| Full name: NOP2/Sun RNA methyltransferase 6 | Alias Symbol: FLJ23743 | ||
| Type: protein-coding gene | Cytoband: 10p12.31 | ||
| Entrez ID: 221078 | HGNC ID: HGNC:23529 | Ensembl Gene: ENSG00000241058 | OMIM ID: 617199 |
| Drug and gene relationship at DGIdb | |||
Expression of NSUN6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NSUN6 | 221078 | 230200_at | 0.4062 | 0.3228 | |
| GSE20347 | NSUN6 | 221078 | 222128_at | 0.1337 | 0.6092 | |
| GSE23400 | NSUN6 | 221078 | 222128_at | -0.0193 | 0.6380 | |
| GSE26886 | NSUN6 | 221078 | 230200_at | 0.7239 | 0.0000 | |
| GSE29001 | NSUN6 | 221078 | 222128_at | 0.1373 | 0.6940 | |
| GSE38129 | NSUN6 | 221078 | 222128_at | -0.0144 | 0.9573 | |
| GSE45670 | NSUN6 | 221078 | 230200_at | 0.3980 | 0.0451 | |
| GSE53622 | NSUN6 | 221078 | 130015 | -0.1209 | 0.0999 | |
| GSE53624 | NSUN6 | 221078 | 130015 | 0.0706 | 0.2664 | |
| GSE63941 | NSUN6 | 221078 | 230200_at | -0.0589 | 0.9072 | |
| GSE77861 | NSUN6 | 221078 | 230200_at | 0.3301 | 0.0804 | |
| GSE97050 | NSUN6 | 221078 | A_23_P61580 | 0.2979 | 0.2743 | |
| SRP007169 | NSUN6 | 221078 | RNAseq | 0.0520 | 0.9217 | |
| SRP008496 | NSUN6 | 221078 | RNAseq | 0.1162 | 0.7407 | |
| SRP064894 | NSUN6 | 221078 | RNAseq | -0.0122 | 0.9455 | |
| SRP133303 | NSUN6 | 221078 | RNAseq | -0.0821 | 0.6754 | |
| SRP159526 | NSUN6 | 221078 | RNAseq | -0.4584 | 0.0628 | |
| SRP193095 | NSUN6 | 221078 | RNAseq | -0.1736 | 0.1364 | |
| SRP219564 | NSUN6 | 221078 | RNAseq | -0.3073 | 0.2796 | |
| TCGA | NSUN6 | 221078 | RNAseq | -0.0516 | 0.4861 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NSUN6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NSUN6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NSUN6 | 221078 | 3 | 8 | 19 | |
| GSE20123 | NSUN6 | 221078 | 3 | 7 | 20 | |
| GSE43470 | NSUN6 | 221078 | 3 | 3 | 37 | |
| GSE46452 | NSUN6 | 221078 | 1 | 14 | 44 | |
| GSE47630 | NSUN6 | 221078 | 5 | 15 | 20 | |
| GSE54993 | NSUN6 | 221078 | 10 | 0 | 60 | |
| GSE54994 | NSUN6 | 221078 | 4 | 8 | 41 | |
| GSE60625 | NSUN6 | 221078 | 0 | 0 | 11 | |
| GSE74703 | NSUN6 | 221078 | 2 | 2 | 32 | |
| GSE74704 | NSUN6 | 221078 | 0 | 6 | 14 | |
| TCGA | NSUN6 | 221078 | 18 | 25 | 53 |
Total number of gains: 49; Total number of losses: 88; Total Number of normals: 351.
Somatic mutations of NSUN6:
Generating mutation plots.
Highly correlated genes for NSUN6:
Showing top 20/223 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NSUN6 | CNTRL | 0.77621 | 3 | 0 | 3 |
| NSUN6 | TMEM182 | 0.729383 | 3 | 0 | 3 |
| NSUN6 | TNFRSF10A | 0.723987 | 3 | 0 | 3 |
| NSUN6 | NIFK | 0.718233 | 3 | 0 | 3 |
| NSUN6 | FPR1 | 0.715401 | 3 | 0 | 3 |
| NSUN6 | ZNF697 | 0.713849 | 3 | 0 | 3 |
| NSUN6 | PLEC | 0.711516 | 3 | 0 | 3 |
| NSUN6 | CDK12 | 0.700111 | 3 | 0 | 3 |
| NSUN6 | WDR53 | 0.697156 | 4 | 0 | 4 |
| NSUN6 | RRP12 | 0.69041 | 5 | 0 | 4 |
| NSUN6 | TMEM223 | 0.682496 | 3 | 0 | 3 |
| NSUN6 | NSUN2 | 0.68243 | 3 | 0 | 3 |
| NSUN6 | ADAMTS2 | 0.6789 | 3 | 0 | 3 |
| NSUN6 | SPC25 | 0.676336 | 3 | 0 | 3 |
| NSUN6 | ZNF77 | 0.675041 | 3 | 0 | 3 |
| NSUN6 | TGIF1 | 0.674121 | 3 | 0 | 3 |
| NSUN6 | EXT1 | 0.672619 | 3 | 0 | 3 |
| NSUN6 | TMEM163 | 0.672326 | 3 | 0 | 3 |
| NSUN6 | PUS7 | 0.670983 | 3 | 0 | 3 |
| NSUN6 | SH3BP4 | 0.668778 | 3 | 0 | 3 |
For details and further investigation, click here
