LRRC55

 

Full name: leucine rich repeat containing 55 Alias Symbol: FLJ45686
Type: protein-coding gene Cytoband: 11q12.1
Entrez ID: 219527 HGNC ID: HGNC:32324 Ensembl Gene: ENSG00000183908 OMIM ID: 615213
Drug and gene relationship at DGIdb

 

Expression of LRRC55:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 LRRC55 219527 232856_at -0.0779 0.8268
GSE26886 LRRC55 219527 232856_at 0.0413 0.6460
GSE45670 LRRC55 219527 232856_at 0.0439 0.6154
GSE53622 LRRC55 219527 53999 0.6414 0.0001
GSE53624 LRRC55 219527 53999 0.7248 0.0000
GSE63941 LRRC55 219527 232856_at 0.0670 0.6866
GSE77861 LRRC55 219527 232856_at -0.0471 0.6342
GSE97050 LRRC55 219527 A_33_P3210735 -0.2576 0.3042
SRP133303 LRRC55 219527 RNAseq 0.3948 0.2659
TCGA LRRC55 219527 RNAseq 0.1216 0.8135

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by LRRC55 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of LRRC55:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 LRRC55 219527 1 4 25
GSE20123 LRRC55 219527 1 4 25
GSE43470 LRRC55 219527 1 5 37
GSE46452 LRRC55 219527 9 4 46
GSE47630 LRRC55 219527 3 9 28
GSE54993 LRRC55 219527 3 0 67
GSE54994 LRRC55 219527 5 6 42
GSE60625 LRRC55 219527 0 3 8
GSE74703 LRRC55 219527 1 3 32
GSE74704 LRRC55 219527 1 4 15
TCGA LRRC55 219527 14 10 72

Total number of gains: 39; Total number of losses: 52; Total Number of normals: 397.  


 

Somatic mutations of LRRC55:

 

Generating mutation plots.

 

Highly correlated genes for LRRC55:

 

Showing top 20/53 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
LRRC55YPEL20.765652303
LRRC55OCM20.762539303
LRRC55ORMDL30.747351303
LRRC55ARL2BP0.745633303
LRRC55MLYCD0.734031303
LRRC55SLC4A50.729056303
LRRC55ICAM50.725189303
LRRC55C9orf720.723926303
LRRC55SNF80.713857303
LRRC55MATN40.706226303
LRRC55GGT50.702995303
LRRC55C22orf310.686129303
LRRC55ALPK30.682614303
LRRC55EIF4ENIF10.67847303
LRRC55C12orf570.677877303
LRRC55SATB10.676518303
LRRC55KCNC40.676122403
LRRC55CRMP10.668207403
LRRC55PTGER30.661698303
LRRC55ZNF6710.654589303

For details and further investigation, click here