term potentiation	View
hsa04722	Neurotrophin signaling pathway	View
hsa04728	Dopaminergic synapse	View
hsa04740	Olfactory transduction	View
hsa04750	Inflammatory mediator regulation of TRP channels	View
hsa04910	Insulin signaling pathway	View
hsa04912	GnRH signaling pathway	View
hsa04915	Estrogen signaling pathway	View
hsa04916	Melanogenesis	View
hsa04921	Oxytocin signaling pathway	View
hsa04922	Glucagon signaling pathway	View
hsa04924	Renin secretion	View
hsa04925	Aldosterone synthesis and secretion	View
hsa04970	Salivary secretion	View
hsa04971	Gastric acid secretion	View
hsa05010	Alzheimer's disease	View
hsa05031	Amphetamine addiction	View
hsa05034	Alcoholism	View
hsa05152	Tuberculosis	View
hsa05214	Glioma	View

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Expression of CALM1:

 

Dataset	Gene	EntrezID	Probe	Log2FC	Adj.pValue	Expression
GSE17351	CALM1	801	213710_s_at	-0.6968	0.3762	Show
GSE20347	CALM1	801	213710_s_at	-0.2306	0.0134	Show
GSE23400	CALM1	801	213710_s_at	-0.2752	0.0000	Show
GSE26886	CALM1	801	213710_s_at	-1.2734	0.0000	Show
GSE29001	CALM1	801	213710_s_at	-0.4849	0.0005	Show
GSE38129	CALM1	801	213710_s_at	-0.3540	0.0217	Show
GSE45670	CALM1	801	213710_s_at	-0.6824	0.0002	Show
GSE53622	CALM1	801	36210	-1.0149	0.0000	Show
GSE53624	CALM1	801	36210	-0.8436	0.0000	Show
GSE63941	CALM1	801	213710_s_at	1.4390	0.0029	Show
GSE77861	CALM1	801	213710_s_at	-0.1731	0.2163	Show
GSE97050	CALM1	801	A_24_P313186	-1.6269	0.0620	Show
SRP007169	CALM1	801	RNAseq	-1.5182	0.0000	Show
SRP008496	CALM1	801	RNAseq	-1.3872	0.0000	Show
SRP064894	CALM1	801	RNAseq	-0.5375	0.0000	Show
SRP133303	CALM1	801	RNAseq	-0.2722	0.0694	Show
SRP159526	CALM1	801	RNAseq	-0.5576	0.2778	Show
SRP193095	CALM1	801	RNAseq	-0.5566	0.0005	Show
SRP219564	CALM1	801	RNAseq	-0.9828	0.0172	Show
TCGA	CALM1	801	RNAseq	-0.1653	0.0002	Show

Upregulated datasets: 1; Downregulated datasets: 4.  Download Data

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Survival by CALM1 expression:

 

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Copy number change of CALM1:

 

Dataset	Gene	EntrezID	Gain	Loss	Normal	Detail
GSE15526	CALM1	801	9	5	16	Show
GSE20123	CALM1	801	9	5	16	Show
GSE43470	CALM1	801	7	3	33	Show
GSE46452	CALM1	801	16	3	40	Show
GSE47630	CALM1	801	11	8	21	Show
GSE54993	CALM1	801	3	8	59	Show
GSE54994	CALM1	801	19	4	30	Show
GSE60625	CALM1	801	0	2	9	Show
GSE74703	CALM1	801	6	3	27	Show
GSE74704	CALM1	801	4	4	12	Show
TCGA	CALM1	801	30	21	45	Show

Total number of gains: 114; Total number of losses: 66; Total Number of normals: 308.  Download Data

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Somatic mutations of CALM1:

 

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Highly correlated genes for CALM1:

 

Showing top 20/876 corelated genes with mean PCC>0.5.

Gene1	Gene2	Mean PCC	Num. Datasets	Num. PCC<0	Num. PCC>0.5
CALM1	CLEC3B	0.780273	3	0	3
CALM1	RASSF3	0.770136	5	0	5
CALM1	UBXN10	0.767773	4	0	3
CALM1	RBPMS2	0.755598	5	0	5
CALM1	CYP21A2	0.734935	3	0	3
CALM1	EIF4E3	0.7279	6	0	5
CALM1	XKR4	0.727344	5	0	5
CALM1	C3orf70	0.725926	5	0	4
CALM1	FGFR2	0.72549	3	0	3
CALM1	GRHL1	0.720327	3	0	3
CALM1	C1QTNF7	0.717125	5	0	5
CALM1	ZNF383	0.715819	3	0	3
CALM1	PTCHD1	0.709182	5	0	5
CALM1	PLAC9	0.708044	5	0	4
CALM1	CEP57	0.700197	3	0	3
CALM1	CADM2	0.699901	4	0	4
CALM1	SPRYD3	0.698031	3	0	3
CALM1	AMOTL1	0.695506	5	0	5
CALM1	RAB10	0.694244	3	0	3
CALM1	LDB3	0.689268	7	0	6

For details and further investigation, click here