| Full name: family with sequence similarity 53 member B | Alias Symbol: bA12J10.2|smp | ||
| Type: protein-coding gene | Cytoband: 10q26.13 | ||
| Entrez ID: 9679 | HGNC ID: HGNC:28968 | Ensembl Gene: ENSG00000189319 | OMIM ID: 617289 |
| Drug and gene relationship at DGIdb | |||
Expression of FAM53B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FAM53B | 9679 | 203206_at | 0.5179 | 0.2928 | |
| GSE20347 | FAM53B | 9679 | 203206_at | -0.2490 | 0.0626 | |
| GSE23400 | FAM53B | 9679 | 203206_at | -0.2352 | 0.0000 | |
| GSE26886 | FAM53B | 9679 | 203206_at | -0.2563 | 0.1989 | |
| GSE29001 | FAM53B | 9679 | 203206_at | -0.0310 | 0.8817 | |
| GSE38129 | FAM53B | 9679 | 203206_at | -0.2499 | 0.0431 | |
| GSE45670 | FAM53B | 9679 | 203206_at | 0.0036 | 0.9821 | |
| GSE53622 | FAM53B | 9679 | 96563 | -0.3311 | 0.0071 | |
| GSE53624 | FAM53B | 9679 | 96563 | -0.0969 | 0.2467 | |
| GSE63941 | FAM53B | 9679 | 203206_at | 0.6658 | 0.1214 | |
| GSE77861 | FAM53B | 9679 | 203206_at | -0.1675 | 0.3457 | |
| GSE97050 | FAM53B | 9679 | A_23_P104509 | -0.2000 | 0.3560 | |
| SRP007169 | FAM53B | 9679 | RNAseq | -0.8204 | 0.0916 | |
| SRP008496 | FAM53B | 9679 | RNAseq | -0.4918 | 0.1174 | |
| SRP064894 | FAM53B | 9679 | RNAseq | -0.1961 | 0.2807 | |
| SRP133303 | FAM53B | 9679 | RNAseq | -0.5120 | 0.0001 | |
| SRP159526 | FAM53B | 9679 | RNAseq | -0.5675 | 0.1056 | |
| SRP193095 | FAM53B | 9679 | RNAseq | 0.0820 | 0.3566 | |
| SRP219564 | FAM53B | 9679 | RNAseq | 0.1483 | 0.6672 | |
| TCGA | FAM53B | 9679 | RNAseq | -0.0428 | 0.4551 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FAM53B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FAM53B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FAM53B | 9679 | 1 | 8 | 21 | |
| GSE20123 | FAM53B | 9679 | 1 | 8 | 21 | |
| GSE43470 | FAM53B | 9679 | 0 | 10 | 33 | |
| GSE46452 | FAM53B | 9679 | 0 | 11 | 48 | |
| GSE47630 | FAM53B | 9679 | 2 | 14 | 24 | |
| GSE54993 | FAM53B | 9679 | 8 | 1 | 61 | |
| GSE54994 | FAM53B | 9679 | 2 | 8 | 43 | |
| GSE60625 | FAM53B | 9679 | 0 | 0 | 11 | |
| GSE74703 | FAM53B | 9679 | 0 | 6 | 30 | |
| GSE74704 | FAM53B | 9679 | 1 | 3 | 16 | |
| TCGA | FAM53B | 9679 | 4 | 28 | 64 |
Total number of gains: 19; Total number of losses: 97; Total Number of normals: 372.
Somatic mutations of FAM53B:
Generating mutation plots.
Highly correlated genes for FAM53B:
Showing top 20/375 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FAM53B | CSNK1D | 0.868026 | 3 | 0 | 3 |
| FAM53B | MCMBP | 0.831234 | 3 | 0 | 3 |
| FAM53B | PRR3 | 0.805214 | 3 | 0 | 3 |
| FAM53B | FOXP4 | 0.786497 | 3 | 0 | 3 |
| FAM53B | HIC2 | 0.786411 | 3 | 0 | 3 |
| FAM53B | TBCC | 0.785537 | 3 | 0 | 3 |
| FAM53B | RRP1B | 0.78096 | 3 | 0 | 3 |
| FAM53B | MTCH2 | 0.761494 | 3 | 0 | 3 |
| FAM53B | DTX4 | 0.759109 | 3 | 0 | 3 |
| FAM53B | STRADA | 0.753392 | 3 | 0 | 3 |
| FAM53B | KCTD15 | 0.749987 | 4 | 0 | 4 |
| FAM53B | CUL7 | 0.749861 | 3 | 0 | 3 |
| FAM53B | LARP1B | 0.743825 | 3 | 0 | 3 |
| FAM53B | KRI1 | 0.739836 | 3 | 0 | 3 |
| FAM53B | C2CD2 | 0.738829 | 4 | 0 | 3 |
| FAM53B | VPS26B | 0.736758 | 4 | 0 | 3 |
| FAM53B | PCNT | 0.736721 | 4 | 0 | 3 |
| FAM53B | KLHDC3 | 0.730878 | 5 | 0 | 5 |
| FAM53B | XRRA1 | 0.728481 | 3 | 0 | 3 |
| FAM53B | MPHOSPH9 | 0.727723 | 3 | 0 | 3 |
For details and further investigation, click here
